Clinical trials
Stress Disorder clinical trials
Below are recruiting stress disorder clinical trials, each written for real people, not researchers. We’re tracking 403 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06234969Recruiting
Brain stimulation for PTSD: a learning study
This study tests whether a non-invasive brain stimulation technique called cTBS can help people with PTSD learn to overcome fear. You will have brain scans and receive stimulation to see if it improves how your brain processes fear-related memories.
Philadelphia, PennsylvaniaAges 18–60 - NCT06266364Recruiting
Vagus nerve stimulation for treatment-resistant PTSD
This study tests if stimulating the vagus nerve with an implanted device can help adults with chronic PTSD who haven't gotten better with standard treatments. You would have the device implanted and then follow the study plan for several months.
Austin, TexasAges 22–79 - NCT06296589Recruiting
Guilt Reduction vs. Prolonged Exposure for PTSD in Veterans
This study compares two types of talk therapy for Veterans with PTSD who also struggle with trauma-related guilt. One therapy focuses on reducing guilt, while the other is a standard trauma-focused treatment.
Little Rock, ArkansasAges 18 years+ - NCT06298279Recruiting
Online CBT for public safety personnel in Canada
This study tests an online therapy program (cognitive behavioral therapy, or CBT) designed specifically for public safety personnel. It looks at how the timing of the course and learning from others affects your progress. You can join from anywhere in Canada.
Regina, SaskatchewanAges 18 years+ - NCT06310109Recruiting
PICU Diaries to Support Children and Families
This study tests whether a special diary, kept by families during the PICU stay, helps children and their parents cope better after leaving the hospital. It is for children who needed a breathing machine for more than 48 hours.
RomeAges Up to 19 years - NCT06332209Recruiting
Telehealth vs. in-person therapy for trauma in Puerto Rican youth
This trial compares two ways of giving a type of therapy called Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) to children and teens in Puerto Rico who have been through a traumatic event and have post-traumatic stress symptoms. One group receives therapy in person at a clinic, and the other group receives therapy through video calls (telehealth), to see which works better.
Charleston, South CarolinaAges 7–18 - NCT06348472Recruiting
Biomarkers and PTSD psychotherapy response
This study is looking at whether certain biomarkers in your blood (related to inflammation and the oxytocin system) can predict how well you respond to trauma-focused psychotherapy. It may help find better ways to personalize PTSD treatment.
Hod HaSharonAges 18–80 - NCT06363968Recruiting
Eye tests to predict PTSD treatment response in veterans
This study looks at whether certain eye tests can help predict how well PTSD treatments work. It's for veterans with PTSD who are not taking certain medications and have no serious eye or health conditions.
Seattle, WashingtonAges 21–75 - NCT06386003RecruitingPhase 2
Psilocybin and talk therapy for chronic PTSD
This trial tests whether a medication called psilocybin (the active ingredient in magic mushrooms) can help people with long-term PTSD when combined with a specific type of talk therapy. The goal is to see if this approach reduces PTSD symptoms more than therapy alone.
Toronto, OntarioAges 18–65 - NCT06394284RecruitingPhase 3
MDMA therapy for PTSD in male Israeli veterans
This study tests whether MDMA (the drug in Ecstasy) can help male Israeli veterans with PTSD feel better, especially if their symptoms are related to moral injury. It involves therapy sessions and monitoring to see how the drug affects your brain and emotions.
JerusalemAges Any age - NCT06418178RecruitingPhase 2
Optimizing MDMA therapy dose for PTSD in veterans
This trial tests different doses of MDMA (a drug sometimes called 'ecstasy') combined with therapy to see which dose works best for treating PTSD in veterans. The goal is to find a safer, more effective dose to help reduce PTSD symptoms.
The Bronx, New YorkAges 18 years+ - NCT06419959Recruiting
NightWare watch for better sleep and heart health in veterans with PTSD
This study tests if a special watch (NightWare) can help veterans with PTSD who have nightmares sleep better and improve heart health. The watch vibrates gently during nightmares to reduce them without waking you up.
