Clinical trials
Pulpitis clinical trials
Below are recruiting pulpitis clinical trials, each written for real people, not researchers. We’re tracking 46 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07123025Recruiting
Partial pulp treatment for painful tooth decay
This study tests if removing only the top part of the damaged tooth nerve can save a deeply decayed molar. It is for people with moderate to severe toothache that doesn't stop, especially when lying down.
Rohtak, HaryanaAges 15–40 - NCT07452614Recruiting
Predicting pulp treatment success with metabolic markers
This trial tests if a metabolic biomarker can predict how well a vital pulp treatment works for tooth pain caused by deep cavities. It aims to help patients keep their natural teeth instead of needing root canals.
BaghdadAges 16–50 - NCT06844448Recruiting
Factors affecting success of vital pulp therapy
This trial looks at how different risk factors affect the success of vital pulp therapy, a treatment that tries to keep the nerve of your tooth healthy after it's been opened during a dental procedure. If you have a tooth that still responds to cold and can be restored, you may be able to join.
BudapestAges 18 years+ - NCT07138287Recruiting
Growth Factor vs Mineral Trioxide for Kids' Permanent Teeth
This study compares two treatments for children’s permanent back teeth with severe, painful nerve inflammation (irreversible pulpitis). It aims to find which approach works better to save the tooth and relieve pain.
MinyaAges 9–16 - NCT07483788Recruiting
Comparing two materials for infected tooth nerve treatment
This study compares two materials (MTA and Biodentine) used to treat a painful, infected nerve in a back tooth. Instead of a full root canal, the dentist will remove only the top part of the nerve and seal it. The goal is to see which material works better to save your tooth.
Karachi, SindhAges 18–40 - NCT07850258Recruiting
Laser vs standard treatment for severe tooth pain
This study compares two ways to treat a severely inflamed tooth nerve (pulpitis) that causes ongoing pain. One method uses a laser, while the other uses standard tools, to see which is better at relieving pain and saving the tooth.
Kütahya, MerkezAges 12–40 - NCT07825415Recruiting
Understanding pulpitis severity to improve tooth-saving treatment
This study looks at whether markers of inflammation in the dental pulp (the nerve and blood vessels inside the tooth) can predict how well a tooth-saving procedure called full pulpotomy works for molars with very deep cavities. If successful, this could help doctors choose the best treatment for severe tooth pain.
Rohtak, HaryanaAges 18–40 - NCT07748676Recruiting
Comparing two rinsing solutions for deep cavities with tooth pain
This study tests whether rinsing the inside of a painful tooth with a special solution (calcium hypochlorite or sodium hypochlorite) after removing the damaged nerve tissue helps preserve the tooth and reduce pain. It's for people with a deep cavity causing severe toothache, and may help avoid a root canal or tooth loss.
Rohtak, HaryanaAges 18–40 - NCT07672873Recruiting
Steroid injection for tooth nerve pain during root canal
This trial tests whether a single injection of dexamethasone (a steroid) near the nerve of a painful lower molar can improve pain relief during a root canal. It's for people with severe tooth nerve pain who haven't taken pain meds recently.
IstanbulAges 18–65 - NCT07638254Recruiting
Buffered vs. Standard Numbing for Dental Pain in Children
This study tests whether a specially prepared numbing medicine works better than standard numbing to reduce pain and anxiety during a dental procedure for children with a painful infected tooth. The goal is to find the gentlest way to numb the area before treatment.
San Luis Potosí City, San Luis PotosíAges 6–12 - NCT07634900Recruiting
Pain relief methods for children's emergency tooth root treatment
This study compares two different numbing techniques used during emergency root canal treatment in children's back lower teeth. Researchers want to see which method works better at relieving pain during the procedure.
