Clinical trials
Recurrent or Metastatic Solid Tumors clinical trials
Below are recruiting recurrent or metastatic solid tumors clinical trials, each written for real people, not researchers. We’re tracking 3,355 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07056205Enrolling by invitation
Comparing hormone markers in first and returning breast cancer
This trial looks at how certain proteins (ER, PR, and HER2/neu) on breast cancer cells change when the cancer comes back in the same spot. Knowing this could help doctors choose the best treatment for your recurrence.
SohagAges Any age - NCT07016737Enrolling by invitationPhase 3
Chemotherapy and radiation for returning esophageal cancer
This trial tests if adding radiation before and after standard chemotherapy can help people whose esophageal cancer has come back after initial treatment. It aims to improve control of the cancer while keeping side effects manageable.
Nanjing, JiangsuAges 18 years+ - NCT06987084Enrolling by invitationEarly Phase 1
Bryophyllum Tea for Kidney Stone Prevention
This study tests whether a special tea made from the Bryophyllum pinnatum plant can help people who get calcium kidney stones. If you've had a stone or high calcium in your urine, this trial may offer a natural option to try.
Montreal, QuebecAges 18–70 - NCT06982196Enrolling by invitationPhase 3
Sulodexide to prevent psoriasis return after stopping biologic
This trial tests if sulodexide, a medication that helps blood flow, can keep psoriasis from coming back after you have stopped using a biologic drug (such as strychnicolizumab) because your skin was completely clear for 6 months.
Xi'anAges 18–65 - NCT06902792Enrolling by invitationPhase 1
Adebrelimab and trametinib for children with hard-to-treat LCH
This trial tests a combination of two drugs for children and teens with Langerhans cell histiocytosis (LCH) that has not responded to standard treatments or has come back after treatment. The goal is to see if the drugs can shrink lesions and improve symptoms.
Wenzhou, ZhejiangAges Up to 18 years - NCT06896110Enrolling by invitationPhase 1
Spinal chemo and immunotherapy for recurrent high-grade glioma
This trial tests a combination of two drugs—azacitidine and nivolumab—given directly into the spinal fluid for people whose high-grade glioma has come back after initial treatment. The goal is to see if this approach can safely target the tumor and slow its growth.
Iowa City, IowaAges 13 years+ - NCT06883136Enrolling by invitation
Sintilimab plus chemo for elderly advanced lung cancer
This trial tests a combination of the immunotherapy drug sintilimab plus standard chemotherapy (platinum-based doublet) as the first treatment for older adults (60–80) with advanced non-small cell lung cancer that does not have certain gene mutations. The goal is to see if this approach works better than chemotherapy alone.
Jinan, ShandongAges 60–80 - NCT06861114Recruiting
Urine test to detect liver cancer return after surgery
This study tests if a simple urine test can help find early signs of liver cancer coming back after surgery. Patients with early-stage liver cancer who have surgery may join to help improve follow-up care.
Guangzhou, GuangdongAges 18–75 - NCT06847386Enrolling by invitation
Uterine surgery for women with repeated IVF failure
This trial tests whether a surgical procedure to reshape the uterus can improve the chances of a successful embryo transfer in women who have had at least two failed IVF attempts.
Shanghai, Shanghai MunicipalityAges 20–40 - NCT06763965Enrolling by invitationPhase 1/Phase 2
BioTTT001 for recurrent high-grade glioma
This trial tests a new drug called BioTTT001 for people whose high-grade brain tumor has come back after standard treatment. The drug is given through a small device placed in the head to deliver it directly to the tumor area.
Beijing, Chaoyang DistrictAges 18 years+ - NCT06748014Enrolling by invitationEarly Phase 1
Study of aescin plus MPFF for bleeding hemorrhoids
This study tests whether a combination of two medicines (aescin and MPFF) can stop bleeding from mild internal hemorrhoids (grade 1 or 2) and prevent it from coming back. If you have had active bleeding within the past 7 days, this trial may help you find an effective non-surgical treatment.
Chiang Mai, MaungAges 20 years+ - NCT06636669Enrolling by invitationPhase 4
Probiotics to prevent repeat joint infection after replacement surgery
This trial tests whether taking probiotics can help prevent another infection in people who have had a hip or knee replacement that became infected. If you are scheduled for revision surgery due to an infection, this study may be a good fit.
Boston, MassachusettsAges 18–90 - NCT06616727Enrolling by invitationPhase 1
CAR-T cell therapy for recurrent glioblastoma
This trial tests a new CAR-T cell treatment (SNC-109) for people with glioblastoma that has come back after initial treatment. The therapy uses your own immune cells, modified in a lab, to try to attack the tumor.
BeijingAges 18 years+ - NCT06443996Enrolling by invitation
Sleep, mood, and colorectal cancer recovery study
This study looks at how your sleep quality and emotional well-being before surgery might affect your recovery from colorectal cancer. By filling out questionnaires, you help doctors learn whether these factors play a role in the cancer coming back.
ShanghaiAges 18–80 - NCT06398366Enrolling by invitation
Heart tests to prevent another stroke
This study looks at how heart problems might cause strokes. If you had a stroke that doctors can't explain after many tests, this trial will do extra heart monitoring to find possible causes and help prevent another stroke.
Camden, New JerseyAges 18 years+ - NCT06293924Enrolling by invitation
Testing fluid around the heart in recurring pericarditis
This study analyzes pericardial fluid (the fluid around your heart) to understand why pericarditis comes back. If you have pericarditis or other heart fluid buildup requiring drainage, or if you're having heart surgery, you may be able to participate.
Milan, LombardyAges 18 years+ - NCT06090994RecruitingPhase 4
Huaier vs capecitabine to prevent colon cancer return
This study compares two medicines to prevent colorectal cancer from coming back after surgery: a traditional Chinese medicine called Huaier and a standard chemotherapy pill called capecitabine. It is for people with stage 2 colon cancer that was completely removed.
Harbin, HeilongjiangAges 18 years+ - NCT05690191Enrolling by invitation
Chidamide treatment for returning or hard-to-treat lymphoma
This trial studies chidamide (a prescription medicine) in people with diffuse large B-cell lymphoma that has come back or did not respond to at least one prior treatment. It may help shrink tumors and improve disease control for eligible patients.
Suzhou, JiangsuAges 18 years+ - NCT05569980Enrolling by invitation
Study of rectal prolapse surgery in the Nordic region
This study looks at people who are having surgery for rectal prolapse. The goal is to learn more about outcomes and care for patients after surgery.
Aarhus NAges 18 years+
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Common questions
- Are there clinical trials for recurrent or metastatic solid tumors?
- Yes. Clin2 currently lists 3,355 recruiting recurrent or metastatic solid tumors studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrent or metastatic solid tumors trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrent or metastatic solid tumors trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.