Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05276557RecruitingPhase 3
Kids study of a breath test to check H. pylori
This Phase 3 study tests whether a urea breath test (a safe breath test) works well and is safe for children ages 3–17. It may help doctors find and manage an H. pylori infection without using repeated samples.
Doral, FloridaAges 3–17 - NCT06899906Recruiting
Dalbavancin as long-term infection control: a safety study
This study looks back at patients who received the antibiotic dalbavancin as a long-term suppressive therapy for stubborn infections. It aims to see how well it worked and if it was safe.
France, LyonAges Any age - NCT07855354Recruiting
Kidney stone surgery: comparing two access points
This study compares two ways to reach kidney stones during a surgery called percutaneous nephrolithotomy (PCNL). The purpose is to see if one method is safer or works better than the other, which may help reduce complications and improve recovery.
CairoAges 18 years+ - NCT06974123Enrolling by invitationPhase 1/Phase 2
Testing a new oral drug for radiation proctitis
This trial tests an oral drug called Teslanbaicin for people who have pelvic cancer and developed radiation proctitis (inflammation of the rectum from radiation therapy). The goal is to see if it is safe and helps heal the inflammation.
Xinxiang, HenanAges 18 years+ - NCT05164263RecruitingPhase 4
Testing empagliflozin for adults with type 2 diabetes on tablets
This study looks at how well and how safely empagliflozin works in real-world care for adults with type 2 diabetes who are not controlled on current pill treatment. Some participants take it with metformin, and the study helps confirm what to expect in everyday patients.
Kabul, AfghanistanAges 18–65 - NCT06914661Enrolling by invitation
DS8201 for metastatic breast cancer: a real-world study
This trial looks at the safety and effectiveness of DS8201 in people with metastatic breast cancer (cancer that has spread to other parts of the body). Doctors will review medical records to see how well the drug works and how safe it is.
Changchun, JilinAges 18–100 - NCT06244537Recruiting
MR-Linac radiation for advanced colon cancer
This trial tests a new radiation machine called MR-Linac for people with advanced colon cancer that cannot be removed by surgery. The goal is to see if it is safe and works well.
Chengdu, SichuanAges 18 years+ - NCT05349552Recruiting
Radiation for lung or chest cancers in specific locations
This trial studies how safe and effective a type of focused radiation called SBRT is for cancer tumors in certain chest locations. It’s meant for people whose tumor is small (up to 5 cm) and who don’t have widespread, uncontrolled spread.
Beijing, Beijing MunicipalityAges 18–80 - NCT06826885Recruiting
Comparing two types of radiation for breast cancer
This trial is testing how well two different radiation techniques, IMPT and IMRT, work for treating breast cancer. It aims to see which one is safer and more effective, so you might benefit from a potentially better treatment approach.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07362693Recruiting
Biologic drugs for allergic bronchopulmonary aspergillosis with asthma
This study tests if biologic drugs are safe and effective for people with allergic bronchopulmonary aspergillosis (ABPA) who also have severe asthma. It may help if you've had an asthma attack in the past year.
Jinan, ShandongAges 18 years+ - NCT07683377Recruiting
Stent-assisted coil treatment for ruptured brain aneurysms
This trial tests if using a stent with coils to treat a ruptured brain aneurysm is safe and effective. It is for people who have a specific type of aneurysm (wide-necked, cystic) and are treated soon after the rupture.
Xi'an, ShaanxiAges 18–80 - NCT06976229RecruitingPhase 1
Stem cell therapy for recent spinal cord injury
This phase 1 trial tests a new treatment made from stem cells (XS228) for people who had a spinal cord injury 14 to 60 days ago. Doctors want to see if it's safe and if it might help with recovery.
Guangzhou, GuangdongAges 18–65 - NCT05039619RecruitingPhase 2
Obinutuzumab trial for adolescents with active lupus kidney inflammation
This Phase 2 study tests obinutuzumab, a targeted antibody medicine, in teens with active lupus nephritis (inflammation in the kidney). It looks at whether it helps kidney disease and is safe, including how the body handles the drug.
