Clinical trials · North Carolina
Pregnancy clinical trials in North Carolina
We’re tracking 51 recruiting pregnancy studies with a site in North Carolina — including Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT06942598Recruiting
Food support program for pregnant women facing food insecurity
This trial tests a program to help pregnant women who have trouble getting enough food. It provides special meals and support to improve food security and health for both mother and baby.
Winston-Salem, North CarolinaAges 18 years+ - NCT06866405RecruitingPhase 3
RSV vaccine boost in a new pregnancy
This study tests whether a second dose of the RSV vaccine during a new pregnancy protects you and your baby from RSV. If you received the RSVpreF or Abrysvo vaccine in a past pregnancy, you may be able to join.
Durham, North CarolinaAges birth+ - NCT06744231Enrolling by invitation
Thriving Hearts Postpartum Parent Survey
This study is for new parents in certain North Carolina counties who had a baby in the past 6 months. You will fill out a one-time survey to help improve maternity care and support for families.
Chapel Hill, North CarolinaAges 15 years+ - NCT06628687Recruiting
Study checking omaveloxolone health effects during pregnancy and breastfeeding
This study follows people with Friedreich's ataxia who took omaveloxolone during pregnancy or while breastfeeding, to check how the drug affected their health and their baby's health. It helps doctors understand the safety of this treatment for mothers and babies.
Morrisville, North CarolinaAges 16 years+ - NCT06598098Recruiting
Healthy Weight and Exercise in Early Pregnancy Study
This study looks at how exercise during early pregnancy (first 16 weeks) may help women with a healthy body weight. Researchers want to see if staying active can support a healthy pregnancy and baby.
Greenville, North CarolinaAges 18–40 - NCT06533098RecruitingPhase 3
Nipocalimab vs IVIG for FNAIT in pregnancy
This study tests a new medicine called nipocalimab compared to standard IVIG treatment for pregnant women who are at risk of a serious condition where the mother's antibodies attack the baby's platelets (FNAIT). The goal is to see if nipocalimab can prevent complications like bleeding in the baby.
Chapel Hill, North CarolinaAges 18–45 - NCT06498128Recruiting
Pregnancy safety registry for insomnia drug QUVIVIQ
This registry follows pregnant women with insomnia who used or did not use the sleep medication QUVIVIQ. It aims to track pregnancy and baby outcomes to understand safety.
Durham, North CarolinaAges 15–50 - NCT06445946RecruitingPhase 4
Metformin vs insulin for gestational diabetes
This study compares two common medicines (metformin pills and insulin shots) to see which works better for controlling blood sugar in pregnant women with gestational diabetes. The goal is to find the best treatment for both mom and baby, now and in the long term.
Chapel Hill, North CarolinaAges 18 years+ - NCT06433765Recruiting
BRIUMVI and pregnancy safety in multiple sclerosis
This study looks at the effects of the MS medication BRIUMVI on pregnancy and baby health. It compares women who took BRIUMVI during pregnancy to those who did not.
Wilmington, North CarolinaAges 15–50 - NCT06411158Recruiting
Pelvic floor training for urine leakage after first baby
This study tests whether a pelvic floor training program delivered through a smartphone app can help first-time moms who leak urine after childbirth. The program is designed for women who had a vaginal delivery with certain risk factors for ongoing pelvic floor issues.
Durham, North CarolinaAges 18 years+ - NCT06413420Recruiting
Pregnancy registry for narcolepsy or sleep apnea treatments
This study tracks the health of pregnant women who have narcolepsy or sleep apnea, or who have taken certain wake-promoting medications during pregnancy. It helps researchers learn more about the safety of these treatments for mothers and babies.
Morrisville, North CarolinaAges Any age - NCT06150781Recruiting
Aimovig pregnancy safety study for migraine
This study tracks the health of pregnant women with migraine who take Aimovig. It helps doctors understand if the medicine is safe to use during pregnancy.
Durham, North CarolinaAges 18–99 - NCT06036446Recruiting
Late cerclage for preventing early birth in high-risk pregnancies
This trial tests if placing a stitch in the cervix (cerclage) between 24 and 27 weeks of pregnancy can help prevent preterm birth in women whose cervix is short. It may be an option for those who find out late in pregnancy that they are at risk.
