Clinical trials
Saliva clinical trials
Below are recruiting saliva clinical trials, each written for real people, not researchers. We’re tracking 82 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07122128Recruiting
Saliva test for early oral cancer in people with OSMF
This trial studies whether a simple saliva test can help detect oral cancer early in people who have a condition called oral submucous fibrosis (OSMF), which raises the risk of oral cancer. Healthy volunteers and those with OSMF or proven oral cancer are needed.
Jāmshoro, SinchAges Any age - NCT05791149Recruiting
Saliva test to help diagnose oral cavity cancer
This study looks for changes in saliva (epigenetic biomarkers) that may help doctors diagnose squamous cell carcinoma in the mouth. You may be asked for saliva samples and usual clinical checks to see whether the test can help with diagnosis, especially before surgery.
Amiens, PicardieAges 18 years+ - NCT06444776Recruiting
Taste and saliva changes during radiotherapy for head & neck cancer
This study looks at how radiation therapy for head and neck cancer changes your sense of taste and saliva. It aims to better understand and manage these side effects.
Aarau, Canton of AargauAges 18 years+ - NCT07631624Recruiting
Blood test for lung cancer screening in smokers and former smokers
This study tests whether a simple blood test that detects smoking-related changes in DNA can help identify who should get lung cancer screening. Researchers want to see if this test is better at finding people at risk than current methods.
Antwerp, AntwerpenAges 50 years+ - NCT06561971Recruiting
How spinning speed affects saliva tests in smokers
This trial looks at how different speeds of spinning saliva samples affect a marker of inflammation (hs-CRP). It compares people who don't smoke, light smokers, and heavy smokers to see if the spinning speed matters for test results.
Izmir, ÇiğliAges 18–30 - NCT06869135Recruiting
Saliva testing for brain diseases
This trial is collecting saliva samples from people with Alzheimer's, Parkinson's, or other brain diseases to find new ways to diagnose them. It may help improve early detection.
Florence, FIAges 45 years+ - NCT03233256Enrolling by invitation
Breath and saliva tests in healthy adults
This study measures substances in your breath and saliva to understand what can be detected from the body. You might help by providing samples, as long as you’re generally healthy and meet the study’s age and health requirements.
Aurora, ColoradoAges 18–45 - NCT05724992Recruiting
Study genetic testing in families at pancreatic cancer risk
This program invites people whose families are followed in a pancreatic cancer registry to do a saliva swab genetic test. It helps researchers learn how to identify genetic risk in families and may guide future care.
VeronaAges 18–80 - NCT01789229Recruiting
Tumor and inflammation sample bank for one specific condition
This study builds a secure “tumor sample bank” using tissue collected from people who currently have one diagnosed condition, either cancer (malignant disease) or an ongoing inflammatory condition. Your samples could help researchers study your disease and develop better treatments in the future.
ViennaAges 18 years+ - NCT05895890Recruiting
Studying alcohol-related liver disease and addiction care
This study follows adults with alcohol-related liver disease to better understand and manage alcohol addiction and related health problems. You may be able to help researchers by sharing health information and consented care experiences.
Clamart, Île-de-France RegionAges 18–75 - NCT04442516Recruiting
Testing kidney injury risk from cisplatin cancer treatment
This study looks at how cisplatin chemotherapy affects the kidneys. It may help doctors better predict and protect against kidney damage when patients start cisplatin.
London, OntarioAges 3 months+ - NCT06391671Recruiting
Stress and Weight in Teens: A Personalized Nutrition Study
This study looks at how stress and weight are linked in teenagers. It uses a blood test to find patterns that could lead to personalized nutrition advice. If you join, you'll help researchers understand how your body handles stress and food.
Ghent, Oost-VlaanderenAges 11–17 - NCT07799831Recruiting
Oral health and saliva bacteria in children with juvenile idiopathic arthritis
This study looks at how oral health and mouth bacteria relate to disease activity in children with juvenile idiopathic arthritis (JIA). If your child has JIA, participating could help doctors understand more about the condition and may guide future treatments.
Shanghai, PudongxinquAges 6–16 - NCT07775378Recruiting
Boron and inflammation in gum disease
This study looks at how boron levels, oxidative stress (cell damage), and inflammation (swelling) relate to periodontitis (severe gum disease). It may help understand what causes gum disease and could lead to better treatments.
Istanbul, MaltepeAges 18–65 - NCT06186908Recruiting
Saliva test for gum disease diagnosis
This trial studies certain proteins in your saliva to see if they can help identify different types of gum disease. It may help improve how we diagnose and treat periodontal problems.
Izmir, ÇiğliAges 20–60 - NCT07661784Recruiting
Saliva tests to track gum disease
This study looks at whether substances in your saliva can show if gum disease is getting worse. It might help find a simple way to monitor gum health without needles or X-rays.
IspartaAges 18–65 - NCT06674772Recruiting
Migraine study measuring CGRP levels by age and sex
This study measures a substance called CGRP in saliva from people with migraine and healthy volunteers to see how it changes with age and sex. It may help researchers understand migraine better.
Barcelona, BarcelonaAges 6–75 - NCT06683222Recruiting
How muscle and bone talk to each other in healthy women
This study looks at how signals from muscles affect bone health in women of different ages. It aims to understand why bone density changes over time.
MontpellierAges 20–89 - NCT07599449Recruiting
Tracking respiratory infections in French primary care
This study tracks viruses that cause sudden colds and flu-like illnesses during winter months in France. Researchers collect information from patients seen by participating doctors to better understand which respiratory viruses are circulating and help prepare for future outbreaks.
ParisAges Any age - NCT07593495Recruiting
Electric Nerve Stimulation to Treat Dry Mouth
This study tests whether a gentle electrical nerve stimulation treatment (called TENS) can help increase saliva production in people with dry mouth. Participants will receive this treatment along with standard care and answer questions about how the treatment affects their quality of life.
Toluca, State of MexicoAges 12–90 - NCT06163625Recruiting
Brain activity and memory in treatment-resistant depression
This study looks at how the brain's frontal lobe (DLPFC) works during memory tasks in people with treatment-resistant depression. It compares brain activity between depressed patients and healthy controls using MRI and possibly a brain stimulation technique (rTMS). It aims to understand why some people don't respond to standard treatments.
Toronto, OntarioAges 18–65 - NCT06392997Recruiting
Saliva test for gynecologic conditions before surgery
This study is testing a simple saliva sample to see if it can help detect gynecologic conditions (like endometriosis, fibroids, or ovarian/uterine/cervical cancer) before or during surgery. If you are having surgery or a biopsy for one of these issues, your saliva may help improve diagnosis.
AngersAges 18 years+ - NCT07464483Recruiting
Studying genetics in stem cell and CAR-T therapy patients
This trial analyzes genetic information from patients receiving a stem cell transplant or CAR-T therapy to better understand treatment outcomes. Participation may help researchers improve future therapies.
Bologna, BolognaAges Any age - NCT07421960Recruiting
Periodontitis and sleep quality study
This study looks at how gum disease (periodontitis) might be related to sleep quality. It compares people with healthy gums to those with gum disease.
Istanbul, IstanbulAges 18–65
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Common questions
- Are there clinical trials for saliva?
- Yes. Clin2 currently lists 82 recruiting saliva studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a saliva trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a saliva trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.