Clinical trials
Skin clinical trials
Below are recruiting skin clinical trials, each written for real people, not researchers. We’re tracking 645 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06640998Enrolling by invitation
Matrix pro for eyebrow and neck lift
This trial tests a radiofrequency microneedling device called Matrix Pro to lift droopy eyebrows and tighten loose skin under the chin and neck. It may help if you have mild to moderate skin laxity and are willing to avoid other cosmetic treatments during the study.
Marlborough, MassachusettsAges 18–75 - NCT06634472Recruiting
AI scanning to plan reconstructive surgery
This trial uses artificial intelligence to analyze CT scans and help surgeons find the best blood vessels in the leg for reconstructive surgery. It aims to make surgery safer and more precise.
Hong KongAges 18 years+ - NCT06624670RecruitingPhase 3
Testing spesolimab for pyoderma gangrenosum skin ulcers
This trial tests whether the drug spesolimab can help people with a skin condition called pyoderma gangrenosum, which causes painful ulcers. It's for adults who have at least one active ulcer that's at least 2 inches across and needs treatment.
Birmingham, AlabamaAges 18 years+ - NCT06624644RecruitingPhase 2/Phase 3
LNS8801 with or without pembrolizumab for advanced melanoma
This trial tests a new drug called LNS8801, alone or with pembrolizumab, for people with advanced melanoma that has stopped responding to prior treatments, especially anti-PD-1 therapy.
Newport Beach, CaliforniaAges 18 years+ - NCT06615635Recruiting
Radiation device trial for skin cancer in patients with weak immune systems
This trial tests a special radiation device (DaRT) placed directly into skin cancer tumors. It is designed for patients with weakened immune systems (immunocompromised) who have a single skin cancer lesion on the skin (not spread elsewhere).
Gilbert, ArizonaAges 18 years+ - NCT06605404Recruiting
Pan-tumor study of a blood test after cancer surgery
This study is testing a new blood test that looks for leftover cancer cells after surgery. It is for people with different types of solid tumors who are planning to have surgery to cure their cancer. The goal is to see if the test can help guide future treatment decisions.
Birmingham, AlabamaAges 18 years+ - NCT06615453Recruiting
Tixel treatment for dry eye disease and periorbital wrinkles
This study tests a device called Tixel that may help reduce wrinkles around the eyes and improve dry eye symptoms. If you have mild to moderate under-eye wrinkles and dry eyes that bother you a lot, this treatment might be an option.
BirminghamAges 18 years+ - NCT06606028Recruiting
Blood test for leftover cancer DNA after head and neck cancer treatment
This study uses a simple blood test to look for leftover cancer DNA after treatment for head and neck squamous cell carcinoma. The goal is to see if the test can find very small amounts of cancer early, which might help doctors make better decisions about follow-up care.
San Francisco, CaliforniaAges 18 years+ - NCT06596434RecruitingPhase 2
Testing 4-aminopyridine cream for faster burn healing
This study tests a medicine called 4-aminopyridine (also used for nerve conditions) to see if it helps second-degree burns heal faster. If you have a fresh burn, you might be able to join.
Tucson, ArizonaAges 18 years+ - NCT06599411Recruiting
Skin biomarkers for inflammatory disease treatment
This study looks for clues in your skin and blood that could predict how well you'll respond to treatments for conditions like eczema, psoriasis, or lupus. It aims to help doctors choose the best therapy for you.
ParisAges 18 years+ - NCT06451913RecruitingPhase 4
Probiotic for gut health during Lyme disease antibiotics
This trial tests if a probiotic (Saccharomyces boulardii) can help maintain healthy gut bacteria while you take antibiotics for the early skin rash of Lyme disease (erythema migrans). You'll take amoxicillin for 14 days, plus either the probiotic or a placebo.
LjubljanaAges 18 years+ - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT04860453Recruiting
Family genetic testing study for patterns of different cancers
This study checks whether gene tests can help understand cancer risk in families where different relatives had different (discordant) cancers. It may help families and doctors better understand whether hereditary cancer risk is possible, even though some parts use routine standard care as a comparison group.
Cleveland, OhioAges 18–100 - NCT06545682RecruitingPhase 1
Study of alpelisib and pembrolizumab for advanced breast cancer or melanoma
This trial tests a combination of two drugs, alpelisib and pembrolizumab, for people with advanced triple-negative breast cancer or melanoma that has spread. The goal is to see if the combination can help shrink tumors, including those that have spread to the brain.
Houston, TexasAges 18 years+ - NCT06529575Recruiting
How skin color affects pulse oximeter accuracy in children
This study checks if a child's skin color affects how well a pulse oximeter (a small clip on the finger that measures oxygen in the blood) works. It involves children having a heart catheterization, where doctors can directly measure oxygen levels, to see if the pulse oximeter gives the same reading.
New York, New YorkAges 4 weeks–18 years - NCT06529757Recruiting
Skin wetting in burn survivors
This study tests how wetting the skin affects burn survivors and healthy volunteers. It may help find ways to manage body temperature or improve comfort during recovery.
Dallas, TexasAges 18–65 - NCT06527183Recruiting
Fibromyalgia and small fiber nerve study
This study looks at whether people with fibromyalgia or long-term chronic pain have damage to the small nerve fibers in their skin. Understanding this could help develop better treatments.
Boulogne-BillancourtAges 18 years+ - NCT06497712Recruiting
Hypnosis for pain during emergency room stitches
This trial tests if hypnosis can reduce pain when getting stitches in the emergency room. If you have a stitchable wound and are at least 18 years old, you may be able to join.
Clermont-FerrandAges 18 years+ - NCT06489301Recruiting
Laser treatment for skin rejuvenation during tummy tuck
This study tests a laser treatment to see if it can help rejuvenate skin taken during tummy tuck surgery. If you are having a tummy tuck and meet the requirements, you may be able to join.
Fairborn, OhioAges 18 years+ - NCT06474104Recruiting
Blood and skin sample collection for mitochondrial disease
This study collects blood and skin samples from people with primary mitochondrial disease and from healthy volunteers. The samples will help researchers better understand these diseases and develop future treatments.
Ramat Gan, IsraelAges 3–85 - NCT06444815RecruitingPhase 1
Study of VET3-TGI for advanced solid tumors
This trial tests an experimental treatment called VET3-TGI, which is injected directly into tumors. It is for people with advanced solid tumors who have already tried other treatments and are looking for new options.
Los Angeles, CaliforniaAges 18 years+ - NCT06447480RecruitingPhase 3
Comparing isotretinoin to standard care for moderate acne in darker skin
This trial compares oral isotretinoin (a strong acne medication) to standard treatments for people with moderate acne and darker skin tones. It aims to find which treatment works best for skin of color.
Nice, Alpes-MaritimesAges 13–30 - NCT06428721Recruiting
Can laser treatment prevent skin spots in older adults?
This study tests if a laser treatment on your forearms can prevent precancerous spots (actinic keratoses) from developing in older adults with fair skin. You would receive the laser on one arm and a sham treatment on the other, and your skin will be monitored.
Fairborn, OhioAges 60 years+ - NCT06423573Recruiting
Skin cancer risk in epidermolysis bullosa patients using Filsuvez
This study tracks anyone with dystrophic or junctional epidermolysis bullosa who is using Filsuvez gel to see how often skin cancers appear. It is designed to understand the long-term safety of the treatment.
Palo Alto, CaliforniaAges Any age
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Common questions
- Are there clinical trials for skin?
- Yes. Clin2 currently lists 645 recruiting skin studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a skin trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a skin trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.