Clinical trials
Safety and Tolerability in Healthy Volunteers clinical trials
Below are recruiting safety and tolerability in healthy volunteers clinical trials, each written for real people, not researchers. We’re tracking 82 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05799274RecruitingPhase 1
Safety study of a new PET imaging drug for cancers
This Phase 1 study tests how safe RAD301 is and how it behaves in the body when given for PET imaging in healthy volunteers and people with certain cancers. It may help doctors learn whether this imaging drug can clearly show cancer areas and be tolerated well.
Princeton, New JerseyAges 18 years+ - NCT05361733RecruitingPhase 1
Safety and blood-drug study of XFB19 in healthy adults
This Phase 1 study tests whether XFB19 is safe and tolerable in healthy adults and how the drug moves through the body (what the blood levels look like). You would be in the study to help researchers understand early safety and dosing information.
Knoxville, TennesseeAges 18–55 - NCT07682948RecruitingPhase 1
Drug interaction study of UIC202601 and UIC202602 in healthy volunteers
This trial tests how two experimental drugs, UIC202601 and UIC202602, interact with each other in the body. Healthy volunteers take both drugs to check for side effects and how the body processes them.
Anyang, Manan-guAges 19–54 - NCT07235384RecruitingPhase 1
Zai Lab tests ZL-1503 for moderate to severe eczema
This study tests a new medication called ZL-1503 for people with moderate to severe atopic dermatitis (eczema) that hasn't improved enough with topical treatments. The trial will check if the drug is safe and how well it works.
Woolloongabba, QueenslandAges 18–65 - NCT06736587RecruitingPhase 1
Safety study of DWP212525 in healthy adults
This trial studies a new drug (DWP212525) in healthy volunteers to see how safe it is and how the body processes it. If you are a generally healthy adult, you could help researchers learn about the drug's effects.
SeoulAges 19–55 - NCT07235059RecruitingPhase 1
Testing OJR520 in healthy people and those with chronic kidney disease
This study tests a new drug called OJR520 to see if it's safe and how the body processes it. It first tests healthy volunteers and then people with chronic kidney disease to understand the drug's effects.
Miami, FloridaAges 18–65 - NCT07347678RecruitingPhase 1
Safety study of RN5681 in healthy volunteers
This trial tests a new drug called RN5681 to see if it is safe and how the body processes it. It is for healthy people with certain cholesterol levels and may help people with high cholesterol or heart risk in the future.
Brisbane, QueenslandAges 18–65 - NCT07299955RecruitingPhase 1
Testing a new Herceptin shot in healthy men
This trial tests a new version of the breast cancer drug Herceptin (called Bmab3000) given as a single shot under the skin. It looks at how the drug moves through the body, its safety, and how the immune system responds, in healthy volunteers.
Christchurch, Main Building: 264 Antigua Street,Ages 18–65 - NCT07051629RecruitingPhase 1
Testing a new epilepsy medicine for safety in healthy people and patients
This study tests a new medicine called SIF001 for safety. It first gives the medicine to healthy volunteers, and then to people with epilepsy who have seizures even while on their current medicines. The goal is to find a safe dose.
Tucson, ArizonaAges 18–70 - NCT07549919RecruitingPhase 1
Food Effects on a New Experimental Drug in Healthy Men
This study tests how food affects how the body absorbs and processes a new experimental drug called AJ201. Researchers will give the drug to healthy men with and without food to see if it makes a difference, and they'll check for any side effects.
Los Alamitos, CaliforniaAges 18–55 - NCT07184502RecruitingPhase 1
Testing a new injection for weight loss in healthy and overweight adults
This trial tests an investigational injection called ZT003 to see if it is safe and how the body processes it. It is for healthy volunteers or those who are overweight or obese, to help understand how this treatment might work.
Brisbane, QueenslandAges 18–65 - NCT07736638RecruitingPhase 1
Testing safety and tolerability of ABBV-859 in healthy adults
This trial studies a new drug called ABBV-859 in healthy volunteers to see how safe it is and how the body processes it. It helps doctors decide the right dose for future studies.
Anaheim, CaliforniaAges 18–65 - NCT06267183RecruitingEarly Phase 1
Safety study of a new drug in healthy volunteers
This study tests a new investigational drug called SV001 in healthy volunteers to see if it is safe and how the body handles it. It is a first-in-human trial, meaning this drug has not been tested in people before.
