Clinical trials · Massachusetts
Pregnancy clinical trials in Massachusetts
We’re tracking 31 recruiting pregnancy studies with a site in Massachusetts — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT05388643Recruiting
Early screening for gestational diabetes during early pregnancy
This study tests whether checking for gestational diabetes (diabetes that starts in pregnancy) early can help identify it sooner in people at higher risk. You may be asked to do a glucose test during your first prenatal visits so clinicians can monitor and respond earlier.
Worcester, MassachusettsAges 18 years+ - NCT06575868Recruiting
Can myo-inositol prevent gestational diabetes in pregnancy?
This study tests whether a supplement called myo-inositol (a natural sugar-like substance) can help prevent gestational diabetes in pregnant women with obesity. If you join, you will wear a continuous glucose monitor to track your blood sugar levels and might take the supplement or a placebo.
Boston, MassachusettsAges 18–45 - NCT07009704Recruiting
Glucose monitoring and support in pregnancy study
This study tests whether using a continuous glucose monitor (a small sensor that tracks your blood sugar) along with support from others can help prevent or manage high blood sugar during pregnancy. It is for pregnant women under 20 weeks who have certain risk factors for gestational diabetes.
Boston, MassachusettsAges 18–45 - NCT06986824RecruitingPhase 4
Pelvic wand massage in late pregnancy
This trial tests whether gently massaging the perineum with a special pelvic wand during late pregnancy can help prepare for birth. It is offered to people who plan to deliver at Beth Israel Deaconess Medical Center.
Boston, MassachusettsAges 18 years+ - NCT06835959Recruiting
Moms at Home: A story-based app to manage blood pressure in pregnancy
This study tests if using a storytelling app on your smartphone can help you better manage your blood pressure during pregnancy. You would share your blood pressure readings at home and use the app as part of your care.
Worcester, MassachusettsAges 18–50 - NCT06822439Recruiting
Remote fetal monitoring for high-risk pregnancies
This study tests if remote monitoring of your baby's heartbeat from home is a safe and effective option for high-risk pregnancies. It may reduce the need for frequent hospital visits.
Boston, MassachusettsAges 18 years+ - NCT06312644Recruiting
Study of Ultomiris safety during pregnancy
This study looks at the safety of the medication Ultomiris when taken during pregnancy or breastfeeding. If you are pregnant and currently taking Ultomiris for an approved condition, this research will help gather information on how it affects you and your baby.
Boston, MassachusettsAges Any age - NCT05317585Recruiting
Continuous glucose monitor use during early pregnancy with type 2 diabetes
This study tests whether using a continuous glucose monitor during pregnancy is useful for people with type 2 diabetes. It may help track blood sugar levels more closely to support safer pregnancy care.
Worcester, MassachusettsAges 18 years+ - NCT05264779Recruiting
Decision help tool for very early delivery planning
This study tests a decision-support tool (a structured way to guide conversations) for parents facing a high risk of delivering very early (about 22–26 weeks). It may help you and your baby’s care team make clearer, more aligned choices about neonatal (newborn) treatment.
Worcester, MassachusettsAges 18 years+ - NCT03848962Recruiting
Share leftover or collected samples for research
This study helps collect and share human samples (like blood or other specimens) so researchers can do new studies. It’s mainly about providing samples for research use, not testing a treatment on you.
Lexington, MassachusettsAges 1 month–89 years - NCT06141434Recruiting
Maternal Exposures and Baby Diabetes Risk Study
This study follows pregnant women and their babies to learn how early-life factors may affect the risk of type 1 diabetes. If your baby has a parent or sibling with type 1 diabetes, you may be able to join.
Boston, MassachusettsAges birth–99 years - NCT05952583Recruiting
Study of growth-restricted twin babies in shared placenta
This study looks at babies in monochorionic (shared-placenta) twin pregnancies where one or both babies are growing too slowly. It aims to better understand this condition and follow families over time to improve care, with check-ins through age 2 after birth.
Boston, MassachusettsAges 18–50 - NCT06056635Recruiting
Study of special telescopes for fetal surgery
This study tests two types of small cameras (fetoscopes) to see how well they work for surgery on a baby before birth. Doctors want to learn if these tools can safely perform fetal procedures.
