Clinical trials
Skin Cancer clinical trials
Below are recruiting skin cancer clinical trials, each written for real people, not researchers. We’re tracking 183 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07142408RecruitingPhase 3
Bacteria reduction before skin cancer surgery on legs
This trial tests if reducing bacteria on your skin before skin cancer surgery on the leg can lower the risk of infection, especially for wounds left open to heal naturally.
Marlton, New JerseyAges 18 years+ - NCT07200544RecruitingPhase 4
Meloxicam for skin cancer surgery pain
This study tests if meloxicam, an anti-inflammatory painkiller, helps control pain after Mohs surgery for skin cancer. It aims to reduce the need for stronger opioid pain medicines.
Oklahoma City, OklahomaAges 18–110 - NCT07257094Recruiting
French questionnaire study for nose reconstruction after skin cancer
This study is testing a new French questionnaire to measure how satisfied people are with their nose reconstruction after skin cancer removal. It will help doctors better understand what matters most to patients after this type of surgery.
CaenAges 18 years+ - NCT07277920Recruiting
Skin lesion study using special microscope and genetics
This study looks at skin spots that might be unusual moles or early melanoma using a special microscope that sees deep into the skin. It aims to match these microscope images with genetic information to better understand these spots.
Modena, MoAges 18 years+ - NCT07288073RecruitingPhase 2
TIL Therapy for Advanced Skin Cancer Patients
This study tests a personalized cell therapy called TIL (tumor-infiltrating lymphocytes) for people with advanced skin cancers that have not responded to immunotherapy. Doctors take your tumor cells, grow immune cells from them, and then infuse them back to fight the cancer.
Boston, MassachusettsAges 18 years+ - NCT07349303RecruitingPhase 2
Pembrolizumab Before Surgery for Stage IIb/c Melanoma
This trial tests whether giving pembrolizumab (Keytruda) before surgery helps people with a certain type of advanced melanoma (stage IIb/c). The goal is to see if this treatment can improve outcomes before the tumor is removed.
GothenburgAges 18 years+ - NCT07422779Recruiting
Immunotherapy for advanced melanoma study
This study tests how well immunotherapy drugs like pembrolizumab and nivolumab work for people with advanced melanoma that has spread. It aims to find markers that predict treatment response.
LjubljanaAges 18 years+ - NCT07448831RecruitingPhase 2
Pembrolizumab before surgery for high-risk melanoma
This trial tests whether giving the immunotherapy drug pembrolizumab before surgery can help people with high-risk melanoma. It is for patients whose melanoma has not spread and who have not had prior treatment for melanoma.
Jette, Brussels CapitalAges 18 years+ - NCT07530887RecruitingPhase 3
Melanoma Re-excision Study: Testing Observation Without Surgery
This study tests whether patients with moderate-thickness skin melanoma need additional surgery after their initial tumor removal, or if careful monitoring alone is enough. The goal is to avoid unnecessary surgery while keeping patients safe.
's-HertogenboschAges Any age - NCT07584291Recruiting
Blood Tests and Tissue Study for Melanoma
This research study analyzes blood and tissue samples from melanoma patients to identify biological markers that could help doctors better understand and treat the disease. Researchers will examine archived tissue samples and blood work to develop improved diagnostic tools.
Xi'an, ShaanxiAges 18–80 - NCT07586891Recruiting
Low-Branched-Chain Amino Acid Diet With Immunotherapy for Stage III Melanoma
This trial tests whether a special diet low in certain amino acids (building blocks of protein), combined with an immune-boosting antibody drug, can safely shrink stage III melanoma that has spread to lymph nodes. The goal is to see if this combination works better than standard treatment.
Xi'anAges 18–75 - NCT07586904RecruitingEarly Phase 1
New Immunotherapy Combination for Advanced Melanoma
This trial tests a combination of two drugs (cadonilimab and interferon) given before surgery to treat advanced melanoma that has spread to nearby lymph nodes or one distant site. The goal is to shrink tumors and improve chances of successful surgery and long-term survival.
