Clinical trials
Skin Cancer clinical trials
Below are recruiting skin cancer clinical trials, each written for real people, not researchers. We’re tracking 186 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06956690RecruitingPhase 1/Phase 2
Testing HMBD-501 for HER3-positive advanced solid tumors
This trial tests a new drug, HMBD-501, for people with advanced solid tumors that have a specific protein called HER3. The goal is to see if the drug is safe and if it can help shrink or control the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT06060613RecruitingPhase 1/Phase 2
Engineered immune cells for advanced melanoma or lung cancer
This trial tests a new treatment called OBX-115, which uses a patient's own immune cells that are modified in a lab to better fight cancer. It is for people with advanced melanoma or non-small cell lung cancer that has not responded to standard treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT07362914RecruitingPhase 3
Steroid cream for hand-foot skin reactions from chemo
This trial tests whether a corticosteroid cream can prevent or reduce hand-foot skin reactions caused by liposomal doxorubicin (a type of chemotherapy) in breast cancer patients. If you are starting this chemo and are concerned about skin side effects, this study may offer a way to manage them.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07115043RecruitingPhase 1/Phase 2
Study of AZD6750 for advanced solid tumors
This trial tests a new drug called AZD6750 for people with advanced solid tumors that have not responded to standard treatments. It aims to see if the drug is safe and effective.
Grand Rapids, MichiganAges 18 years+ - NCT06006806Recruiting
Proton therapy skin effects study for breast cancer
This study looks at how proton therapy affects the skin in people being treated for early-stage breast cancer. It aims to understand skin reactions better so doctors can reduce side effects.
Knoxville, TennesseeAges 18 years+ - NCT03210935Recruiting
National registry for rare skin cancer diagnoses
This trial is a French national database that collects information from people with certain rare skin cancers. It may help researchers better understand these cancers and improve future care, using real-world patient data.
Dijon, DijonAges Any age - NCT03093909RecruitingPhase 1
Breathing treatment with gemcitabine for lung cancer spread
This early-stage trial studies an inhaled (aerosol) form of gemcitabine to treat solid tumors that have spread to the lungs. It aims to see whether this lung-focused treatment is safe and how well it might work when standard curative options are not available.
Houston, TexasAges 12–50 - NCT06971848Recruiting
Skin testing for biologic drug allergies
This trial checks if people can safely receive certain biologic drugs without allergic reactions, using skin tests to see how the body reacts. It may help find out if you are allergic to a biologic medicine you have taken before.
AngersAges 18 years+ - NCT04860453Recruiting
Family genetic testing study for patterns of different cancers
This study checks whether gene tests can help understand cancer risk in families where different relatives had different (discordant) cancers. It may help families and doctors better understand whether hereditary cancer risk is possible, even though some parts use routine standard care as a comparison group.
Cleveland, OhioAges 18–100 - NCT06183268Recruiting
Proton therapy for head and neck cancer skin side effects
This study looks at how proton therapy affects skin in people with head and neck cancer. It aims to better understand and manage skin reactions during treatment.
Knoxville, TennesseeAges 18 years+ - NCT06888388Recruiting
Safety of nipple-sparing mastectomy for women with high-risk genes
This study looks at the long-term safety of a type of breast surgery (nipple-sparing mastectomy) in women who carry certain inherited gene changes (BRCA1, BRCA2, PALB2, TP53, CDH1, or PTEN) that increase their risk of breast cancer. The goal is to understand how safe this surgery is over time for these women.
New Haven, ConnecticutAges 18–90 - NCT06444815RecruitingPhase 1
Study of VET3-TGI for advanced solid tumors
This trial tests an experimental treatment called VET3-TGI, which is injected directly into tumors. It is for people with advanced solid tumors who have already tried other treatments and are looking for new options.
Los Angeles, CaliforniaAges 18 years+ - NCT05740033Recruiting
Closing the radial forearm donor site after mouth surgery
This study looks at how best to close the skin area on the forearm after surgeons take tissue to rebuild part of the mouth. If you need a radial forearm tissue reconstruction, you may be asked about outcomes afterward using English questionnaires.
Vancouver, British ColumbiaAges 18 years+ - NCT05786716RecruitingPhase 2/Phase 3
Trastuzumab plus pertuzumab for HER2-mutated cancers
This trial tests whether combining trastuzumab and pertuzumab can treat cancers that have HER2 amplification or an activating HER2 mutation. It looks at people ages 12 and older, and may include both children/teens and adults, using the study drug based on their HER2 test results.
BelfastAges 12 years+ - NCT06606028Recruiting
Blood test for leftover cancer DNA after head and neck cancer treatment
This study uses a simple blood test to look for leftover cancer DNA after treatment for head and neck squamous cell carcinoma. The goal is to see if the test can find very small amounts of cancer early, which might help doctors make better decisions about follow-up care.
San Francisco, CaliforniaAges 18 years+ - NCT07600957Recruiting
Polarized Light Therapy to Ease Radiation Skin Damage
This trial tests whether a special type of light therapy can reduce skin damage and irritation that happens during radiation treatment for breast cancer. If it works, it could help patients feel more comfortable during and after their radiation therapy.
Banī SuwayfAges 35–55 - NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT05269381RecruitingPhase 1/Phase 2
Personalized cancer vaccine with pembrolizumab for advanced solid tumors
This trial tests a personalized vaccine made from your tumor's unique markers, combined with the drug pembrolizumab, to help your immune system fight cancer. It is for people with advanced solid tumors who have already tried standard treatments.
Jacksonville, FloridaAges 16 years+ - NCT05890781Recruiting
Study pediatric cancer using lab-made immune organoids
This trial uses special lab models (“immune organoids”) to study certain cancers in children and young people. It may help researchers learn what those cancers do and improve future treatment ideas.
VillejuifAges Up to 25 years - NCT06673628RecruitingPhase 2
Pembrolizumab plus lenvatinib for skin angiosarcoma
This trial tests a combination of two drugs (pembrolizumab and lenvatinib) for people with a rare skin cancer called cutaneous angiosarcoma that cannot be removed by surgery. The goal is to see if the combination shrinks the tumor or slows its growth.
KashiwaAges 18–85 - NCT05296304RecruitingPhase 1
Bexarotene plus radiation for mycosis fungoides skin lymphoma
This Phase 1 study tests whether the medicine bexarotene combined with radiotherapy can shrink or control mycosis fungoides, a skin lymphoma. It also looks at how safe the combination is and how the body handles the treatment.
Commack, New YorkAges 18 years+ - NCT06847555RecruitingPhase 1/Phase 2
Taurine cream to prevent skin burns from radiation in breast cancer
This trial tests if a taurine cream applied to the skin can prevent or reduce the painful skin reactions caused by radiation therapy for breast cancer. It may offer a simple way to protect your skin during treatment.
Jinan, ShandongAges 18 years+ - NCT06401889Recruiting
Skin care program for breast cancer survivors on hormone therapy
This study tests whether a skin care program can improve the appearance of your skin and your quality of life while you take an aromatase inhibitor (a hormone therapy) after breast cancer treatment. It is designed for women who are starting this type of therapy for the first time.
Jacksonville, FloridaAges 18 years+ - NCT07422974Recruiting
Surgery results after pre-treatment for colorectal cancer
This study looks at how well patients recover from colorectal cancer surgery, comparing those who had chemotherapy or radiation before surgery to those who did not. The goal is to understand if pre-treatment affects surgical outcomes.
OsijekAges 18 years+
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Common questions
- Are there clinical trials for skin cancer?
- Yes. Clin2 currently lists 186 recruiting skin cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a skin cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a skin cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.