Clinical trials
Pouchitis clinical trials
Below are recruiting pouchitis clinical trials, each written for real people, not researchers. We’re tracking 6 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05829109RecruitingEarly Phase 1
Stool transplant for long-term inflamed pouch after surgery
This early-phase study tests fecal microbiota transplant (a stool-based treatment) to improve chronic pouchitis symptoms in adults after UC-related surgery. It may help by changing gut bacteria, especially for people who need ongoing antibiotics or keep having flare-ups.
New York, New YorkAges 18 years+ - NCT06443502RecruitingPhase 3
Vedolizumab for children with chronic pouchitis
This study tests a medicine called vedolizumab to see if it is safe and helps children and teenagers with chronic pouchitis (inflammation in the pouch after colon removal). It is for kids who have not had good results with other treatments.
Leuven, Vlaams-BrabantAges 2–17 - NCT06312683RecruitingPhase 4
Rifaximin to prevent pouchitis from coming back
This trial tests whether the antibiotic rifaximin can prevent pouchitis from coming back after a first episode. It is for people who had ulcerative colitis, have a J-pouch, and developed pouchitis within the first year after their final surgery.
New York, New YorkAges 18–74 - NCT06916390RecruitingPhase 4
Testing guselkumab with antibiotics for chronic pouchitis
This study tests whether adding a medication called guselkumab to antibiotics can help people with chronic or recurring pouchitis, a condition that causes inflammation in the J-pouch after ulcerative colitis surgery. Participants will take antibiotics for the first 4 weeks and guselkumab as an injection over the course of the trial.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07486921RecruitingPhase 2
Etrasimod to prevent pouchitis after ulcerative colitis surgery
This trial tests if etrasimod can prevent pouchitis, which is inflammation of the surgically created internal pouch, in people who have had their colon removed due to ulcerative colitis. If you are at high risk for pouchitis or have had only one episode, this study may help keep your pouch healthy.
New York, New YorkAges 18–65 - NCT06864403RecruitingPhase 4
Mirikizumab for chronic pouch inflammation
This trial tests if mirikizumab can help people with chronic inflammation of the pouch (a surgically created internal reservoir) that doesn't respond well to antibiotics or acts like Crohn's disease. It aims to see if the drug can reduce symptoms like urgency, pain, and bleeding.
Los Angeles, CaliforniaAges 18–80
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Pouchitis trials by city
Studies with a site in or near these metro areas.
Pouchitis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for pouchitis?
- Yes. Clin2 currently lists 6 recruiting pouchitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pouchitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pouchitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.