Clinical trials
Psychosis clinical trials
Below are recruiting psychosis clinical trials, each written for real people, not researchers. We’re tracking 146 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07231497RecruitingPhase 3
Cognitive training for early psychosis
This study tests whether a medication called modafinil can help improve thinking skills in people who have early psychosis. Participants will also do computer-based cognitive exercises. The goal is to see if combining the medication with training boosts memory, attention, and problem-solving.
Minneapolis, MinnesotaAges 18–35 - NCT07234708Recruiting
Feeling Safe Study for people with persecutory delusions
This study tests a psychological treatment for people with schizophrenia who feel unsafe because they believe others are trying to harm them. The goal is to help reduce these fears and improve daily life.
BarcelonaAges 18 years+ - NCT07213492Recruiting
Support program for young adults with bipolar disorder
This study tests a program to help young adults with a recent bipolar diagnosis move from hospital back to their community. You would get education sessions and support from peers to make the transition smoother.
Hamilton, OntarioAges 18–35 - NCT07196462Recruiting
Brain stimulation to reduce cannabis craving in schizophrenia
This study tests if a non-invasive brain stimulation technique can help reduce cravings for cannabis in people with schizophrenia. It aims to see if this approach can improve outcomes for those who use cannabis and have a psychotic disorder.
Nashville, TennesseeAges 18–65 - NCT07192042Recruiting
Testing a device to check sleep breathing in schizophrenia
This trial uses a non-wearable device to assess sleep-disordered breathing in people with schizophrenia who are hospitalized. It aims to understand if this easy method can help monitor sleep issues.
New Taipei CityAges 20–70 - NCT06958341Recruiting
Brain and nerve disease registry with optional fluid collection
This study collects extra fluid from a spinal tap to learn more about brain and nerve diseases. It may help find better treatments in the future.
Berlin, State of BerlinAges Any age - NCT07122531Recruiting
Recovery with ketones and antipsychotics
This trial tests whether adding a special drink with ketones can help people recover faster while taking antipsychotic medication for early psychosis. It may be a safe way to boost brain energy and reduce side effects.
Sherbrooke, QuebecAges 18–35 - NCT03601026Recruiting
Genetic counseling for youth using cannabis safely
This study offers genetic counseling to help reduce mental health problems that can happen for some young people who use cannabis. You join if you are already part of the FORBOW study and fit their age and mental-health criteria.
Halifax, Nova ScotiaAges 12–21 - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07091344Recruiting
VR-based therapy for voice hearing in schizophrenia
This study tests whether a virtual reality therapy that lets you talk to an avatar of the voice you hear can help reduce distress and improve thinking skills. It's for people with schizophrenia who hear voices regularly and are on stable medication.
Barcelona, CataloniaAges 18 years+ - NCT06978452Recruiting
Youth mental health: tracking development and outcomes
This study looks at how young people's mental health develops over time. It compares youth who have already sought help for mental health concerns with those who haven't, to better understand what helps or hinders well-being.
Montreal, QuebecAges 9–25 - NCT06978894Recruiting
Using speech to detect psychosis relapse early
This study tests whether changes in your speech patterns can help predict a psychotic relapse before it happens. If you're in an early psychosis program, you may help develop a tool that could warn you and your care team early.
London, OntarioAges 16 years+ - NCT07041463Recruiting
Support program for family caregivers of young people with first episode psychosis
This study tests a support program for family members caring for a young adult (18-35) who recently had a first episode of psychosis (within the last 6 months). The program is led by a specially trained nurse and aims to help caregivers better understand and support their loved one.
BoharsAges 18 years+ - NCT04366518RecruitingEarly Phase 1
Personalized brain-based treatment for frequent voice hallucinations
This early-phase study tests a personalized treatment plan for people who hear voices (auditory verbal hallucinations) at least weekly. It uses brain/machine-based information to try to better target hallucinations and monitor safety.
New Haven, ConnecticutAges 18–65 - NCT06939088RecruitingPhase 2
Tirzepatide for alcohol reduction in schizophrenia
This trial tests if tirzepatide, a once-weekly injection, can help reduce heavy drinking in people who have both schizophrenia and alcohol use disorder. If you struggle with alcohol and have stable schizophrenia, this study may offer a new treatment option.
Aalborg, DenmarkAges 18–70 - NCT06904079Recruiting
AI-based rehab study for serious mental disorders
This study uses computer analysis and AI to predict how people with severe mental disorders might recover and to suggest better support. It may help improve rehabilitation plans tailored to each person.
ShanghaiAges 18–65 - NCT06856161Recruiting
Blood test to help diagnose mental health conditions
This study is testing a new blood test that might help doctors better understand and diagnose conditions like depression, psychosis, or schizophrenia. If you are 19 or older and have one of these conditions, you may be able to join.
New Westminster, British ColumbiaAges 19 years+ - NCT05962216Recruiting
Real-world check of Rexulti for schizophrenia and depression
This study looks at how well brexpiprazole (Rexulti) works in everyday treatment, and how people feel and function over time. You may be eligible if you’re newly started on Rexulti and have a qualifying mental health diagnosis.
Hong KongAges 18–65 - NCT05550155Recruiting
TMS treatment to reduce voices in schizophrenia
This trial studies whether repeated noninvasive brain stimulation (TMS) can help reduce ongoing voice-hearing (auditory verbal hallucinations) in people with schizophrenia or schizoaffective disorder. It focuses on whether doing this after medication is already adjusted can improve symptoms and help keep them controlled.
CaenAges 18–65 - NCT06687694Recruiting
How antipsychotics affect the immune system in psychosis
This study looks at how antipsychotic medicines affect the immune system in people with psychosis. By taking blood samples before and after starting or changing medication, researchers hope to understand why some people respond better to treatment.
London, United KingdomAges 18–65 - NCT06649552Recruiting
French validation of a psychosis risk questionnaire for teens
This study is testing a new French version of a questionnaire (SPI-CY) that helps doctors better understand early signs of psychosis in teenagers. If you are 12 to 17 and already being checked for these signs, you may be able to help improve the tool.
LilleAges 12–17 - NCT06634641RecruitingPhase 4
Clozapine and immune function in Parkinson's disease
This trial tests whether clozapine, a medication for psychosis in Parkinson's disease, affects the immune system. It involves regular blood monitoring to help keep patients safe.
SalouëlAges 18 years+ - NCT06586164Recruiting
Rehabilitation research for veterans with serious mental illness
This study is testing a new rehabilitation program for veterans with serious mental illness, like schizophrenia, bipolar disorder, or PTSD. If you join, you will help researchers see if this program improves daily functioning and quality of life.
San Diego, CaliforniaAges 18–83 - NCT06585787RecruitingPhase 3
Testing KarXT for psychosis in Alzheimer’s disease
This study tests an investigational medication (KarXT) for treating psychosis—hallucinations or delusions—in people with Alzheimer’s disease. It aims to see if the drug can reduce these symptoms safely and effectively.
Chandler, ArizonaAges 55–90
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Common questions
- Are there clinical trials for psychosis?
- Yes. Clin2 currently lists 146 recruiting psychosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psychosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psychosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.