Clinical trials
Psychosis clinical trials
Below are recruiting psychosis clinical trials, each written for real people, not researchers. We’re tracking 145 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04004364Recruiting
Research study for people enrolled in a schizophrenia care program
This is an early-stage research study for people who are already enrolled in a specific schizophrenia care program. It aims to improve outcomes by testing practice changes within that program.
Lauderdale Lakes, FloridaAges 15–40 - NCT07041463Recruiting
Support program for family caregivers of young people with first episode psychosis
This study tests a support program for family members caring for a young adult (18-35) who recently had a first episode of psychosis (within the last 6 months). The program is led by a specially trained nurse and aims to help caregivers better understand and support their loved one.
BoharsAges 18 years+ - NCT05880719Recruiting
Music-based computer program for memory after first psychosis
This study tests whether using a computer-based music program can help improve memory and thinking in young people who have had their first episode of psychosis. Participants will work in small groups with the program to see if it helps their cognitive skills.
CaenAges 18–30 - NCT07459244Recruiting
ECG changes in people who use methamphetamine
This study looks at the electrical activity of the heart (ECG) in people who use methamphetamine, including those who develop psychosis from it. It compares them to healthy volunteers to see if methamphetamine affects heart function.
Elâzığ, ElâzığAges 18–65 - NCT04046497RecruitingPhase 4
Using AI to help track taking your mouth medication
This trial tests whether an artificial intelligence tool can measure how well people take their prescribed oral antipsychotic medicines. You may be able to take part if you are already in a community support program and you’ve been prescribed an oral antipsychotic.
Hialeah, FloridaAges 15–40 - NCT06582901Recruiting
Support for youth at clinical high risk for psychosis in Tunisia
This study tests a support program for young people in Tunisia who show early signs of possible psychosis. It aims to help them before more serious symptoms develop.
TunisAges 14–28 - NCT06802952Recruiting
Personalized magnetic brain stimulation for early psychosis risk
This study tests whether a type of magnetic brain stimulation (rTMS) can help people who are at high risk for psychosis. The stimulation is personalized using a brain scan called magnetoencephalography (MEG) to target the right areas.
ShanghaiAges 13–35 - NCT07470437Recruiting
Mouth matters: dental support for mental health
This trial tests whether a special dental support program can improve oral health for adults receiving mental health care in the community. It's for people who haven't seen a dentist in a while and want to get help with their dental care.
Preston, LancashireAges 18 years+ - NCT07713849Recruiting
Transition care for recent psychosis
This study tests a program to help people recently diagnosed with psychosis (within the last two years) transition from hospital to community care. If you have a psychotic disorder and a caregiver involved in your discharge planning, this could help you.
Chicago, IllinoisAges 18–40 - NCT05357612RecruitingPhase 4
PET scan study for brain serotonin in neurodegenerative diseases
This study uses a special PET brain scan tracer to better understand serotonin receptor activity in people with certain neurodegenerative conditions, especially when they develop hallucinations or delusions. The results may help researchers improve how these brain changes are measured and tracked over time.
Nashville, TennesseeAges 50–85 - NCT07645443Recruiting
Mindfulness group therapy for young adults with early psychosis
This study tests whether a mindfulness-based group therapy program helps young adults who have recently experienced their first psychotic episode. You would participate in group sessions alongside your regular treatment to see if mindfulness can improve how you feel.
Mannheim, Baden-WurttembergAges 16–35 - NCT03525054Recruiting
Brain-and-speech study after suicidal thoughts or actions
This study looks at how people use language (free speech) after a suicidal gesture, idea, or related behavior that affected their life. The researchers use computer-based analysis to understand patterns in speech and thinking, which may help improve support and assessment.
BrestAges 15–30 - NCT03601026Recruiting
Genetic counseling for youth using cannabis safely
This study offers genetic counseling to help reduce mental health problems that can happen for some young people who use cannabis. You join if you are already part of the FORBOW study and fit their age and mental-health criteria.
Halifax, Nova ScotiaAges 12–21 - NCT03906435Recruiting
Cognitive therapy to prevent problems for very premature NICU babies
This study offers a counseling approach to help prevent “Vulnerable Child Syndrome” in babies born very early and cared for in the NICU. It focuses on support during the early months after birth and compares outcomes for families getting the therapy versus usual support.
Dallas, TexasAges Any age - NCT07703670Recruiting
MicroRNA markers in first episode schizophrenia
This study looks at tiny molecules called microRNAs in the blood of people having their first episode of schizophrenia. It aims to find markers that could help guide treatment choices.
Glen Oaks, New YorkAges 15–40 - NCT04366518RecruitingEarly Phase 1
Personalized brain-based treatment for frequent voice hallucinations
This early-phase study tests a personalized treatment plan for people who hear voices (auditory verbal hallucinations) at least weekly. It uses brain/machine-based information to try to better target hallucinations and monitor safety.
New Haven, ConnecticutAges 18–65 - NCT04370730Recruiting
Study brain and symptoms in youth with early psychosis
This study looks at how psychosis symptoms and development change over time in children and teens. It may help doctors better understand different patterns of illness and how to support young people with these disorders.
GentillyAges 7–20 - NCT04945278Recruiting
Brain study of self-recognition in teens at mental risk
This study looks at how people recognize themselves and understand the difference between self and others. It may help researchers better understand brain processes in teens who are at higher risk for certain mental health problems, using special tasks that involve seeing light and images.
BoharsAges 15–25 - NCT05074732Recruiting
Study of forensic mental health admissions after a service move
This study looks at all adult admissions to Ireland’s National Forensic Mental Health Service during a specific time window. It may help improve how the new forensic service at Portrane runs in the future.
DublinAges 18 years+ - NCT05127278Recruiting
Testing a tool to spot early signs of new mental health problems
This study tests whether a new screening tool can detect emerging mental health problems at an early stage. It may help people and clinicians identify issues sooner, so support can happen earlier.
GlasgowAges 12–35 - NCT05185128Recruiting
Social skills training and brain imaging in teens with autism
This study looks at how social thinking and social skills training affect the brain in teens with autism, compared with teens with other severe mental health conditions and typically developing teens. It may help researchers understand what drives social difficulties and what could improve social functioning.
Loma Linda, CaliforniaAges 12–18 - NCT05282277RecruitingPhase 4
Estradiol to improve brain and reward changes in midlife women
This study tests whether a hormone called estradiol (given as a patch and pill) changes how the brain and body respond to reward in some midlife women with low pleasure and/or psychosis symptoms during menopause transition. It may help researchers understand whether estrogen treatment can improve mood-related “reward” function in this group.
Chapel Hill, North CarolinaAges 45–55 - NCT05316883RecruitingPhase 4
Testing blood markers in people on clozapine for schizophrenia
This study looks at “biomarkers,” or blood measures, in people with schizophrenia who respond to clozapine. It may help researchers understand who benefits from clozapine and why, by linking test results to symptom changes.
Glostrup Municipality, DenmarkAges 18–64 - NCT05340348Recruiting
Study of a patient guide for young people at risk of psychosis
This study tests how a “patient guide” (Patientheque) may help young people who are either having a first psychosis episode or showing early warning signs. It aims to support care decisions and reduce stress by improving understanding and follow-up.
BrestAges 15–30
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Common questions
- Are there clinical trials for psychosis?
- Yes. Clin2 currently lists 145 recruiting psychosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psychosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psychosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.