Charlotte, North CarolinaAges 18–50 - NCT06002165Enrolling by invitation
Testing Ways to Improve Care for High Blood Pressure in Pregnancy
This study tests ways to help clinics follow a set of best practices for managing severe high blood pressure during and after pregnancy. It wants to see if the new approach helps clinics treat high blood pressure faster and more effectively.
Chapel Hill, North CarolinaAges birth–99 years - NCT05912517RecruitingPhase 3
Nipocalimab for high-risk pregnancy blood disease
This Phase 3 trial tests nipocalimab (an antibody medicine) to help prevent severe blood breakdown in a baby when a parent has certain blood antibodies. It enrolls people who previously had severe hemolytic disease in a past pregnancy and who are currently early in pregnancy with the same risk antibodies.
Chapel Hill, North CarolinaAges 18–45 - NCT05756244Recruiting
Managing blood thinners during pregnancy to prevent clot problems
This study looks at the best way to manage blood thinners (like injections of LMWH) during pregnancy for people who need them because of a past or current blood clot risk. It may help by improving how safely and effectively anticoagulation is handled to reduce clot complications.
Durham, North CarolinaAges 18–60 - NCT05658497Recruiting
MS pregnancy registry for Vumerity (diroximel fumarate) exposure
This study collects information about pregnancies in people with multiple sclerosis (MS) who were exposed to Vumerity (diroximel fumarate) or who were not on MS medicines during pregnancy. It helps researchers understand pregnancy outcomes and safety in these situations.
Durham, North CarolinaAges Any age - NCT05579548Recruiting
Study of Pegvaliase use in pregnancy and breastfeeding for PKU
This study looks at how taking Pegvaliase during pregnancy and breastfeeding affects pregnancy, baby health, and early infant outcomes in people with PKU. It may help improve care guidance for patients and babies exposed to Pegvaliase before birth.
Wilmington, North CarolinaAges Any age - NCT05158894Recruiting
Pregnancy safety registry for migraine medicines Ubrelvy and Qulipta
This is an observational study (no treatment is assigned) that tracks side effects and pregnancy outcomes in people taking Ubrelvy or Qulipta for migraine during pregnancy. It may help doctors better understand how these medicines affect mothers and babies.
Durham, North CarolinaAges 18 years+ - NCT05484804Recruiting
Improving Black maternal care by undoing inequities
This study tests a care improvement plan in prenatal clinics to reduce inequities in how care is delivered to Black pregnant people. It may help clinics change practices and use tools that better spot problems early and improve support like doula care.
Chapel Hill, North CarolinaAges 12–99 - NCT03276923Recruiting
Pregnancy registry for women with autoimmune disease
This study is a pregnancy and health registry for women with autoimmune (immune system) conditions who are trying to become pregnant or are already pregnant. It helps researchers better understand pregnancy outcomes and health needs in autoimmune disease.
Durham, North CarolinaAges Any age - NCT04364503Enrolling by invitation
Study that analyzes de-identified patient samples and records
This trial checks how well patient samples and health records can be analyzed when names are removed (“de-identified”) and privacy rules are followed. You might be included if you agree in writing and your sample data can be used for this research and/or your doctor requests it.
Burlington, North CarolinaAges Any age - NCT01073475Recruiting
Pregnancy and birth registry for community health research
This trial is a long-term registry that collects pregnancy and birth information in a community to help researchers study maternal and newborn health. It may help you and others by improving understanding of care and outcomes across many pregnancies.
Chapel Hill, North CarolinaAges Any age - NCT00196742Recruiting
Fabry disease registry and pregnancy follow-up
This study collects health information from people with Fabry disease and specifically from pregnant people with Fabry disease. It helps researchers better understand the condition and how pregnancy affects health, using information you already experience in routine care.
Charlotte, North CarolinaAges Any age
Pregnancy trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting pregnancy studies listed above.
- University of North Carolina at Chapel Hill · 4 studies
- Duke University Medical Center · 3 studies
- Atrium Health Carolinas Medical Center · 2 studies
- IQVIA US Office · 2 studies
- University of North Carolina · 2 studies
- Wake Forest University Health Sciences · 2 studies
- BRIUMVI® Pregnancy Registry Virtual Research Coordination Center
- Duke University Hospital
What taking part in a pregnancy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pregnancy trials in other states
Common questions
- Are there pregnancy clinical trials in North Carolina?
- Yes. We're currently tracking 51 recruiting pregnancy studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pregnancy study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pregnancy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pregnancy studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.