Clinical trials · Pennsylvania
Pregnancy clinical trials in Pennsylvania
We’re tracking 42 recruiting pregnancy studies with a site in Pennsylvania — including Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06281665RecruitingPhase 4
Aspirin after preeclampsia: the TAP trial
This trial tests whether taking low-dose aspirin after giving birth can help people who had preeclampsia. It aims to see if aspirin can lower the risk of future heart problems.
Pittsburgh, PennsylvaniaAges 18–55 - NCT07469605Recruiting
Hysteroscopy to find and treat unknown pregnancy location
This study uses a scope placed in the uterus to find and treat a pregnancy that can't be located on ultrasound. It may help women with slow-rising pregnancy hormone levels find out where the pregnancy is and get treatment at the same time.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05444283Recruiting
Genetic testing to understand repeat pregnancy loss causes
This study looks for genetic clues in ongoing and past pregnancies to help explain why some people miscarry repeatedly. The results may help doctors better predict and prevent future pregnancy loss.
Hershey, PennsylvaniaAges 18–50 - NCT06957028Recruiting
CGM for early detection of high blood sugar in pregnancy
This study is testing whether wearing a continuous glucose monitor (CGM) early in pregnancy can help find and manage high blood sugar, which may lower the risk of problems for you and your baby. You would wear a small sensor under your skin, and the device sends information to a smartphone app.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04278651RecruitingPhase 4
Early support to treat iron-deficiency anemia in pregnancy
This trial tests whether starting treatment early in pregnancy can improve iron-deficiency anemia. You may be offered study medications and will be monitored to see if your blood counts and symptoms improve.
Philadelphia, PennsylvaniaAges 18–65 - NCT05264779Recruiting
Decision help tool for very early delivery planning
This study tests a decision-support tool (a structured way to guide conversations) for parents facing a high risk of delivering very early (about 22–26 weeks). It may help you and your baby’s care team make clearer, more aligned choices about neonatal (newborn) treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05450978Recruiting
Study drug levels in epilepsy meds during pregnancy and breastfeeding
This study measures how much epilepsy medicine (lamotrigine, levetiracetam, or oxcarbazepine) your body absorbs during pregnancy and breastfeeding. It may help doctors better understand dosing and safety during these times.
Pittsburgh, PennsylvaniaAges 18–45 - NCT05942313Recruiting
Predicting and preventing problems from opioid use during pregnancy
This study looks at ways to predict and reduce harmful outcomes for pregnant people with opioid use disorder (OUD) and their babies. It focuses on people who are already receiving ongoing medication treatment during pregnancy and will follow them around delivery at a specific hospital.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06408181RecruitingPhase 3
Aspirin to prevent pregnancy loss and preeclampsia
This study tests whether taking a daily low-dose aspirin can help prevent pregnancy loss and preeclampsia. It's for women who are in early pregnancy and have certain health risks.
Philadelphia, PennsylvaniaAges 18–45 - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Pittsburgh, PennsylvaniaAges 14–35 - NCT06535789RecruitingPhase 2/Phase 3
Inhaled insulin vs injections for gestational diabetes
This trial compares an inhaled insulin (Afrezza) to insulin injections for managing blood sugar after meals in women with gestational diabetes. The goal is to see if the inhaled option works as well and is easier to use.
Philadelphia, PennsylvaniaAges 18–40 - NCT06628453Recruiting
Continuous glucose monitor for type 2 diabetes in pregnancy
This study tests whether using a CGM (a small sensor that tracks blood sugar) can help manage type 2 diabetes during pregnancy better than standard care. It is for women who have type 2 diabetes and are pregnant with one baby.
Philadelphia, PennsylvaniaAges 18–50 - NCT07184775Recruiting
CGM vs finger-stick for type 2 diabetes in pregnancy
This trial tests if using a continuous glucose monitor (CGM) helps manage blood sugar better than finger-stick checks in pregnant women with type 2 diabetes. It aims to see if CGM leads to better sugar control and possibly healthier outcomes for you and your baby.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07197892Recruiting
AI platform for early pregnancy city-wide recruitment
This study tests a new conversational AI tool to help connect people in early pregnancy with city-wide care resources. If you are in early pregnancy and have a mobile phone, this trial may help improve how pregnancy care is offered.
