Clinical trials
Parkinson Disease Psychosis clinical trials
Below are recruiting parkinson disease psychosis clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05824728RecruitingPhase 2
Levetiracetam for Parkinson’s psychosis with study partner support
This Phase 2 study tests whether AGB101 (levetiracetam) can reduce hallucinations, delusions, or related symptoms in people with Parkinson’s disease psychosis, while checking safety. You and a study partner will help with dosing and regular check-ins, including MRI scans.
Baltimore, MarylandAges 40–85 - NCT04373317RecruitingPhase 4
Test pimavanserin vs quetiapine for Parkinson’s hallucinations or delusions
This study compares pimavanserin to quetiapine to treat hallucinations and/or delusions caused by Parkinson’s disease. It may help find which medicine works better and is easier to use for Parkinson’s psychosis.
Tucson, ArizonaAges 40 years+ - NCT05357612RecruitingPhase 4
PET scan study for brain serotonin in neurodegenerative diseases
This study uses a special PET brain scan tracer to better understand serotonin receptor activity in people with certain neurodegenerative conditions, especially when they develop hallucinations or delusions. The results may help researchers improve how these brain changes are measured and tracked over time.
Nashville, TennesseeAges 50–85 - NCT05568498RecruitingPhase 2
Probiotic trial for depression in Parkinson’s disease
This Phase 2 study tests whether taking probiotics can improve depression and mood symptoms in people with Parkinson’s disease. It’s meant for those with mild to moderate depression and stable Parkinson’s and mood treatments.
Vancouver, British ColumbiaAges 40–80 - NCT06634641RecruitingPhase 4
Clozapine and immune function in Parkinson's disease
This trial tests whether clozapine, a medication for psychosis in Parkinson's disease, affects the immune system. It involves regular blood monitoring to help keep patients safe.
SalouëlAges 18 years+ - NCT07207122Recruiting
Focused ultrasound for Parkinson's cognitive symptoms
This trial tests whether a non-invasive ultrasound treatment, called transcranial focused ultrasound stimulation (tFUS), can improve movement and thinking in people with Parkinson's disease. It may be an option for those whose symptoms are not well controlled by medication alone.
Tucson, ArizonaAges 22–80 - NCT07323121Recruiting
Flickering light therapy for sleep problems in Parkinson's
This study tests whether a special flickering light (40 Hz) can help improve sleep in people with Parkinson's disease. Participants will be exposed to the light at home, and researchers will track changes in sleep quality.
Nanjing, JiangsuAges 50–75 - NCT07151378RecruitingPhase 3
Intestinal gel for Parkinson's mood and behavior problems
This trial tests a gel form of levodopa (called Lecigon) given through a tube into the intestine to see if it helps reduce mood swings, impulsive behaviors, and other mental side effects in people with Parkinson's who already have motor fluctuations. It is for people who have had Parkinson's for at least 5 years and are between 18 and 75 years old.
Saarlouis, SaarlandAges 18–75 - NCT06386497Recruiting
Bed for better sleep in Parkinson's disease
This study tests a special bed (Somnomat Casa) to help improve sleep in people with Parkinson's disease. It looks at whether the bed is comfortable and acceptable to use.
BernAges 18–85 - NCT06629389RecruitingPhase 2
Cannabidiol (Kanbis) for Parkinson's symptoms
This trial tests whether cannabidiol (CBD) can help with Parkinson's disease symptoms. Researchers want to see if it's safe and effective for people with mild to moderate Parkinson's who are already on stable medications.
Mendoza, Mendoza ProvinceAges 40–80 - NCT07138560RecruitingPhase 4
Study of IPX-203 for Parkinson's disease (BOOST-PD)
This study tests a new formulation of carbidopa-levodopa (IPX-203) to see how well it works for people with Parkinson's disease. It uses a wearable device to measure movement and aims to improve “off” time, when symptoms return between doses.
Cleveland, OhioAges 40 years+ - NCT07404241Recruiting
Brain activity linked to movement and mood swings in Parkinson's
This study looks at brain signals related to motor and psychiatric changes in people with Parkinson's who are scheduled for deep brain stimulation (DBS) surgery. The goal is to better understand why symptoms fluctuate and how DBS may help.
