Clinical trials
Sleepiness clinical trials
Below are recruiting sleepiness clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06711159Recruiting
Searching for a biomarker of sleepiness in severe sleep apnea
This study looks for a biological marker of severe daytime sleepiness in people with severe obstructive sleep apnea who haven't started breathing machine treatment yet. It may help doctors better understand and treat sleepiness in the future.
Koege, Regional ZealandAges 18 years+ - NCT07484217RecruitingPhase 3
Testing solriamfetol for depression with daytime sleepiness
This study tests if the drug solriamfetol can help people with major depression who also feel very tired during the day. It aims to improve both mood and daytime sleepiness.
Tucson, ArizonaAges 18–65 - NCT06484348Recruiting
How food affects sleepiness in narcolepsy and hypersomnia
This study explores how what you eat affects your sleepiness and nighttime sleep quality. Researchers want to learn more about these links in people with narcolepsy type 1 or idiopathic hypersomnia.
Clermont-FerrandAges 18–65 - NCT06698809Recruiting
Treating leftover sleepiness in sleep apnea patients
This study tests if a light therapy device can help reduce daytime sleepiness in people who are already using a CPAP machine for sleep apnea but still feel tired. It involves MRI scans and regular check-ins over two years.
New York, New YorkAges 18–75 - NCT06922487Recruiting
Tiredness study during awake brain tumor surgery
This trial looks at tiredness during awake brain surgery for tumor removal. It might help understand how awake procedures affect patients.
LundAges 18 years+ - NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+ - NCT06568367RecruitingPhase 3
Solriamfetol for shift work disorder (SUSTAIN trial)
This study tests a medication called Solriamfetol (Sunosi) to see if it helps people with shift work disorder stay awake and alert during their shifts. It is a Phase 3 trial, which means it is being studied in a larger group to confirm how well it works and check for side effects.
Auburn, AlabamaAges 18–65 - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT05916287Recruiting
STANISLAS cohort follow-up visit for heart and kidney health
This study is a follow-up visit for people who joined the STANISLAS family health cohort. Researchers look at how genes and environment may affect heart and kidney (kidneys) health over time.
Vandœuvre-lès-Nancy, LorraineAges Any age - NCT05939453Recruiting
Bright light therapy for Prader-Willi sleepiness
This trial studies whether daily bright light therapy can reduce sleepiness in people with Prader-Willi syndrome. It may help by improving daytime alertness, but you must meet specific sleepiness, eye-safety, and mental health criteria to join.
Brooklyn, New YorkAges 6–88 - NCT06306092Recruiting
Sleep for better mental health and school grades
This study looks at how helping teenagers sleep better can improve their mental health and school grades. It is open to students in Swedish high schools and upper secondary schools.
Kristianstad, Skåne CountyAges 13–19 - NCT06371352Recruiting
Brain stimulation for sleep and fatigue in depression
This study tests a noninvasive brain stimulation treatment (theta burst stimulation) to see if it can improve sleep, reduce daytime sleepiness, and ease fatigue in people with depression.
WarsawAges 18–65 - NCT06514482Recruiting
Spanish sleep apnea and daytime sleepiness registry
This study will collect information from people with suspected sleep apnea who feel very sleepy during the day. If you are 18 or older and about to have a sleep study, you may be able to help researchers learn more about this condition.
Logroño, La RiojaAges 18 years+ - NCT07685262Recruiting
Bright light therapy for better daytime function in students
This trial tests if morning bright light therapy can help university students feel more awake and function better during the day. You may be eligible if you live in shared student housing and don't have a diagnosed sleep problem.
Hung HomAges 18 years+ - NCT06861686Recruiting
New classification for obstructive sleep apnea
This study is improving how doctors classify obstructive sleep apnea (a condition where your breathing stops and starts during sleep). It focuses on sleepiness and heart-related risks to help guide treatment. If you are 40 or older and have untreated OSA, you may be able to join.
Antwerp, AntwerpAges 40 years+ - NCT06872593Recruiting
Driving simulator test for sleepiness in sleep apnea
This study tests a new driving simulator test (like a video game) to measure daytime sleepiness, compared to the standard sleepiness test. It looks at people with sleep apnea who temporarily stop using their CPAP machine, to see if the new test is accurate.
Zurich, ZRHAges 18 years+ - NCT07082829RecruitingPhase 1
Study of ORX142 in Healthy Adults Ages 18 to 80
This study tests an experimental drug called ORX142 in healthy volunteers to see how it is processed by the body. It helps doctors understand the drug's safety before testing in patients.
Lincoln, NebraskaAges 18–80 - NCT07311434Recruiting
Sleep quality and morning wellness study
This study tests if a dietary supplement can help people with mild sleep issues sleep better and feel more refreshed in the morning. It's for generally healthy adults who are not taking sleep medications or other supplements.
San Francisco, CaliforniaAges 22–59 - NCT07579871Recruiting
Sleep patterns and recovery after first stroke
This study looks at how sleep affects recovery in people who have had their first ischemic stroke (a stroke caused by a blood clot). Researchers want to understand whether sleep quality influences how well patients regain function after stroke.
Lund, Skåne CountyAges 18 years+ - NCT06336525Enrolling by invitation
Sleep health in rural Appalachia and Mississippi Delta
This study examines how sleep is linked to heart and metabolic health in people living in rural Appalachia and the Mississippi Delta. If you are already part of the RURAL Study, you may be able to join this sleep-focused part of the research.
Boston, MassachusettsAges 25–65
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Common questions
- Are there clinical trials for sleepiness?
- Yes. Clin2 currently lists 20 recruiting sleepiness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sleepiness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sleepiness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.