Clinical trials
Preterm Birth clinical trials
Below are recruiting preterm birth clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04777760Recruiting
Surfactant treatment for newborn breathing distress
This trial looks at giving a “surfactant” medicine (a substance that helps keep baby lungs open) to newborns who have serious breathing problems soon after birth. It may help babies with neonatal respiratory distress or acute breathing distress, especially if they’re treated in the early time window.
Chongqing, Chongqing MunicipalityAges 1 minute–1 day - NCT05012072Recruiting
Lifestyle coaching to lower pregnancy stress and risk
This study tests a lifestyle coaching program to help reduce stress and improve emotional wellbeing during pregnancy. It may help lower risks for the baby by supporting healthier daily routines and mental health.
Webster, TexasAges 18–45 - NCT05934318Recruiting
Arginine supplements to help prevent pregnancy complications
This study tests whether taking an arginine-based supplement during pregnancy can help lower the risk of bad pregnancy outcomes. You may be eligible if you are pregnant in the early-to-mid period and meet safety and location requirements.
KisumuAges 16–40 - NCT05942924Recruiting
NEU-STIM for breathing support in very premature newborns
This trial studies whether NEU-STIM can help support breathing and oxygen levels in babies born very early. If your baby is born before 32 weeks, the study may include them after you provide consent.
GrazAges Up to 7 months - NCT06122506Recruiting
Laparoscopic vs vaginal cerclage to prevent early birth
This trial compares two types of surgery (one done through small cuts in the belly, one done through the vagina) to place a stitch around the cervix and prevent preterm birth. It may be a good option if you and your doctor are unsure which approach is best for you.
Aarhus NAges 18 years+ - NCT06264973Recruiting
Corticosteroids during pregnancy: how they work for mother and baby
This study looks at how corticosteroids (medicines given to help a baby's lungs mature) move through the mother's body and affect the baby during pregnancy. It aims to find the best dose and timing for mothers at risk of preterm birth.
Rotterdam, South HollandAges 18 years+ - NCT06462638Recruiting
Contact and relationship in the NICU for preterm babies
This study looks at how contact and relationship-building between parents and their babies in the neonatal intensive care unit (NICU) can help. It is for babies born a bit early (33–36 weeks) who are now stable, and for their parents under 50.
MessinaAges 18–50 - NCT06463652Recruiting
Cervical stitch with progesterone for short cervix
This trial tests whether adding a cervical stitch (cerclage) to progesterone treatment helps prevent early birth better than progesterone alone in women with a short cervix.
Ho Chi Minh City, Ho Chi Minh CityAges 18 years+ - NCT05703425RecruitingPhase 2
Sulfasalazine in pregnancy to change stress hormone levels
This Phase 2 study tests whether sulfasalazine, a medicine taken by mouth, can lower a pregnancy stress hormone called CRH in pregnant people. It’s aimed at people at higher risk for preterm birth, to see if the hormone change might be helpful.
New Brunswick, New JerseyAges 18 years+ - NCT06500910Recruiting
Exercise for heart and brain health in premature children
This study tests whether a supervised exercise program can help children born prematurely (before 32 weeks) improve their heart health and thinking skills. It's designed for children ages 6 to 12 who are otherwise healthy and not receiving special education for attention problems.
Basel, Canton of Basel-CityAges 6–12 - NCT06563726Recruiting
Sodium awareness study for breastfeeding moms of preemies
This study looks at whether tracking sodium levels in breast milk can help mothers of preterm babies improve their milk supply. If you are a new mom who gave birth before 35 weeks and plan to pump for at least two weeks, this trial may help you learn more about your milk.
Seattle, WashingtonAges Any age - NCT06723392RecruitingPhase 3
Treating bladder bacteria in pregnancy to prevent infections
This trial tests if a common antibiotic can safely treat bacteria in the urine of pregnant women who have no symptoms, to see if it prevents later infections. It focuses on women in low- and middle-income countries.
