Clinical trials
Phenotype clinical trials
Below are recruiting phenotype clinical trials, each written for real people, not researchers. We’re tracking 318 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06269900RecruitingPhase 3
Dexamethasone for Severe Hospital-Acquired Pneumonia with Inflammation
This trial tests whether adding the anti-inflammatory drug dexamethasone to standard antibiotics improves recovery from severe hospital-acquired pneumonia in critically ill patients on a ventilator.
AmiensAges 18–85 - NCT06278428Recruiting
Epilepsy in Infants: Genes and Disease Course
This study looks at children with severe epilepsy that starts before age 2. It aims to understand how different gene changes affect the disease and how it progresses over time.
Ho Chi Minh CityAges Up to 1.9 years - NCT06292104Recruiting
Understanding POTS: A study on heart rate and standing
This study looks at how the body controls heart rate and blood flow in people with POTS (a condition that causes dizziness and a fast heart rate upon standing). It helps researchers understand POTS better by comparing patients with healthy volunteers.
Dallas, TexasAges 14 years+ - NCT06298721Recruiting
Personalized care to improve knee replacement satisfaction
This study tests a personalized approach to knee replacement surgery designed for people who are at higher risk of being dissatisfied after the procedure. The goal is to see if tailoring care based on patient-reported outcomes can improve satisfaction.
Cleveland, OhioAges 18–80 - NCT06315348Recruiting
Gum shaping during braces with a vibration tool
This trial tests a new, less invasive surgical technique (using a special tool that vibrates, not a scalpel) to help reshape the gums while straightening teeth with braces. It is for people who need braces for mild to moderate crowding and have healthy gums.
MadridAges 16–70 - NCT06318585Recruiting
Building a database for motor neuron disease research
This study collects information from people with ALS or other motor neuron diseases to better understand how these conditions vary. By joining a database, you help researchers find patterns that could improve care.
Milan, MIAges 18 years+ - NCT06318598Recruiting
ALS and motor neuron disease biomarker study
This study looks for biological markers in people with ALS or other motor neuron diseases to better understand the different types of the disease. It may help find new ways to treat or manage these conditions.
Milan, MIAges 18 years+ - NCT06321965Recruiting
Study of SMA in Children on SMN-Boosting Therapies
This study is looking for children and teens with spinal muscular atrophy (SMA) who are already on a treatment like Spinraza, Evrysdi, or Zolgensma. The goal is to understand different forms of SMA and how the treatment affects them over time.
Bron, RhoneAges birth–16 years - NCT06376448Recruiting
Chronic cough study using a new questionnaire
This study aims to better understand different types of chronic cough by using a new questionnaire. If you have had a cough for at least 8 weeks and do not smoke, you may be able to help.
Cottingham, East YorkshiureAges 18 years+ - NCT06383338RecruitingPhase 1
Metabolism Changes in Young People with Lymphoma
This study looks at how your body's metabolism (processing of food and medicine) changes after you start treatment for lymphoma. It uses two safe, commonly used drugs (omeprazole and dextromethorphan) to measure these changes.
Melbourne, VictoriaAges 6–25 - NCT06396312Recruiting
Predicting lithium response in difficult depression
This study looks at how to predict which people with hard-to-treat depression will benefit from adding lithium to their antidepressant. If you have treatment-resistant depression and are considering lithium, this trial may help find the best treatment for you.
Munich, BavariaAges 18 years+ - NCT06396871Recruiting
Blood cell study in metabolic diseases
This study looks at blood cells and factors in people with metabolic diseases like fatty liver, prediabetes, or type 2 diabetes. It aims to better understand these conditions by comparing them with healthy volunteers.
Dresden, SaxonyAges 18 years+ - NCT06397677Recruiting
Study of Progressive RA Interstitial Lung Disease
This study is looking at people with rheumatoid arthritis (RA) who also have interstitial lung disease (ILD), a condition that causes scarring in the lungs. It aims to understand how the disease changes over time by using imaging and blood tests, without providing any new treatments right now.
San Francisco, CaliforniaAges 18–90 - NCT06400550Recruiting
Melanoma metabolism and spread risk study
This study looks at how the body's metabolism might affect the spread of melanoma. Researchers want to see if certain metabolic traits in people with melanoma are linked to a higher risk of the cancer spreading.
Dallas, TexasAges 18 years+ - NCT06405997Recruiting
Study of LAM: genes and symptoms
This study looks at the genes and physical traits of people with lymphangioleiomyomatosis (LAM), a rare lung disease that causes cysts. It aims to help better understand and treat LAM.
TaipeiAges 18 years+ - NCT06419413Recruiting
Asthma study in Chinese adults to find better treatment matches
This study looks at how asthma affects people in China and tries to find patterns that might help predict which treatments work best. If you have asthma and are between 18 and 75, you may be able to join.
Chengdu, SichuanAges 18–75 - NCT06427421Recruiting
Immune cells in children with recent type 1 diabetes
This study looks at immune cells in children who were recently diagnosed with type 1 diabetes. It involves one extra blood draw to better understand how the immune system attacks the pancreas. If you join, no new treatments are given—just observation and analysis of your child's immune cells.
ParisAges 6–18 - NCT06444646Recruiting
Studying fat cell particles in obesity
This study looks at tiny particles released from fat tissue in people with and without obesity. It aims to understand differences that might help explain obesity-related health problems.
Genk, LimburgAges 18–65 - NCT06465043Recruiting
Understanding Heart Failure When the Heart Stiffens
This study is for people with a type of heart failure called HFpEF, where the heart pumps normally but doesn't relax well. It aims to better understand heart failure through advanced testing, and it includes people who are newly diagnosed or have had a recent hospitalization.
HelsinkiAges 18–85 - NCT06466941Recruiting
Understanding acute pain after surgery
This study surveys surgical patients about their pain and emotional experience to better understand acute pain. You may help by answering questions or sharing your story.
Boston, MassachusettsAges 18 years+ - NCT06475976Recruiting
Identifying lung types in severe BPD in preemies
This study looks at babies born very early who have severe lung disease (grade 3 BPD) and still need a breathing machine. Researchers will use tests to understand their lung problems better, which may help guide their care.
Philadelphia, PennsylvaniaAges 1 month–1 year - NCT07203768Recruiting
Study on how essential thrombocythemia evolves into polycythemia vera
This study watches how a blood condition called essential thrombocythemia (ET) changes into another condition called polycythemia vera (PV) in people with a specific JAK2 mutation. It aims to learn more about these changes and what happens to patients over time.
Rochester, MinnesotaAges 18–100 - NCT06491615Recruiting
eyeGENE study: genetics of rare eye diseases
This study collects DNA samples and medical information from people with rare inherited eye diseases and their close relatives. The goal is to learn more about the genetic causes of these conditions and improve diagnosis and care.
Bethesda, MarylandAges 1 day–120 years - NCT06498089RecruitingPhase 4
Comparing tailored vs. standard treatment for active Takayasu's arteritis.
This trial compares a personalized treatment plan based on your specific disease markers to standard care, aiming to find which is more effective and safer for active Takayasu's arteritis. It may help researchers learn how to better control inflammation and prevent flares.
Shanghai, Shanghai MunicipalityAges 18–65
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Common questions
- Are there clinical trials for phenotype?
- Yes. Clin2 currently lists 318 recruiting phenotype studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a phenotype trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a phenotype trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.