Clinical trials
PTSD clinical trials
Below are recruiting ptsd clinical trials, each written for real people, not researchers. We’re tracking 292 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05889741RecruitingPhase 2
Stellate nerve block plus prolonged therapy for PTSD symptoms
This Phase 2 study tests whether a procedure called a stellate ganglion block, combined with prolonged exposure therapy, can reduce PTSD symptoms in military members. It may help by targeting the body’s stress signaling while you work on trauma-related memories with guided therapy.
Fort Hood, TexasAges 18–65 - NCT05895006Recruiting
Study brain responses in PTSD using stimulation and brain scans
This study looks at how anxiety and stress show up in the brain in people with PTSD, using brain stimulation and brain scanning. If you’re eligible, it may help researchers understand your symptoms and how they relate to brain activity.
Houston, TexasAges 18–50 - NCT05934162Recruiting
Internet cognitive therapy for PTSD symptoms
This study tests whether therapist-guided cognitive-behavior therapy delivered over the internet can reduce PTSD symptoms. If you have PTSD and can use Swedish online materials, you may be able to take part without traveling to clinic visits.
StockholmAges 18 years+ - NCT05959434RecruitingPhase 2
Therapy program to reduce drinking relapse and PTSD symptoms
This Phase 2 study tests a combined therapy approach for people who have both alcohol use disorder and post-traumatic stress disorder (PTSD). It aims to help you process stressful memories and lower the chances of relapse back to heavy drinking.
Charleston, South CarolinaAges 18 years+ - NCT05989841RecruitingPhase 1/Phase 2
Helping women after sexual assault who use cannabis
This study tests a new approach to help women who have recently experienced a sexual assault and use cannabis. It explores whether reducing anxiety about physical symptoms can help prevent long-term PTSD and cannabis problems.
Minneapolis, MinnesotaAges 18 years+ - NCT05995678Recruiting
STEP Home Workshop for veterans adjusting to civilian life
This pilot study tests a workshop called STEP Home to help veterans who recently left the military and are having trouble readjusting. The goal is to improve their transition and reduce suicide risk.
Boston, MassachusettsAges 18–65 - NCT06002633Recruiting
Alcohol effects and brain responses in PTSD
This study explores how people with PTSD respond to alcohol and how their brains handle approach or avoidance situations. You may participate if you drink alcohol occasionally and are between 21 and 60 years old.
Austin, TexasAges 21–60 - NCT06035809Recruiting
Smart treatment study for PTSD using brain activity feedback
This study tests a new therapy called SMART, which uses brain imaging to help regulate arousal linked to PTSD. It aims to see if combining brain feedback with therapy reduces PTSD symptoms.
London, OntarioAges 18–65 - NCT06037785Recruiting
Self-management support after an ICD shock
This study tests a self-management program to help people who have received a shock from their implantable cardioverter-defibrillator (ICD). The goal is to see if this program can improve recovery and well-being after a shock.
Seattle, WashingtonAges 18 years+ - NCT06088303Recruiting
Improving PTSD treatment through better communication
This study tests if improving how you talk with your doctor can make PTSD treatment work better. You can join if you have PTSD and have been on stable medications for at least 4 weeks.
Boston, MassachusettsAges 18 years+ - NCT06117306RecruitingPhase 3
MDMA therapy and PTSD in veterans
This study tests if combining MDMA with therapy can help veterans with PTSD. The treatment involves taking MDMA during therapy sessions while focusing on past trauma.
San Diego, CaliforniaAges 18–64 - NCT06127342Recruiting
Exercise and emotional learning for PTSD
This study tests whether exercise can help people with PTSD learn to feel safer in their bodies. You will do some exercise sessions and emotional learning tasks, and have an MRI brain scan to see how your brain changes.
Lexington, KentuckyAges 18–64 - NCT06162741Recruiting
Brief mindfulness training for Veterans in primary care
This study tests whether brief mindfulness training offered in VA primary care can help Veterans with symptoms of PTSD, depression, or anxiety. It aims to see if this approach works well in everyday clinic settings.
Phoenix, ArizonaAges 18 years+ - NCT06185244Recruiting
Online trauma therapy for teens with PTSD
This study tests an online therapy for teenagers with PTSD. It's a type of talk therapy that helps you deal with trauma, and you and your parent take part from home.
StockholmAges 13–17 - NCT06203106Recruiting
NYSCF Scientific Discovery Biobank
This study collects blood, saliva, or skin samples from people with certain neurological conditions and from healthy volunteers to help researchers better understand and find treatments for these diseases.
New York, New YorkAges 4 weeks+ - NCT06210711Recruiting
Prolonged exposure therapy for trauma injury patients
This study tests if prolonged exposure therapy can help people who were injured in a trauma and admitted to a Level I trauma center. It aims to reduce the psychological impact of the traumatic event, such as PTSD symptoms.
Dallas, TexasAges 18–75 - NCT06219408Recruiting
Stepped care for chronic pain and PTSD
This study tests a stepped-care program that combines complementary health approaches for people who have both chronic pain and PTSD. It aims to help patients manage both conditions together using treatments like acupuncture, massage, or mind-body therapy.
Seattle, WashingtonAges 18 years+ - NCT06261463Recruiting
Peer-led support group for refugee families in Chicago
This study is testing a support program led by trained peers to help refugee families strengthen family bonds and cope with challenges. It is designed for Arabic-speaking families who have recently settled in Chicago.
Chicago, IllinoisAges 12–55 - NCT06278922Recruiting
A therapy toolkit for Deaf people with alcohol and trauma issues
This study tests a therapy toolkit designed for Deaf or hard-of-hearing people who struggle with alcohol use and have experienced trauma. The therapy is provided in ASL via video sessions, and the goal is to see if it helps reduce drinking and PTSD symptoms.
Worcester, MassachusettsAges 18 years+ - NCT06279598Recruiting
Predicting PTSD treatment success and handling non-response (PT-STRESS)
This study looks at how well PTSD treatments work and what happens when they don't. It tests ways to predict if a treatment will be successful for you.
DeventerAges 18–65 - NCT06288711Recruiting
Video therapy for PTSD in people taking opioid medication
This trial tests a therapy called prolonged exposure (a type of talk therapy) delivered via video calls to help people with both opioid use disorder and PTSD. It aims to see if this approach can reduce PTSD symptoms.
Burlington, VermontAges 18 years+ - NCT06289621Recruiting
Brief treatment for anxiety and PTSD in South Africa
This trial tests a short, talk-based therapy for people with anxiety disorders or PTSD. It aims to help you manage symptoms in fewer sessions.
Cape TownAges 18–65 - NCT06296186Recruiting
PTSD treatment for veterans in substance use recovery
This trial tests a condensed form of prolonged exposure therapy for PTSD in veterans who are also receiving treatment for a substance use disorder. The goal is to help you process trauma and reduce substance use together.
San Diego, CaliforniaAges 18 years+ - NCT06300255Recruiting
Evaluation of the H.O.O.V.E.S. Healing Program
This study looks at a program called H.O.O.V.E.S. Healing Intensives for veterans. It aims to understand how the program helps participants.
Salt Lake City, UtahAges 18–120
Hear when a new PTSD trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for ptsd?
- Yes. Clin2 currently lists 292 recruiting ptsd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ptsd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ptsd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.