Loma Linda, CaliforniaAges 5–17 - NCT07284459RecruitingPhase 2
Testing PIPE 791 for idiopathic pulmonary fibrosis
This trial tests an investigational drug called PIPE 791 for people with idiopathic pulmonary fibrosis (IPF). It aims to see if the drug slows lung function decline, and you may continue your current IPF medicine.
Mar del Plata, Buenos AiresAges 40 years+ - NCT07453004RecruitingPhase 2
Study of plonmarlimab for frequent gout attacks
This trial tests a new investigational drug called plonmarlimab for people with frequent, painful gout flares who cannot take standard treatments. The goal is to see if it can reduce pain and inflammation from the flare.
Bengbu, AnhuiAges 18 years+ - NCT07681271RecruitingPhase 2
Testing Remibrutinib for papulopustular rosacea
This study tests an experimental drug called remibrutinib (taken as a pill) to see if it can safely reduce the redness and bumps caused by papulopustular rosacea. It is for people with moderate to severe symptoms who have not had success with other treatments.
El Paso, TexasAges 18 years+ - NCT07830719RecruitingPhase 2
Study of a new drug for heart disease and inflammation
This study tests a new medicine called YMI024 for people with stable coronary artery disease (blockages in heart arteries) and higher than normal levels of inflammation. The drug aims to reduce inflammation and may lower the risk of future heart problems.
Fairhope, AlabamaAges 18–80 - NCT06712316RecruitingPhase 2/Phase 3
New drug plus chemotherapy for advanced lung cancer
This trial tests a new investigational drug combined with chemotherapy for people with advanced non-small cell lung cancer that has not been treated before. The goal is to see if it is safe and works better than current treatments.
Birmingham, AlabamaAges 18 years+ - NCT05731258Recruiting
Watch how liposomal doxorubicin is used after breast cancer
This is an observational study that follows people receiving add-on (adjuvant) chemotherapy after primary breast cancer. It aims to understand treatment patterns and outcomes for patients healthy enough to receive liposomal doxorubicin and who have no major complications.
Hangzhou, ZhejiangAges 18–75 - NCT04617756RecruitingPhase 2
Durvalumab plus chemo before surgery for high-risk upper urinary tract cancer
This trial studies whether durvalumab (an immunotherapy) given with chemotherapy before surgery can improve outcomes for people with high-risk cancer in the kidney pelvis or ureter. It is mainly looking at safety and effectiveness in shrinking or controlling the cancer before treatment continues.
Paris, Paris Cx 20Ages 18 years+ - NCT06051045Recruiting
Bulevirtide for chronic hepatitis B and D
This study tests a drug called bulevirtide for people with chronic hepatitis B and D co-infection. It aims to see if the drug is safe and effective, and to study biomarkers that may help predict how well it works.
StockholmAges 18 years+ - NCT07871110RecruitingPhase 2
New pill combined with hormone therapy for advanced prostate cancer
This study tests a new pill (TT00420) taken with standard hormone therapy for prostate cancer that has spread and is no longer responding to initial hormone treatment. The goal is to see if the combination can help slow the cancer's growth and is safe.
Fuzhou, FujianAges 18 years+ - NCT07871838Recruiting
Shorter radiation course for endometrial cancer
This trial tests a shorter course of pelvic radiation for people with endometrial cancer after surgery. It aims to see if it is safe, works well, and improves quality of life.
Montreal, QuebecAges 18 years+ - NCT07856329RecruitingPhase 2/Phase 3
Gene therapy for duchenne muscular dystrophy
This trial tests a gene therapy to help boys with Duchenne muscular dystrophy (DMD) keep their muscle strength. It aims to see if the treatment is safe and effective for young boys who are still walking.
BrusselsAges 6–10
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.