Clinical trials
Pulpitis clinical trials
Below are recruiting pulpitis clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05964933Enrolling by invitation
Pulpotomy vs root canal for painful nerve inflammation
This trial compares two treatments for a tooth nerve that is very inflamed and causing lingering pain: a pulpotomy versus a full root canal. It may help you choose the approach that best relieves symptoms and supports healing for the right kind of tooth.
SingaporeAges 12 years+ - NCT07759349RecruitingEarly Phase 1
Pain relief choices after root canal treatment
This study compares three different pain relievers to see which works best for pain after a single-visit root canal. It may help find better ways to manage post-procedure discomfort.
Karachi, SindhAges 18–60 - NCT07696702Recruiting
Comparing pulp capping for deep cavities in adult back teeth
This study tests two ways to treat deep cavities that reach the nerve of the tooth, to see which helps the nerve heal better. It may be an option if you have a deep cavity in a lower molar and the nerve is still healthy.
Rohtak, HaryanaAges 18–40 - NCT07532200Recruiting
Pain genes and inflammation in tooth root canal treatment
This research study examines how your genes affect pain and inflammation when you have a painful tooth that needs root canal treatment. By studying these responses, researchers hope to better understand why some people experience different levels of pain during dental procedures.
New Delhi, National Capital Territory of DelhiAges 18–50 - NCT07166679Recruiting
Larger root canal tip for healing infection in back molars
This study tests whether making the tip of the root canal slightly larger during a single root canal treatment helps the infection heal better and reduces pain afterward. It is for people with a dead lower back molar that has an infection around the root tip.
RohtakAges 18–65 - NCT07517367RecruitingPhase 4
Cooling before numbing for tooth nerve pain
This study tests whether applying cold to your gum before a numbing injection helps the anesthetic work better for a severely painful lower front tooth. Researchers want to see if this simple cooling step reduces pain during the procedure.
Samsun, AtakumAges 18–60 - NCT07409896Recruiting
Comparing two numbing shots for painful lower first molars
This study compares two numbing methods for severe tooth pain (pulpitis) in a lower first molar. If you have a tooth that needs a root canal and the pain lingers after cold, this trial may help determine which anesthetic works better for you.
Rawalpindi, Punjab ProvinceAges 18–55 - NCT06514053Recruiting
Predicting success of molar pulp treatment
This study looks at whether certain signs in your tooth can help predict if a special type of filling (pulpotomy) will work for deep cavities in back teeth. It may help find the best treatment for you.
Hong KongAges Any age - NCT05816525Recruiting
Study tooth symptoms and cavity depth after partial removal
This study looks at how tooth symptoms and the depth of a cavity affect outcomes when dentists remove only part of the decayed tissue. You might benefit by getting care guided by careful tooth testing and dental imaging, while contributing to better treatment decisions for deep cavities.
EspooAges 18–50 - NCT06918639Recruiting
Pulpotomy for painful adult teeth with deep cavities
This study tests a treatment called pulpotomy for adults with a deep cavity in a tooth that is causing pain. If you have a tooth that hurts but is still healthy enough to save, this treatment might help relieve the pain and keep the tooth.
Alcorcón, MadridAges 18 years+ - NCT07410780Recruiting
Pain after root canal with two different sealers
This trial compares two types of root canal filling materials—bioceramic and calcium hydroxide—to see which one causes less pain after the procedure. If you have a tooth with a live but inflamed nerve, you may be able to join.
Rawalpindi, Punjab ProvinceAges 18–40 - NCT06613932Recruiting
Saving a painful molar with protein gel and minerals
This study tests whether a special protein-rich gel (L-PRF) combined with a tooth-repairing mineral (nanohydroxyapatite) can help save a painful back molar tooth by treating the nerve inside, instead of removing it. The goal is to see if this treatment stops pain and keeps the tooth healthy.
Cairo, New CairoAges 15–30 - NCT05812053Recruiting
Testing eggshell powder for pulpotomy in baby molars
This trial tests whether applying eggshell powder during a baby tooth pulpotomy (a procedure to treat the nerve tissue) can help heal deep cavities. It may be considered for children whose affected baby molars can be restored and show no signs of infection or bone damage.
Tanta, Gharbia GovernorateAges 4–7 - NCT05860712Recruiting
Cinnamon vs chlorine rinse after baby tooth nerve treatment
This trial tests whether a cinnamon extract rinse works as well as a chlorine-based rinse to reduce pain and fight infection after pulpectomy (removing the nerve tissue) in baby teeth. It may help you understand which rinse causes less post-treatment discomfort.
CairoAges 4–8 - NCT06843525Recruiting
Bite force measurements for molar dental work
This trial measures how your bite force changes after getting a filling or root canal on a lower back tooth. It helps doctors understand if different dental treatments affect your ability to chew.
Newark, New JerseyAges 18–89 - NCT06854744Recruiting
Olive oil and zinc oxide for baby tooth root canals
This study tests a mixture of olive oil and zinc oxide to treat infected baby molars. It aims to see if this natural treatment works as well as standard medicine for stopping infection and saving the tooth.
Tanta, Gharbia GovernorateAges 4–7 - NCT06975761RecruitingPhase 2
Comparing two root canal fillings for pain
This study compares two types of root canal filling materials to see which one is better at reducing pain after the procedure. If you have a painful lower back tooth that needs a root canal and you are a healthy man aged 20-40, you may be able to join.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT07018284Recruiting
Pain after root canal filling with different sealers
This study compares pain levels after root canal treatment using two different types of sealer material. It aims to find which sealer may cause less discomfort.
MadridAges 18 years+ - NCT07019298Recruiting
Comparing dental filling methods for root canals
This trial studies different ways to fill a root canal after treatment to see which works best. It may help if you have a tooth with an infected or dying nerve.
Madrid, SpainAges 18 years+ - NCT07101068Recruiting
Comparing two ways to give dental numbing for kids
This study tests a new dental injector against a traditional syringe to see which one causes less pain and anxiety for children getting numbed for their first cavity treatment.
Cairo, Cairo GovernorateAges 6–8 - NCT07242742Recruiting
Pulpotomy vs. root canal for deep cavities
This trial compares two treatments for very deep cavities that reach the tooth's nerve. It tests whether a less invasive partial nerve removal (pulpotomy) works as well as a full root canal. It may help you keep your tooth without needing a full root canal.
SingaporeAges 12 years+ - NCT07250399Recruiting
Pain after root canal treatment with different tools
This trial compares two different ways of cleaning a tooth's root canal to see which causes less pain during and after treatment. It is for people with severe tooth pain in an upper premolar.
CairoAges 20–50 - NCT07297836Recruiting
Dentist practices for treating baby teeth in France
This study surveys dentists in France about how they treat non-vital (nerve-damaged) baby teeth. It aims to understand current professional practices.
StrasbourgAges 18 years+ - NCT07306533Recruiting
Menstrual phase and dental pain relief study
This trial tests whether the phase of your menstrual cycle affects how well local anesthesia works for a root canal. It may help dentists give you better pain control based on your cycle.
New Delhi, Delhi(दिल्ली)Ages 18–45
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Common questions
- Are there clinical trials for pulpitis?
- Yes. Clin2 currently lists 50 recruiting pulpitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulpitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulpitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.