Clinical trials
Subjective Cognitive Decline (SCD) clinical trials
Below are recruiting subjective cognitive decline (scd) clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06758154Recruiting
Electro-acupuncture for subjective cognitive decline
This study tests whether electro-acupuncture can improve thinking and memory in people with subjective cognitive decline (when you notice memory issues but standard tests are still normal). It involves receiving acupuncture and brain scans over a period of time.
Nanjing, JiangsuAges 55–79 - NCT07213700Recruiting
Long-term study on Alzheimer's disease
This study follows people who are either being evaluated for Alzheimer's disease or have already been diagnosed. Researchers want to track their health over many years to better understand the disease and how treatments affect it.
GrazAges Any age - NCT07395609Recruiting
Brain stimulation to boost memory, movement, and mood in older adults
This study tests whether high-frequency electrical stimulation of the brain can help improve thinking, movement, and mood in older adults who may or may not have early signs of memory decline. Participants will get sessions of stimulation and complete thinking and walking tasks.
Gainesville, FloridaAges 65–89 - NCT06632145Recruiting
A health promotion program for older adults with memory changes
This study tests a group program called Cog-Fun Ageing that helps older adults with memory changes stay active and healthy. If you have mild memory issues but can still think clearly, you may be able to join this Hebrew-speaking program.
JerusalemAges 60 years+ - NCT06429215Recruiting
Virtual reality and telemedicine to lower dementia risk
This trial tests whether a program using virtual reality and telemedicine can help lower the risk of memory decline and dementia in people who feel their thinking is slipping but don't have a diagnosed memory problem.
Rome, LazioAges 55–80 - NCT07402161Recruiting
Finding Alzheimer's earliest signature in memory concerns
This study looks for early signs of Alzheimer's in people who feel their memory is slipping but still function normally. You'll help researchers find a pattern—a 'signature'—in the brain that may signal the earliest stages of the disease.
San Donato Milanese, MilanAges 18 years+ - NCT06896825Recruiting
Staying active with social support and stress relief
This study tests whether a program that combines social support and stress management can help older adults who live alone become more physically active. You'll use a smartphone to track your activity and get support from others.
Phoenix, ArizonaAges 60 years+ - NCT06816797Recruiting
Testing a program for older adults worried about memory
This trial tests a program called Cog-Fun Aging to help older adults who notice memory changes and feel concerned. The study looks at whether the program can improve daily function and well-being.
JerusalemAges 60 years+ - NCT06002477RecruitingEarly Phase 1
Attention study in sickle cell disease
This trial tests a medication to see if it can improve attention in people with sickle cell disease. It may help with thinking and focus.
Nashville, TennesseeAges 55 years+ - NCT06622889Enrolling by invitation
Can changing how you see aging help memory?
This study tests whether changing how older adults think about aging can help with memory concerns. If you are 60+ and feel your memory or thinking is declining (but tests are normal), you may be able to join.
Beijing, Beijing MunicipalityAges 60 years+ - NCT07130669RecruitingPhase 1/Phase 2
Memory and thinking study for older adults
This trial tests a program to help maintain or improve memory and thinking skills in older adults. You may join if you are 60-89, speak English, and live at home or in an assisted-living facility.
Palo Alto, CaliforniaAges 60–89 - NCT07731191Recruiting
Digital tools to predict Alzheimer's risk factors
This study uses smartphone tools to track early signs of Alzheimer's by analyzing risk factors. It is for people with mild cognitive issues (MCI) or subjective cognitive decline (SCD) who do not have dementia.
Brescia, BSAges 18 years+ - NCT06403345Recruiting
Green activity program for memory challenges
This study tests a green activity program for people with memory challenges. You and a friend or family member will take part in outdoor activities to see if they help with thinking and well-being.
Bloomington, IndianaAges 45 years+ - NCT03402919Recruiting
Brain and memory study for people with thinking changes
This study looks at memory and thinking changes using questionnaires, memory testing, and brain scans. It may help researchers better understand neurodegeneration and dementia and how these problems show up over time.
Calgary, AlbertaAges 50–90 - NCT03851523Recruiting
Tracking memory changes in people with early Alzheimer’s symptoms
This study follows people over time to better understand how memory and thinking complaints progress in early Alzheimer’s disease (from “subjective cognitive decline” to mild cognitive problems). It may help researchers understand who is likely to decline and how symptoms change, which could support future treatments.
Barcelona, CataloniaAges 45 years+ - NCT05014893Recruiting
Brain testing and rehab study for thinking changes
This study looks at how brain activity relates to thinking problems and whether a cognitive (thinking) assessment and rehab approach can help adults with memory or thinking changes. You may be asked to take thinking tests and complete study activities during rehab.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06335836Recruiting
Social connections and brain health in memory decline
This study looks at how being socially isolated or socially active affects memory and brain health in people who feel their thinking is getting worse. You may join if you notice a slow decline in memory or thinking, but otherwise have normal test results.
Nanjing, China, JiangsuAges 45–85 - NCT06669546Recruiting
Quiet sounds during deep sleep for memory in older adults
This study tests whether playing a soft, silent sound (or no sound) during deep sleep can improve memory, brain activity, and blood markers. It is for older adults (60-85) who have mild memory issues but are otherwise healthy.
BernAges 60–85 - NCT06701630Recruiting
Italian study of daily thinking and memory scales
This study is testing new questionnaires to better understand everyday thinking and memory problems in older adults. It aims to improve how doctors identify and track conditions like mild cognitive impairment and early dementia.
Milan, MichiganAges 60 years+ - NCT06711952Recruiting
German study of a new memory questionnaire
This study tests a new questionnaire designed to help doctors better understand early memory or thinking problems. It takes place at a memory clinic in Munich and is for people who are already coming in for dementia testing.
München, BavariaAges 50 years+ - NCT06793735Recruiting
Virtual reality app for memory and thinking problems
This trial tests a virtual reality app you can use at home to help with early memory or thinking problems. It may be an option if you have mild cognitive impairment or notice your thinking is slowing down.
Messina, ItalyAges 40–80 - NCT06889818Recruiting
Alzheimer's treatment and diagnostics registry study
This study creates a registry for people who are using newly approved Alzheimer's medications. It tracks how these treatments work over time and may help researchers learn more about diagnosing and treating Alzheimer's.
IncheonAges 19 years+ - NCT06993207Recruiting
Home brain monitoring study for cognitive decline
This study uses a special EEG headband to monitor brain activity at home in older adults. It aims to understand cognitive decline, including Alzheimer's and mild memory problems, and compare results with healthy volunteers.
Zaragoza, ZaragozaAges 60 years+ - NCT07212504Recruiting
Brain stimulation to improve memory in older adults with mild memory problems
This study tests a new type of brain stimulation called accelerated neuromodulation, aimed at improving memory and thinking in older adults with mild memory issues. It uses magnetic pulses to gently stimulate a part of the brain linked to memory.
Toronto, OntarioAges 55–85
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Common questions
- Are there clinical trials for subjective cognitive decline (scd)?
- Yes. Clin2 currently lists 37 recruiting subjective cognitive decline (scd) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a subjective cognitive decline (scd) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a subjective cognitive decline (scd) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.