Clinical trials
Safety and Tolerability in Healthy Volunteers clinical trials
Below are recruiting safety and tolerability in healthy volunteers clinical trials, each written for real people, not researchers. We’re tracking 79 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07370155RecruitingPhase 1
Testing a new drug's safety in healthy volunteers
This study tests an investigational drug called Migaldendranib in healthy adults to see if it's safe and how the body handles it. It will help decide if further testing is possible.
Brisbane, QueenslandAges 18–65 - NCT06532942RecruitingPhase 1
Safety study of an inhaled drug in healthy adults
This study tests a new inhaled drug (MKND-201) in healthy volunteers to see if it's safe and how the body processes it. If you are a generally healthy adult between 40 and 65, you might be able to help researchers understand if this medicine is safe for future studies.
San Antonio, TexasAges 40–65 - NCT06752122RecruitingPhase 1
Safety study of RCS-21 in healthy volunteers
This study is testing a new inhaled drug called RCS-21 in healthy volunteers to see if it's safe and how the body handles it. You will be closely monitored and may receive either the drug or a placebo.
HanoverAges 18–64 - NCT06894875Recruiting
Lentil protein's effect on blood pressure and exercise
This trial tests a lentil protein supplement to see if it helps control blood pressure, improve blood vessel function, and boost exercise performance. You may be able to join if you're a healthy, active adult aged 18-45.
Melbourne, VictoriaAges 18–45 - NCT06995482RecruitingPhase 1
Testing safety of KSHN001034 in healthy postmenopausal women
This study tests how safe and tolerable a new drug, KSHN001034, is in healthy women who have gone through menopause. It involves multiple doses to see how your body processes the medicine.
Miami Lakes, FloridaAges 45–60 - NCT07291323RecruitingEarly Phase 1
Safety study of JANX011 in healthy adults
This trial tests a new drug called JANX011 in healthy adults to see if it is safe and well tolerated. It is a first step before testing in patients.
Adelaide, South AustraliaAges 18–65 - NCT07302269RecruitingPhase 1
Safety study of VV261 tablets in healthy Chinese volunteers
This trial tests a new tablet called VV261 in healthy volunteers to see how safe it is and how the body processes it. It is an early study to gather important information before larger trials.
Hefei, AnhuiAges 18–45 - NCT07474545RecruitingPhase 1
Safety study of KL0011034 injection in healthy volunteers
This trial tests a new injection called KL0011034 to see if it is safe and how the body processes it. Healthy volunteers aged 18–45 who meet specific health and lifestyle criteria can join.
Changsha, HunanAges 18–45 - NCT07476586RecruitingPhase 1
Study of GenSci161 safety in healthy adults
This trial tests a new medicine called GenSci161 to see if it is safe and how the body handles it. It is for healthy volunteers aged 18 to 45 who are willing to follow study rules and use birth control.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT07516405RecruitingPhase 1
Psilocybin Safety Study in Older Adults
This research tests whether psilocybin (a psychoactive compound from certain mushrooms) is safe and well-tolerated in healthy people aged 65–85. Researchers want to understand how older adults respond to this substance and whether it could be useful for future treatments.
San Francisco, CaliforniaAges 65–85 - NCT07527221RecruitingPhase 1
Safety study of ZE74-0282 in healthy adults
This is an early-stage safety study testing a new experimental drug called ZE74-0282 in healthy volunteers. Researchers want to learn how safe the drug is and how well people tolerate it before testing it in patients with a disease.
Randwick, New South WalesAges 18–55 - NCT07628608Recruiting
Safety and User Experience of a Daily Gut Health Supplement
This study tests a new daily supplement called BP-CBB to see if it's safe and easy for people to use. The supplement is designed to support gut health, and researchers want to understand how it affects bowel function and how comfortable people are taking it.
CorkAges 18–65 - NCT07057726Enrolling by invitationPhase 1
Safety study of SSS39 injection in healthy Chinese adults
This trial tests a new injection called SSS39 in healthy people to see if it's safe and how the body processes it. You must be between 18 and 45, in good health, and not have certain medical conditions or use specific medications.