Malatya, MalatyaAges 6–14 - NCT07578662Recruiting
Direct Pulp Capping for Deep Cavities in Back Teeth
This study tests a treatment where dentists cap (seal) an exposed tooth nerve in deep cavities of back teeth to see if it heals properly. This might help save your tooth instead of needing a root canal.
Rohtak, HaryanaAges 15–40 - NCT07375576Recruiting
Comparing partial nerve removal to root canal for severe tooth pain
This study compares two ways to treat severe tooth pain from advanced decay: a partial nerve removal (pulpotomy) versus a full root canal treatment. It aims to find which approach works better for saving the tooth.
Hatay, AntakyaAges 18–45 - NCT07287709Recruiting
Laser vs. standard treatment for painful adult molars
This study tests if using a laser is better than the usual method for treating painful, inflamed teeth that still have a live nerve. The goal is to save the tooth and reduce pain without removing the nerve entirely.
AlexandriaAges 16–50 - NCT07163975Recruiting
Complete Pulpotomy vs Root Canal for Diabetic Tooth Infection
This study tests whether a less invasive tooth infection treatment (complete pulpotomy) works as well as a standard root canal for people with type 2 diabetes. It is designed for adults with a specific blood sugar level who have an infected lower back tooth.
Rohtak, HaryanaAges 18–70 - NCT07130760Recruiting
Testing two numbing methods for tooth pain in a back molar
This trial compares two ways to numb a painful lower back molar. If you have a tooth infection that needs a root canal, you may receive one of two injection techniques to see which works better.
Ferrol, A coruñaAges 18 years+ - NCT06904781Recruiting
Pulp treatment for baby teeth with severe toothache
This study compares two ways to treat severe tooth decay in baby molars: removing only the top part of the nerve (pulpotomy) versus removing all of the nerve (pulpectomy). It aims to see which method works better for saving the tooth and relieving pain.
IrbidAges 4–9 - NCT06640231Recruiting
Sealer activation for reducing pain after root canal
This trial tests if activating a sealer inside a tooth after root canal can reduce pain in the days after treatment. It may help people with a painful lower molar that still has a live nerve.
Cairo, New CairoAges 18–40 - NCT06433297Recruiting
Direct vs. indirect pulp capping for deep cavities in lower molars
This study compares two ways to treat deep cavities in lower back teeth when the nerve is exposed. The goal is to see which method better protects the nerve and avoids the need for a root canal.
Rohtak, HaryanaAges 18 years+ - NCT05964933Enrolling by invitation
Pulpotomy vs root canal for painful nerve inflammation
This trial compares two treatments for a tooth nerve that is very inflamed and causing lingering pain: a pulpotomy versus a full root canal. It may help you choose the approach that best relieves symptoms and supports healing for the right kind of tooth.
SingaporeAges 12 years+ - NCT07808684Recruiting
Comparing root canal file designs on debris removal
This study tests two different root canal file designs to see which one removes debris better from the end of the root. It may help people who need a root canal on a tooth with a single root canal.
Minya, Minya GovernorateAges 20–40 - NCT06514053Recruiting
Predicting success of molar pulp treatment
This study looks at whether certain signs in your tooth can help predict if a special type of filling (pulpotomy) will work for deep cavities in back teeth. It may help find the best treatment for you.
Hong KongAges Any age - NCT07759349RecruitingEarly Phase 1
Pain relief choices after root canal treatment
This study compares three different pain relievers to see which works best for pain after a single-visit root canal. It may help find better ways to manage post-procedure discomfort.
Karachi, SindhAges 18–60 - NCT07696702Recruiting
Comparing pulp capping for deep cavities in adult back teeth
This study tests two ways to treat deep cavities that reach the nerve of the tooth, to see which helps the nerve heal better. It may be an option if you have a deep cavity in a lower molar and the nerve is still healthy.
Rohtak, HaryanaAges 18–40
Hear when a new Pulpitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pulpitis?
- Yes. Clin2 currently lists 46 recruiting pulpitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulpitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulpitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.