Clinical trials · Columbus, OH
Rectal Cancer clinical trials in Columbus
We’re tracking 8 recruiting rectal cancer studies with a site in or near Columbus — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Columbus
- NCT07407647RecruitingPhase 2
Vaginal DHEA for better vaginal health after pelvic radiation
This study tests whether a vaginal insert of DHEA (a hormone) can help with vaginal health problems caused by pelvic radiation for anal, rectal, or gynecologic cancers. It is for women who are already postmenopausal and are about to start radiation.
Columbus, OhioAges 50 years+ - NCT06205485RecruitingPhase 3
Chemotherapy and surgery vs chemoradiation for rectal cancer
This trial compares two approaches for early-stage rectal cancer: chemotherapy plus local surgery versus standard chemoradiotherapy. It aims to see if less intensive treatment can work just as well, reducing side effects.
Columbus, OhioAges 18 years+ - NCT06746012Recruiting
Health app study for colorectal cancer survivors and their caregivers
This study tests a mobile health program to help colorectal cancer survivors and their family caregivers stick to healthy lifestyle habits. It's for survivors who are at least 6 months past treatment and have a smartphone.
Columbus, OhioAges 18 years+ - NCT06682793RecruitingPhase 1/Phase 2
Study of A2B395 therapy for solid tumors with EGFR and HLA loss
This trial tests a new cell therapy called A2B395 for cancers that have EGFR, a protein on the cell surface, and have lost a specific marker called HLA-A*02. The therapy uses specially engineered immune cells to target and kill these cancer cells. This may help patients with colorectal, lung, head and neck, breast, kidney, or other solid tumors that are no longer responding to standard treatments.
Columbus, OhioAges 18 years+ - NCT06051695RecruitingPhase 1/Phase 2
CAR T cell therapy for mesothelin-positive solid tumors
This trial tests a new type of immune cell therapy (CAR T-cells) designed to target cancer cells that have a protein called mesothelin but have lost a marker that lets them hide from the immune system. It's for people with advanced solid tumors who have already tried standard treatments.
Columbus, OhioAges 18 years+ - NCT06459869RecruitingPhase 1
NG-350A plus chemoradiotherapy for advanced rectal cancer
This trial is testing a new virus-based therapy (NG-350A) combined with standard chemoradiotherapy for people with locally advanced rectal cancer. It aims to see if the combination is safe and can help shrink tumors before surgery.
Columbus, OhioAges 18 years+ - NCT07429110Recruiting
ColoSeal device study for rectal cancer surgery patients
This study tests a device called ColoSeal that protects the connection made during rectal cancer surgery. It is for patients who are having surgery to remove the tumor and reattach the bowel, and who also need a temporary ostomy.
Columbus, OhioAges 22–75 - NCT06424522Recruiting
Enema program for bowel problems after rectal cancer surgery
This trial tests a special enema program to help people with ongoing bowel problems (called LARS) after rectal cancer surgery. If standard treatments haven't worked, this program might offer a new way to manage symptoms like urgency and leakage.
Columbus, OhioAges 18 years+
Hear when a new Rectal Cancer trial opens near Columbus, OH
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Rectal Cancer trials in other cities
Where these studies are running near Columbus
Institutions with a site for the recruiting rectal cancer studies listed above.
- The Ohio State University Wexner Medical Center · 7 studies
- Ohio State Medical University Center
What taking part in a rectal cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting rectal cancer studies in Ohio.
Common questions
- Are there rectal cancer clinical trials near Columbus?
- Yes. We're currently tracking 8 recruiting rectal cancer studies with a site near Columbus, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a rectal cancer study near Columbus?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Columbus to take part?
- Not necessarily. These studies have a site near Columbus, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a rectal cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New rectal cancer studies open near Columbus regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.