Chemotherapy and surgery vs chemoradiation for rectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial compares two approaches for early-stage rectal cancer: chemotherapy plus local surgery versus standard chemoradiotherapy. It aims to see if less intensive treatment can work just as well, reducing side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of rectal cancer that is well or moderately differentiated and mismatch repair proficient.
- Your tumor is at an early stage (cT1-cT2 or cT3ab) and has not spread to lymph nodes or other organs.
- Your tumor is located in the mid to low rectum and can be removed by transanal excision.
- You are healthy enough to undergo major surgery and have normal organ function.
- You have not had prior radiation to the pelvis or treatment for rectal cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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