GenevaAges 18–80 - NCT07536542Recruiting
Dual-Task Training for Hand and Arm Function in Parkinson's
This study tests whether doing hand and arm exercises while performing a second task (like counting or listening) can improve movement and strength in people with Parkinson's disease. The goal is to help you move more smoothly and regain function in your hands and arms.
AnkaraAges 40–65 - NCT06885138Enrolling by invitation
Testing brain stimulation for depression in Parkinson's disease
This trial tests if a gentle brain stimulation technique called tDCS can improve depression symptoms in people with Parkinson's disease. You'll receive either real or placebo stimulation over several sessions to see if it helps your mood.
MilanAges 35–75 - NCT06422208Enrolling by invitationPhase 1
Parkinson's cell transplant trial using your own cells
This trial tests whether transplanting special dopamine-producing cells made from a patient's own skin cells can help treat Parkinson's disease. It is for people who have had Parkinson's for at least 5 years and still respond well to medication.
Boston, MassachusettsAges 55–80 - NCT05779475Enrolling by invitation
Study of people with moderate Parkinson’s disease
This is an observational study, meaning it doesn’t test a new drug—researchers mainly follow people to better understand moderate Parkinson’s disease and who may be good candidates for future cell therapy. If you have moderate symptoms that aren’t well controlled with tablets, this study may help inform better future treatments.
Irvine, CaliforniaAges 50–68 - NCT05504902Enrolling by invitation
Device training for advanced Parkinson’s using touch feedback
This study tests whether coordinated touch (vibrotactile) training can improve symptoms in people with Parkinson’s. You may be asked to use a special device and attend virtual check-ins, with some visits requiring stopping Parkinson’s meds for short periods.
Stanford, CaliforniaAges 18 years+ - NCT06982638Recruiting
Speeding up walking in Parkinson's with brain stimulation
This trial tests if a special type of brain stimulation (called TMS) can help people with Parkinson's disease who experience freezing of gait—when your feet feel stuck to the floor. The goal is to see if this treatment can improve walking and reduce those freezing episodes.
Charleston, South CarolinaAges 50–80 - NCT05576818RecruitingPhase 3
Synbiotic add-on for people with Parkinson’s disease
This trial tests whether adding a synbiotic (a mix of probiotics and prebiotics) along with standard Parkinson’s medicines can improve symptoms or health outcomes. It’s mainly for adults with Parkinson’s disease at earlier to mid-stages who take dopamine replacement therapy.
Tanta, El GharbiaAges 45–65 - NCT06231563RecruitingPhase 2
Ketamine for depression in veterans with Parkinson's
This study tests if ketamine can help treat depression in veterans with Parkinson's disease. It involves several in-person and remote visits, and you will need to avoid certain medications and cannabis for a short time before and during some visits.
San Francisco, CaliforniaAges 40–80 - NCT07064005RecruitingPhase 1
Boosting glutathione with a supplement in Parkinson's
This study tests whether a supplement called gamma-glutamylcysteine can increase levels of a natural antioxidant called glutathione in the brain of people with Parkinson's. If you are between 50 and 80 and have mild cognitive symptoms, this trial may help researchers understand a new way to support brain health.
Pittsburgh, PennsylvaniaAges 50–80 - NCT06688968Recruiting
Music, thinking, and memory in Parkinson's and Alzheimer's
This study looks at how music engagement affects thinking and memory in people with Parkinson's or Alzheimer's disease. It may help researchers understand how music can support brain health as we age.
Montpellier, HéraultAges 60 years+ - NCT07316296RecruitingPhase 3
Testing a drug to reduce freezing of gait in Parkinson's
This trial tests whether atomoxetine, a drug that boosts a brain chemical called noradrenaline, can help reduce freezing of gait—a feeling of your feet being stuck to the ground—in people with Parkinson's disease. You would continue your usual Parkinson's medications during the study and undergo walking tests and brain scans to see if the drug helps.
Nijmegen, GelderlandAges 18 years+ - NCT07461220RecruitingPhase 1/Phase 2
Testing IRL757 for apathy in Parkinson's disease
This trial tests a new drug called IRL757 to see if it is safe and helps with apathy (loss of motivation or interest) in people with Parkinson's disease. You need to have at least moderate apathy and a caregiver who can come to visits with you.
PlevenAges 50–90
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Common questions
- Are there clinical trials for parkinson disease psychosis?
- Yes. Clin2 currently lists 44 recruiting parkinson disease psychosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease psychosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease psychosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.