Boston, MassachusettsAges 18–45 - NCT07467694Recruiting
Postnatal exercise to activate baby's brown fat
This trial tests if exercise after childbirth can activate your baby's brown fat, which helps with metabolism. It may benefit mothers and their healthy, full-term babies.
Boston, MassachusettsAges 18–45 - NCT07312227Recruiting
Pregnancy at high altitude study
This study follows pregnant women living at high altitude in Bolivia to understand how pregnancy differs from those at sea level. It may help improve care for mothers and babies in high-altitude regions.
Boston, MassachusettsAges 18–45 - NCT07041281RecruitingPhase 2
Spironolactone to improve postpartum blood pressure after pregnancy hypertension
This study tests whether the medication spironolactone can help manage high blood pressure after delivery in people who had gestational hypertension or preeclampsia. It may help prevent long-term heart problems.
Boston, MassachusettsAges 18 years+ - NCT06866405RecruitingPhase 3
RSV vaccine boost in a new pregnancy
This study tests whether a second dose of the RSV vaccine during a new pregnancy protects you and your baby from RSV. If you received the RSVpreF or Abrysvo vaccine in a past pregnancy, you may be able to join.
Boston, MassachusettsAges birth+ - NCT06557005Recruiting
Helping new mothers with chronic conditions get primary care
This study helps new mothers with chronic health conditions transition smoothly from pregnancy care to regular primary care. If you have high blood pressure, diabetes, severe obesity, depression, or anxiety, you may be able to join a program that coordinates your care after childbirth.
Boston, MassachusettsAges 18 years+ - NCT06445946RecruitingPhase 4
Metformin vs insulin for gestational diabetes
This study compares two common medicines (metformin pills and insulin shots) to see which works better for controlling blood sugar in pregnant women with gestational diabetes. The goal is to find the best treatment for both mom and baby, now and in the long term.
Boston, MassachusettsAges 18 years+ - NCT04229043Recruiting
Test drink timing to study stomach emptying in late labor
This study measures how quickly a pregnant person’s stomach empties a water or sports drink during late labor. It may help improve safety and timing of what people can drink when labor is starting or being induced.
Boston, MassachusettsAges 18–50 - NCT01246765Recruiting
Pregnancy medication registry for mental health medicines
This study helps track how psychiatric (mental health) medicines affect pregnancy outcomes by collecting phone interviews during pregnancy. If you are pregnant and take (or have taken) mental health medication, you may help doctors understand risks and benefits better.
Boston, MassachusettsAges 18–45 - NCT05912517RecruitingPhase 3
Nipocalimab for high-risk pregnancy blood disease
This Phase 3 trial tests nipocalimab (an antibody medicine) to help prevent severe blood breakdown in a baby when a parent has certain blood antibodies. It enrolls people who previously had severe hemolytic disease in a past pregnancy and who are currently early in pregnancy with the same risk antibodies.
Boston, MassachusettsAges 18–45 - NCT05910580Recruiting
Screening and support for alcohol and substance risk in adults
This study aims to improve care access and outcomes for adults who screen positive for risky alcohol or drug use. If you qualify, you may be offered ways to connect to support during your reproductive years.
Boston, MassachusettsAges 18 years+ - NCT05789758Recruiting
Study of Spinraza in pregnancy for 5q spinal muscular atrophy
This study looks at how Spinraza (nusinersen) taken during or before pregnancy affects people with 5q spinal muscular atrophy (SMA) and the health of their babies. It mainly fits those who were pregnant and received Spinraza around the time of conception or during pregnancy.
Cambridge, MassachusettsAges 18–54
Pregnancy trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting pregnancy studies listed above.
- Massachusetts General Hospital · 5 studies
- Boston Children's Hospital · 4 studies
- Beth Israel Deaconess Medical Center · 3 studies
- Tufts Medical Center · 3 studies
- Joslin Diabetes Center · 2 studies
- Research Site · 2 studies
- University of Massachusetts Memorial Medical Center · 2 studies
- Beth Isreal Deaconess Medical Center
What taking part in a pregnancy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pregnancy trials in other states
Common questions
- Are there pregnancy clinical trials in Massachusetts?
- Yes. We're currently tracking 31 recruiting pregnancy studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pregnancy study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pregnancy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pregnancy studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.