Clinical trials
Psychosis clinical trials
Below are recruiting psychosis clinical trials, each written for real people, not researchers. We’re tracking 146 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06482554RecruitingPhase 3
Lumateperone for Apathy in Psychotic Disorders
This trial tests a medication called lumateperone to see if it can improve apathy (lack of motivation) in people who have psychotic symptoms from schizophrenia or related disorders. It may help if you are already on a stable treatment but still struggle with apathy.
Shreveport, LouisianaAges 18–65 - NCT05703711Recruiting
MHealth plus nurse care for mental health in West Africa
This trial tests whether combining phone-based support (mHealth) with regular nurse-delivered care can improve outcomes for people with serious mental illness. You might benefit if you’re currently in an inpatient prayer camp and living with psychosis, mania, or depression.
AccraAges 18 years+ - NCT07713849Recruiting
Transition care for recent psychosis
This study tests a program to help people recently diagnosed with psychosis (within the last two years) transition from hospital to community care. If you have a psychotic disorder and a caregiver involved in your discharge planning, this could help you.
Chicago, IllinoisAges 18–40 - NCT07703670Recruiting
MicroRNA markers in first episode schizophrenia
This study looks at tiny molecules called microRNAs in the blood of people having their first episode of schizophrenia. It aims to find markers that could help guide treatment choices.
Glen Oaks, New YorkAges 15–40 - NCT07645443Recruiting
Mindfulness group therapy for young adults with early psychosis
This study tests whether a mindfulness-based group therapy program helps young adults who have recently experienced their first psychotic episode. You would participate in group sessions alongside your regular treatment to see if mindfulness can improve how you feel.
Mannheim, Baden-WurttembergAges 16–35 - NCT06341517Recruiting
Brain circuit therapy for schizophrenia
This trial tests a noninvasive brain stimulation treatment (TMS) to improve symptoms of schizophrenia. It aims to target brain circuits that may be out of balance.
GenevaAges 18–65 - NCT07616999Recruiting
Long-term follow-up study of early psychosis treatment
This study follows people who were part of an earlier research trial about medication management during their first psychotic episode. Researchers want to understand how those early treatment choices affected their recovery over the past 20 years.
Hong KongAges 18–65 - NCT05127278Recruiting
Testing a tool to spot early signs of new mental health problems
This study tests whether a new screening tool can detect emerging mental health problems at an early stage. It may help people and clinicians identify issues sooner, so support can happen earlier.
GlasgowAges 12–35 - NCT05995782RecruitingPhase 1
Testing safety of FB418 in healthy people
This trial studies a new drug called FB418 to see if it's safe and how the body handles it. It first tests single doses in younger healthy men, then multiple doses, and also includes an optional group for healthy older adults.
SeoulAges 19 years+ - NCT07569471Recruiting
Group compassion therapy for psychosis beliefs
This study tests a new group-based therapy that combines compassion-focused techniques with cognitive behavioral therapy to help people with schizophrenia or related conditions change their beliefs about their psychosis. The goal is to reduce distress and improve how you cope with symptoms.
Scarborough Village, OntarioAges 18 years+ - NCT06729671Recruiting
Probiotics for antipsychotic-related metabolic issues
This trial tests if a probiotic supplement can help reduce metabolic side effects (like weight gain or high blood sugar) caused by antipsychotic medications. It is for people with psychosis who are on stable treatment.
CorkAges 18–65 - NCT05728138Recruiting
Talk therapy trial for suicidal thoughts in early psychosis
This study tests a psychosocial (talk-based) intervention for people with early psychosis who are having thoughts about death or being better off dead. It aims to see if the approach is safe and workable, and whether it can help reduce suicidal thinking.
Karachi, SindhAges 18 years+ - NCT07499934Recruiting
Mindfulness experience for young people at risk of psychosis
This study explores how young people who are at high risk for psychosis or have had a first episode experience mindfulness. It uses interviews to understand their personal experience, which could help improve future treatments.
LaxouAges 15–30 - NCT07483294RecruitingPhase 4
Brain imaging study for first-episode psychosis treatment
This study uses brain scans to find markers that can predict how well antipsychotic medications work in people having their first episode of psychosis. It aims to help doctors choose the right treatment earlier.
Glen Oaks, New YorkAges 15–40 - NCT07470437Recruiting
Mouth matters: dental support for mental health
This trial tests whether a special dental support program can improve oral health for adults receiving mental health care in the community. It's for people who haven't seen a dentist in a while and want to get help with their dental care.
Preston, LancashireAges 18 years+ - NCT07459244Recruiting
ECG changes in people who use methamphetamine
This study looks at the electrical activity of the heart (ECG) in people who use methamphetamine, including those who develop psychosis from it. It compares them to healthy volunteers to see if methamphetamine affects heart function.
Elâzığ, ElâzığAges 18–65 - NCT06802952Recruiting
Personalized magnetic brain stimulation for early psychosis risk
This study tests whether a type of magnetic brain stimulation (rTMS) can help people who are at high risk for psychosis. The stimulation is personalized using a brain scan called magnetoencephalography (MEG) to target the right areas.
ShanghaiAges 13–35 - NCT07397975Recruiting
Using speech to predict relapse in psychosis
This study uses speech recordings from a smartphone app to see if changes in the way you talk can predict when someone might have a relapse of psychosis. It is for people who are currently stable or for healthy volunteers to compare.
KlecanyAges 18–65 - NCT07395206Recruiting
Kiso Mind App for schizophrenia or schizoaffective disorder
This study tests the Kiso Mind app, a smartphone app designed to help people with schizophrenia or schizoaffective disorder manage their symptoms. It looks at whether the app is easy to use and helpful for daily life.
Berlin, State of BerlinAges 18–65 - NCT07387705Recruiting
Wellness program for early psychosis care
This study tests a wellness program for people receiving care at a first-episode psychosis clinic. It aims to see if the program helps improve health and well-being.
Chicago, IllinoisAges Any age - NCT06508450Recruiting
Mental health support for minority young adults
This trial tests a program to help racial and ethnic minority young adults engage with mental health services. It aims to improve access and participation in care.
The Bronx, New YorkAges 18–34 - NCT07276321Recruiting
Mobile app support for psychosis symptoms in Ghana
This study tests a mobile app to help people with psychosis symptoms manage their condition. It aims to see if the app is helpful for people receiving care at a psychiatric hospital.
AccraAges 18 years+ - NCT07252206Recruiting
Culturally adapted CBT for Black people with psychosis
This study offers a talking therapy called culturally adapted cognitive behavioral therapy for psychosis (CBTp) for Black people in the UK who have schizophrenia or related conditions. It aims to see if this approach is helpful and acceptable, and you may join if you are over 16, identify with a Black background, and are not in a current crisis.
ManchesterAges 16 years+ - NCT07230652RecruitingPhase 1
Safety study of LY03020 for healthy volunteers and people with schizophrenia
This study tests the safety of a new medication called LY03020. It is for healthy volunteers and for people with stable schizophrenia. The study aims to see how well the body handles the drug and what side effects might occur.
BeijingAges 18–60
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Common questions
- Are there clinical trials for psychosis?
- Yes. Clin2 currently lists 146 recruiting psychosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psychosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psychosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.