Clin2
NCT06051240Possibly a fitRecruiting

Lithium to prevent thinking problems after brain radiation

Cognitive ImpairmentCognitive DeclineRadiotherapy Side EffectRadiotherapy; ComplicationsBrain TumorMemory ImpairmentLate Effect of Radiation

Treatments studied

Part of Brain & nervous system, Cancer, Injuries & trauma, Mental health clinical trials.

This study tests if the drug lithium can help prevent memory and thinking problems that sometimes happen after brain radiation for a brain tumor. You may qualify if you are under 18 when treated and had radiation within the last 7 years.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
84 people
Ages
5 years and older
Study type
Interventional

Who can take part

  • You are older than 5 and younger than 18 when you had radiation.
  • The radiation was to your brain or spine and happened within the last 7 years.
  • You don't have serious kidney, heart, or thyroid problems.
  • You are not pregnant or breastfeeding.
  • You can swallow pills and are willing to follow the study plan.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06594172Not yet recruiting· Phase 2
Medications to protect memory during brain radiation

This study tests whether two medications, memantine and pioglitazone, can help protect your memory and thinking skills during and after radiation therapy for brain tumors. It may help you keep your mental sharpness while treating the cancer.

NCT05727605Recruiting
Thinking changes after radiotherapy for brain and skull-base tumors

This trial studies how radiotherapy affects memory and thinking in adults with certain brain or skull-base tumors. It may help doctors understand who is most likely to have thinking changes and how to monitor or support patients.

Ghent
NCT07470606Recruiting· Phase 2
Memantine and raloxifene for brain protection during radiation

This trial tests whether two medications, memantine and raloxifene, can help protect memory and thinking abilities during radiation therapy for brain tumors. It is for people who are about to start or have started radiation therapy for a solid tumor in the brain.

San Antonio, Texas
NCT04306432Recruiting
Check how cognitive tests change after brain tumor radiation

This trial studies how radiation therapy affects thinking and memory in adults with certain brain tumors. It may help doctors understand which patients are more likely to have cognitive side effects and how to measure them over time.

Copenhagen, Capital Region
NCT05658731Recruiting
Radiation planning study to protect thinking in children

This study compares how radiation is planned to see whether it better protects thinking and memory in children and young adults. It may help future patients by learning which planning approach leads to better cognitive (thinking) outcomes.

Washington D.C., District of Columbia
NCT06275035Recruiting· Phase 3
Memantine for memory protection during brain radiation

This trial tests whether a medicine called memantine can help protect memory and thinking skills in people getting radiation to the brain and spine. If you qualify, you would receive memantine or a placebo during your treatment.

Mumbai, Maharashtra

Hear when a new Cognitive Impairment trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.