ShanghaiAges 18–45 - NCT07570147RecruitingPhase 1
Safety study of ABBV-1451 infusions and injections in healthy adults
This early-stage trial tests how the body handles a new experimental drug called ABBV-1451, given as either an infusion (IV drip) or injection. Researchers want to make sure it's safe and well-tolerated in healthy volunteers before testing it in people with medical conditions.
Grayslake, IllinoisAges 18–60 - NCT06218784RecruitingPhase 1
Testing a new drug for safety in healthy people and those with nerve pain after shingles
This study tests an experimental drug, iN1011-N17, to see how safe it is and how the body processes it. It involves healthy volunteers and people with postherpetic neuralgia (nerve pain after shingles). This may help find better treatments for this type of chronic pain.
Adelaide, South AustraliaAges 18–75 - NCT07433556RecruitingPhase 1
Testing a new stomach acid drug in healthy adults
This phase 1 trial tests a new medicine called IY-828026 in healthy volunteers to see how safe it is and how the body processes it. It's a first step to find the right dose and check for side effects.
SeoulAges 19–50 - NCT06992661RecruitingPhase 1
Inhaled RJ026 study for interstitial lung disease patients
This trial tests a single inhaled dose of RJ026 in patients with interstitial lung disease (ILD), including idiopathic pulmonary fibrosis (IPF) or connective tissue disease-related ILD (CTD-ILD). It helps see how the drug moves through the body and if it's safe.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT04216342RecruitingPhase 1
Testing a new breathing-drug ingredient in healthy adults
This early study (Phase 1) tests how safe and tolerable Fx-5A is, and how the body processes it, in healthy volunteers. It’s mainly looking to understand side effects and drug levels rather than treating a disease.
Bethesda, MarylandAges 18–99 - NCT06105151RecruitingPhase 1
Safety study of VV119 capsules in healthy Chinese volunteers
This trial tests the safety of a new medication, VV119, in healthy Chinese volunteers. It looks at how the body processes the drug and whether food affects it. Healthy adults who meet the study's requirements can participate.
Beijing, Beijing MunicipalityAges 18–60 - NCT06166056RecruitingPhase 1/Phase 2
Testing an inhaled medicine for bronchiectasis safety
This trial tests an inhaled medication for people with bronchiectasis, a lung condition causing chronic cough and mucus. It first checks safety in healthy volunteers, then studies how the drug works in people with bronchiectasis.
CambridgeAges 18–80 - NCT07594977RecruitingPhase 1
How Your Body Processes a New Digestive Medication
This study tests a new tablet (4-MUST) designed to help with digestive function. Researchers want to understand how your body absorbs and processes this medication, whether food affects how it works, and whether it's safe and well-tolerated.
MoscowAges 18–45 - NCT07709494RecruitingPhase 1
Inhaled Rev-56 for healthy volunteers and people with bronchiectasis
This trial tests an inhaled drug called Rev-56 in healthy adults and in adults with non-cystic fibrosis bronchiectasis who have a chronic lung infection with Pseudomonas aeruginosa. It aims to see if the drug is safe, well-tolerated, and helps reduce the bacteria in the lungs.
Miami, FloridaAges 18–80 - NCT07029932RecruitingPhase 1
Testing the safety of multiple doses of BWC0977 in healthy people
This study tests an experimental antibiotic called BWC0977 to see if it is safe and well-tolerated when given as single and multiple doses. It is for healthy volunteers to understand how the drug behaves in the body before moving to patient trials.
Melbourne, VictoriaAges 18–55 - NCT06859281RecruitingPhase 1
Safety of Grammidin throat spray in healthy adults
This trial tests the safety and how the body processes a new throat spray called Grammidin. Healthy volunteers will use the spray so researchers can see how it works and if there are any side effects.
Saint PetersburgAges 18–45
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Common questions
- Are there clinical trials for safety and tolerability in healthy volunteers?
- Yes. Clin2 currently lists 82 recruiting safety and tolerability in healthy volunteers studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and tolerability in healthy volunteers trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and tolerability in healthy volunteers trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.