BeijingAges 18–45 - NCT06533878Enrolling by invitationPhase 1
Safety of HY209 in healthy volunteers
This study tests the safety and tolerability of a new medication called HY209 in healthy volunteers. It helps researchers understand how the drug affects the body and if it causes any side effects.
Anyang-si, Gyeonggi-doAges 19–45 - NCT05041166Enrolling by invitationPhase 1
MRI scan using a safe imaging molecule in healthy adults
This study uses a labeled nutrient-like molecule ([13C]pyruvate) to create clearer MRI images. It’s for healthy volunteers and helps researchers understand how well this imaging agent works.
New York, New YorkAges 18–80 - NCT07271693RecruitingPhase 1
Safety study of a new medicine in healthy volunteers
This trial tests a new medicine called RO7806881 in healthy volunteers to see if it is safe, what dose is best, and how the body handles it. It is an early study that helps researchers decide if the drug should be tested in people with a disease.
ChristchurchAges 18–50 - NCT07658638RecruitingPhase 1
Safety study of TESP-0401 in healthy volunteers
This study tests a new oral medication, TESP-0401, in healthy volunteers to check its safety, how the body processes it, and any side effects. It is a first-in-human trial, so participants help determine if the drug is safe enough for future studies.
Charlestown, Suite 301, 99 Pacific Highway,NSWAges 18–65 - NCT07283263RecruitingPhase 1
Safety study of new drug BMS-986521 in healthy volunteers
This study tests a new investigational drug (BMS-986521) in healthy volunteers to see how safe it is and how the body processes it. It helps researchers decide if the drug can be tested in future studies.
Anaheim, CaliforniaAges 18–80 - NCT07372703RecruitingPhase 1
Safety study of VV913 capsules in healthy Chinese men
This study tests a new capsule called VV913 in healthy male volunteers to see how safe it is and how the body processes it. It is a first-in-human trial in China to gather basic safety information.
Hefei, AnhuiAges 18–45 - NCT07522970RecruitingPhase 1
Safety and Tolerability Study of LG-0317 in Healthy Adults
This early-stage study tests a new experimental drug called LG-0317 in healthy volunteers to see if it is safe and how the body processes it. If you are healthy and meet the basic requirements, this trial may help advance a new treatment option.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT07637981RecruitingPhase 2
Safety Study of DX243 for Hearing Loss in Noise
This study tests a new medicine (DX243) to see if it is safe and well-tolerated in people with hearing difficulties, especially trouble hearing speech in noisy environments. The goal is to understand how the body processes this medicine and whether it might help improve hearing.
Liège, LiègeAges 18–75 - NCT06482190RecruitingPhase 1
Safety study of an inhaled drug in healthy adults
This trial tests the safety of a new inhaled medicine. You must be a healthy nonsmoker, have normal lung function, and agree to avoid certain medications and foods.
Geelong, VictoriaAges 18–60 - NCT07422207RecruitingPhase 1
Safety study of ME3241 in healthy adults
This trial is testing a new intravenous medicine (ME3241) for safety and how the body handles it. It's for healthy adults, so researchers can see how the drug works before testing it in people with the target condition.
Sydney, New South WalesAges 18–55 - NCT05799274RecruitingPhase 1
Safety study of a new PET imaging drug for cancers
This Phase 1 study tests how safe RAD301 is and how it behaves in the body when given for PET imaging in healthy volunteers and people with certain cancers. It may help doctors learn whether this imaging drug can clearly show cancer areas and be tolerated well.
Princeton, New JerseyAges 18 years+
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Common questions
- Are there clinical trials for safety and tolerability in healthy volunteers?
- Yes. Clin2 currently lists 79 recruiting safety and tolerability in healthy volunteers studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and tolerability in healthy volunteers trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and tolerability in healthy volunteers trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.