Clinical trials
Psychosis clinical trials
Below are recruiting psychosis clinical trials, each written for real people, not researchers. We’re tracking 146 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06585787RecruitingPhase 3
Testing KarXT for psychosis in Alzheimer’s disease
This study tests an investigational medication (KarXT) for treating psychosis—hallucinations or delusions—in people with Alzheimer’s disease. It aims to see if the drug can reduce these symptoms safely and effectively.
Chandler, ArizonaAges 55–90 - NCT06729671Recruiting
Probiotics for antipsychotic-related metabolic issues
This trial tests if a probiotic supplement can help reduce metabolic side effects (like weight gain or high blood sugar) caused by antipsychotic medications. It is for people with psychosis who are on stable treatment.
CorkAges 18–65 - NCT06856161Recruiting
Blood test to help diagnose mental health conditions
This study is testing a new blood test that might help doctors better understand and diagnose conditions like depression, psychosis, or schizophrenia. If you are 19 or older and have one of these conditions, you may be able to join.
New Westminster, British ColumbiaAges 19 years+ - NCT06904079Recruiting
AI-based rehab study for serious mental disorders
This study uses computer analysis and AI to predict how people with severe mental disorders might recover and to suggest better support. It may help improve rehabilitation plans tailored to each person.
ShanghaiAges 18–65 - NCT06939088RecruitingPhase 2
Tirzepatide for alcohol reduction in schizophrenia
This trial tests if tirzepatide, a once-weekly injection, can help reduce heavy drinking in people who have both schizophrenia and alcohol use disorder. If you struggle with alcohol and have stable schizophrenia, this study may offer a new treatment option.
Aalborg, DenmarkAges 18–70 - NCT06958341Recruiting
Brain and nerve disease registry with optional fluid collection
This study collects extra fluid from a spinal tap to learn more about brain and nerve diseases. It may help find better treatments in the future.
Berlin, State of BerlinAges Any age - NCT06978452Recruiting
Youth mental health: tracking development and outcomes
This study looks at how young people's mental health develops over time. It compares youth who have already sought help for mental health concerns with those who haven't, to better understand what helps or hinders well-being.
Montreal, QuebecAges 9–25 - NCT06978894Recruiting
Using speech to detect psychosis relapse early
This study tests whether changes in your speech patterns can help predict a psychotic relapse before it happens. If you're in an early psychosis program, you may help develop a tool that could warn you and your care team early.
London, OntarioAges 16 years+ - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07091344Recruiting
VR-based therapy for voice hearing in schizophrenia
This study tests whether a virtual reality therapy that lets you talk to an avatar of the voice you hear can help reduce distress and improve thinking skills. It's for people with schizophrenia who hear voices regularly and are on stable medication.
Barcelona, CataloniaAges 18 years+ - NCT07122531Recruiting
Recovery with ketones and antipsychotics
This trial tests whether adding a special drink with ketones can help people recover faster while taking antipsychotic medication for early psychosis. It may be a safe way to boost brain energy and reduce side effects.
Sherbrooke, QuebecAges 18–35 - NCT07192042Recruiting
Testing a device to check sleep breathing in schizophrenia
This trial uses a non-wearable device to assess sleep-disordered breathing in people with schizophrenia who are hospitalized. It aims to understand if this easy method can help monitor sleep issues.
New Taipei CityAges 20–70 - NCT07196462Recruiting
Brain stimulation to reduce cannabis craving in schizophrenia
This study tests if a non-invasive brain stimulation technique can help reduce cravings for cannabis in people with schizophrenia. It aims to see if this approach can improve outcomes for those who use cannabis and have a psychotic disorder.
Nashville, TennesseeAges 18–65 - NCT07213492Recruiting
Support program for young adults with bipolar disorder
This study tests a program to help young adults with a recent bipolar diagnosis move from hospital back to their community. You would get education sessions and support from peers to make the transition smoother.
Hamilton, OntarioAges 18–35 - NCT07230652RecruitingPhase 1
Safety study of LY03020 for healthy volunteers and people with schizophrenia
This study tests the safety of a new medication called LY03020. It is for healthy volunteers and for people with stable schizophrenia. The study aims to see how well the body handles the drug and what side effects might occur.
BeijingAges 18–60 - NCT07231497RecruitingPhase 3
Cognitive training for early psychosis
This study tests whether a medication called modafinil can help improve thinking skills in people who have early psychosis. Participants will also do computer-based cognitive exercises. The goal is to see if combining the medication with training boosts memory, attention, and problem-solving.
Minneapolis, MinnesotaAges 18–35 - NCT07234708Recruiting
Feeling Safe Study for people with persecutory delusions
This study tests a psychological treatment for people with schizophrenia who feel unsafe because they believe others are trying to harm them. The goal is to help reduce these fears and improve daily life.
BarcelonaAges 18 years+ - NCT07395206Recruiting
Kiso Mind App for schizophrenia or schizoaffective disorder
This study tests the Kiso Mind app, a smartphone app designed to help people with schizophrenia or schizoaffective disorder manage their symptoms. It looks at whether the app is easy to use and helpful for daily life.
Berlin, State of BerlinAges 18–65 - NCT01409109Recruiting
Study database for brain signal markers in psychosis
This study builds a database of brain-signal measurements to help find “biomarkers” that may point to schizophrenia or related mental illnesses. Depending on whether you have a mental health diagnosis or you’re healthy, the study will collect information and brain data to compare groups.
Dallas, TexasAges 18–60 - NCT07397975Recruiting
Using speech to predict relapse in psychosis
This study uses speech recordings from a smartphone app to see if changes in the way you talk can predict when someone might have a relapse of psychosis. It is for people who are currently stable or for healthy volunteers to compare.
KlecanyAges 18–65 - NCT07483294RecruitingPhase 4
Brain imaging study for first-episode psychosis treatment
This study uses brain scans to find markers that can predict how well antipsychotic medications work in people having their first episode of psychosis. It aims to help doctors choose the right treatment earlier.
Glen Oaks, New YorkAges 15–40 - NCT07499934Recruiting
Mindfulness experience for young people at risk of psychosis
This study explores how young people who are at high risk for psychosis or have had a first episode experience mindfulness. It uses interviews to understand their personal experience, which could help improve future treatments.
LaxouAges 15–30 - NCT07569471Recruiting
Group compassion therapy for psychosis beliefs
This study tests a new group-based therapy that combines compassion-focused techniques with cognitive behavioral therapy to help people with schizophrenia or related conditions change their beliefs about their psychosis. The goal is to reduce distress and improve how you cope with symptoms.
Scarborough Village, OntarioAges 18 years+ - NCT07616999Recruiting
Long-term follow-up study of early psychosis treatment
This study follows people who were part of an earlier research trial about medication management during their first psychotic episode. Researchers want to understand how those early treatment choices affected their recovery over the past 20 years.
Hong KongAges 18–65
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Common questions
- Are there clinical trials for psychosis?
- Yes. Clin2 currently lists 146 recruiting psychosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psychosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psychosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.