Aurora, ColoradoAges 22–88 - NCT06429293Recruiting
Talk therapy for PTSD and heart health
This study tests whether cognitive behavioral therapy (a type of talk therapy) can improve heart health in people with PTSD. If you have PTSD and are at risk for or have heart disease, you may be able to join.
Boston, MassachusettsAges 18–65 - NCT06449326Recruiting
Brain imaging and stimulation study for PTSD in veterans
This study uses brain scans and a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to help reduce PTSD symptoms in veterans. You may be eligible if you have ongoing PTSD symptoms and are on stable medication.
Albuquerque, New MexicoAges 18–80 - NCT06469333Recruiting
Can a memory task help reduce trauma symptoms before therapy?
This study tests whether a computer-based working memory task can help reduce symptoms of trauma and stress in people who are waiting to start therapy. If you have ongoing PTSD or severe stress and haven't yet started counseling, this could be a way to get early help from home.
Vandœuvre-lès-NancyAges 18–65 - NCT06477796Recruiting
Improving sleep in veterans with TBI and sleep problems
This study tests a new way to help Veterans with both a traumatic brain injury (TBI) and sleep problems get better rest. If you are a Veteran with sleep trouble and a history of TBI, this program may help improve your sleep without needing extra medication.
Portland, OregonAges 18–89 - NCT06479447Recruiting
Patient-reported PTSD screening study
This trial is testing a simple way to check for PTSD symptoms using patient-reported questionnaires. It aims to help people who haven't been screened recently get the care they need.
Chicago, IllinoisAges 18 years+ - NCT06521398Recruiting
Postpartum Care for Preterm NICU Babies
This study focuses on helping new mothers of preterm babies (born before 34 weeks) who are getting care in the NICU at HUP. It tests a program to support your transition home after giving birth, so you and your baby can thrive.
Philadelphia, PennsylvaniaAges 16 years+ - NCT06535516Recruiting
Supporting youth and families after tough experiences
This study tests a program to help youth ages 10-15 who have faced child maltreatment, like abuse or neglect. It aims to build resilience in both the youth and their family.
Rochester, New YorkAges 10–15 - NCT06544408Recruiting
Brain stimulation for fast relief of PTSD
This study tests a rapid, non-invasive brain stimulation treatment to reduce PTSD symptoms. It aims to offer a faster way to help adults with PTSD feel better.
Tallahassee, FloridaAges 18–65 - NCT06548126Recruiting
Online parenting program for displaced families
This trial tests an online parenting program for caregivers who have experienced forced displacement. It aims to support families with children aged 6 to 12 by teaching positive parenting skills.
Tempe, ArizonaAges 18 years+ - NCT06589505RecruitingPhase 2/Phase 3
Software app for treating PTSD
This trial is testing a software program (like an app) designed to help treat PTSD. It may be an option if your PTSD is related to a past traumatic event and you haven't already tried several trauma-focused therapies.
Yamanashi, HokkaidoAges 18–65 - NCT05732155RecruitingPhase 2
MDMA-assisted therapy for Israeli veterans with PTSD
This study tests whether MDMA (the active ingredient in Ecstasy) given in therapy sessions can help Israeli special forces veterans with PTSD and moral injury. Participants will receive MDMA alongside talk therapy to see if it reduces symptoms.
AfulaAges 18 years+ - NCT06608277RecruitingPhase 2
Ketamine and nerve block for headache or PTSD after brain injury
This study tests if ketamine infusions or a stellate ganglion block (a numbing injection near the neck) can help people with long-term headaches or PTSD after a traumatic brain injury. It compares these treatments alone and together.
Chicago, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for stress disorder?
- Yes. Clin2 currently lists 403 recruiting stress disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stress disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stress disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.