Dhaka, BangladeshAges 18–49 - NCT06822647Recruiting
Study on best timing for cervical length ultrasound during pregnancy
This study looks at the best time to measure the length of the cervix during a standard anatomy ultrasound. A shorter cervix can be a sign of early labor risk, so finding out the right moment to check may help improve care.
Detroit, MichiganAges Any age - NCT06826859RecruitingPhase 1/Phase 2
Daily aspirin vs split dosing to prevent preeclampsia
This study compares taking a daily low-dose aspirin (a single pill) versus splitting the same dose into two smaller pills many hours apart to see which way better prevents preeclampsia in pregnant people who are at higher risk.
Philadelphia, PennsylvaniaAges 16–55 - NCT07025954Recruiting
Delivery at 36 vs. 37 weeks for placenta previa with accreta
This trial compares delivering at 36 weeks versus 37 weeks for pregnant women with a condition called placenta previa with accreta, where the placenta covers the cervix and grows too deeply into the womb. The goal is to find the best time for delivery to improve safety for both mother and baby.
Guangzhou, GuangdongAges 18–45 - NCT07458802Recruiting
Routine STI screening in early pregnancy
This study checks if routine testing for sexually transmitted infections (STIs) during early pregnancy can improve health for you and your baby. Participation involves a simple screening test at your first prenatal visit.
GaboroneAges 15 years+ - NCT02744365Recruiting
Pregnancy complications biobank for future research
This study collects pregnancy-related samples and health information to help researchers learn more about conditions like preeclampsia and prematurity. Your participation may help future studies, but it usually involves whether you can safely consent and whether the pregnancy is continuing at the time of recruitment.
QuébecAges 18 years+ - NCT07072104Enrolling by invitation
Using MRI to Find Early Signs of Dyslexia in Children
This study uses MRI scans to find early signs of reading difficulties (dyslexia) in children ages 6 to 9, without needing them to read during the test. It aims to help identify children at risk before reading problems become obvious.
Milan, MIAges 6–9 - NCT06875401Enrolling by invitation
Long-term health after abdominal cerclage for preterm birth prevention
This study looks at how women who had an abdominal cerclage are doing in the long term. It aims to understand their health and well-being after this procedure to prevent early delivery.
Aarhus NAges 18 years+ - NCT06616012Enrolling by invitation
Oxygen monitor for sick newborns with umbilical catheters
This study tests a special sensor that can be placed inside the umbilical catheter to keep a constant watch on oxygen levels in critically ill newborns. It may help doctors make faster and more informed decisions without extra blood draws.
Gothenburg, Halland CountyAges birth–1 day - NCT06582147Enrolling by invitation
Social needs screening and support for NICU families
This study screens families of premature babies for social needs (like housing or food) and connects them to community resources. It aims to help mothers and their babies get the support they need after leaving the NICU.
Denver, ColoradoAges 18 years+ - NCT06385366Enrolling by invitation
Using early blood test to predict pregnancy complications
This study looks at a blood test done early in pregnancy (NIPT) to see if it can help predict conditions like preeclampsia, preterm labor, or gestational diabetes. If you had this test and had a healthy pregnancy or one of these complications, you may be able to join.
Ho Chi Minh City, Hồ Chí MinhAges 18–80 - NCT06794164Recruiting
Immediate skin-to-skin care for preterm babies at birth
This study tests if immediate skin-to-skin contact (holding your baby directly on your chest) right after birth helps preterm babies born between 26 and 32 weeks. Your baby might be placed on your skin while still in the delivery room, which could improve their breathing and temperature and help you bond.
Graz, StyriaAges birth–30 minutes - NCT04856501Recruiting
Parenting support for preterm toddlers’ brain and self-control
This study tests whether a responsive parenting program helps toddlers born early think, learn, and manage behavior more easily. It also checks whether families can complete toddler brain and behavior assessments (including brain scans).
Houston, TexasAges 1.3 years–2.5 years
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Common questions
- Are there clinical trials for preterm birth?
- Yes. Clin2 currently lists 90 recruiting preterm birth studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a preterm birth trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a preterm birth trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.