Xi'anAges 18–75 - NCT07478900Recruiting
Tattoo marking breast tumors before chemo
This trial tests a simple method: marking the tumor with a small tattoo before chemotherapy. The tattoo helps surgeons find the exact spot for lumpectomy after the tumor shrinks, so you can keep more of your breast.
Bhubaneswar, OdishaAges 18–75 - NCT06823414Recruiting
Robotic-assisted nipple-sparing mastectomy trial
This trial tests a robotic-assisted surgery technique for women who need a mastectomy but can keep their skin and nipple. It aims to improve outcomes for breast cancer patients and those at high risk.
A Coruña, GaliciaAges 18 years+ - NCT07545720RecruitingPhase 2
Pinoxin to prevent radiation skin damage
This study tests whether a protective agent called Pinoxin can prevent or reduce skin damage from radiation therapy. If you're getting radiation treatment for cancer, this trial may help protect your skin during therapy.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05561595Recruiting
Reducing health-related stigma through group support
This trial tests a virtual group program to help people cope with health-related stigma from conditions like obesity, cancer, HIV, diabetes, skin disease, or chronic pain. It aims to reduce internalized stigma and improve well-being.
Gainesville, FloridaAges 18 years+ - NCT06837831Recruiting
Mepilex Lite Dressing for radiation skin damage on anal area
This trial tests a special wound dressing (Mepilex Lite) to treat skin burns from radiation therapy in patients with rectal cancer. It may help heal the skin around the anal canal more comfortably.
Jinan, ShandongAges 18 years+ - NCT07548762Recruiting
Skin-Sparing vs. Standard Mastectomy for Breast Cancer
This study compares two surgical approaches to remove breast cancer: one that preserves more of the skin (skin-sparing) versus a standard approach. The goal is to see which method results in fewer wound-healing problems after surgery.
Guangzhou, GuangdongAges 18–75 - NCT06956690RecruitingPhase 1/Phase 2
Testing HMBD-501 for HER3-positive advanced solid tumors
This trial tests a new drug, HMBD-501, for people with advanced solid tumors that have a specific protein called HER3. The goal is to see if the drug is safe and if it can help shrink or control the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT06060613RecruitingPhase 1/Phase 2
OBX-115 cell therapy for advanced melanoma or lung cancer
This trial tests an experimental cell therapy called OBX-115 for people with advanced melanoma or non-small cell lung cancer that has not responded to standard treatments. The therapy uses your own immune cells to fight the cancer. The study aims to see if it is safe and effective.
Los Angeles, CaliforniaAges 18 years+ - NCT07362914RecruitingPhase 3
Steroid cream for hand-foot skin reactions from chemo
This trial tests whether a corticosteroid cream can prevent or reduce hand-foot skin reactions caused by liposomal doxorubicin (a type of chemotherapy) in breast cancer patients. If you are starting this chemo and are concerned about skin side effects, this study may offer a way to manage them.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07115043RecruitingPhase 1/Phase 2
Study of AZD6750 for advanced solid tumors
This trial tests a new drug called AZD6750 for people with advanced solid tumors that have not responded to standard treatments. It aims to see if the drug is safe and effective.
Grand Rapids, MichiganAges 18 years+ - NCT06006806Recruiting
Proton therapy skin effects study for breast cancer
This study looks at how proton therapy affects the skin in people being treated for early-stage breast cancer. It aims to understand skin reactions better so doctors can reduce side effects.
Knoxville, TennesseeAges 18 years+ - NCT06729814Recruiting
Repeated Breast Radiation Side Effects Study
This study asks whether having radiation therapy again to the same breast or chest (15 sessions over 3 weeks) causes more skin redness, peeling, or pain. The goal is to learn more about side effects so doctors can better prepare and support patients who need a second course of breast radiation.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for skin cancer?
- Yes. Clin2 currently lists 183 recruiting skin cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a skin cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a skin cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.