Philadelphia, PennsylvaniaAges 15 years+ - NCT05912517RecruitingPhase 3
Nipocalimab for high-risk pregnancy blood disease
This Phase 3 trial tests nipocalimab (an antibody medicine) to help prevent severe blood breakdown in a baby when a parent has certain blood antibodies. It enrolls people who previously had severe hemolytic disease in a past pregnancy and who are currently early in pregnancy with the same risk antibodies.
Allentown, PennsylvaniaAges 18–45 - NCT07541469Recruiting
Safety Registry for Rezdiffra Use During Pregnancy and Breastfeeding
This registry collects information about the safety of a liver disease medication called Rezdiffra (resmetirom) when used during pregnancy or while breastfeeding. Researchers want to understand if the medication affects the health of pregnant women, babies, and nursing infants.
West Conshohocken, PennsylvaniaAges Any age - NCT07046845Recruiting
Prenatal Vitamin Study: Special vs. Generic for Moms with Food Insecurity
This study compares a special prenatal vitamin (Perelel) with a standard generic prenatal vitamin. It looks at how each affects the health of moms and babies, especially for those who have trouble getting enough nutritious food.
Pittsburgh, PennsylvaniaAges 14 years+ - NCT07599579Recruiting
Mobile app to manage high blood pressure after pregnancy complications
This study tests a smartphone app to help women who had high blood pressure during pregnancy manage their blood pressure now, 10–20 years later. The goal is to see if the app helps keep blood pressure under control and reduces heart disease risk.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03923374Recruiting
Study of buprenorphine for opioid use during pregnancy
This study looks at pregnancy and baby outcomes for people who are pregnant and taking buprenorphine for opioid use disorder. It may help doctors understand what to expect long-term for both parent and child when opioid treatment continues during pregnancy.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06415994Enrolling by invitation
Placental imaging and outcomes in opioid use disorder in pregnancy
This study looks at how the placenta and baby's development may be affected when a mother takes buprenorphine or methadone for opioid use disorder during pregnancy. It aims to find better ways to monitor health and improve outcomes for both mothers and babies.
Pittsburgh, PennsylvaniaAges 18–100 - NCT04146376Recruiting
Study of medicines for Von Willebrand disease during pregnancy
This study looks at how well a Von Willebrand disease treatment plan works during pregnancy, and whether some patients need extra “adjusting” of medicine. It may help prevent bleeding problems by matching treatment to each person’s lab results later in pregnancy.
Hershey, PennsylvaniaAges 18 years+ - NCT04252066Recruiting
Pregnancy and breastfeeding study for women with Fabry disease
This study follows pregnant and breastfeeding women with Fabry disease (and their infants) to better understand what happens during pregnancy and early life. You may or may not be taking migalastat, and the goal is to gather real-world information that could help future care.
Philadelphia, PennsylvaniaAges Any age - NCT04843111Recruiting
Registry study for pregnancy exposure to MenQuadfi vaccine
This is an observational registry that collects information about pregnant people and their babies when MenQuadfi® (a meningitis vaccine) was given during pregnancy or shortly before pregnancy. It helps researchers understand what happens to women and offspring after this vaccine exposure.
Swiftwater, PennsylvaniaAges Any age - NCT04939012Recruiting
MyPath tool to help postpartum women plan next pregnancy
This study tests a patient-centered tool (MyPath) that supports reproductive planning for women with substance use disorder during late pregnancy and right after delivery. The goal is to improve how you get guidance about future pregnancy choices and care.
Pittsburgh, PennsylvaniaAges 18 years+
Pregnancy trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting pregnancy studies listed above.
- University of Pennsylvania · 6 studies
- Magee-Womens Hospital of UPMC · 5 studies
- Pennsylvania State University · 2 studies
- Thomas Jefferson University Hospital · 2 studies
- University of Pittsburgh · 2 studies
- Investigative Site
- Lehigh Valley Hospital-Cedar Crest
- Madrigal Pharmaceuticals
What taking part in a pregnancy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pregnancy trials in other states
Common questions
- Are there pregnancy clinical trials in Pennsylvania?
- Yes. We're currently tracking 42 recruiting pregnancy studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pregnancy study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pregnancy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pregnancy studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.