Clinical trials
Surgical clinical trials
Below are recruiting surgical clinical trials, each written for real people, not researchers. We’re tracking 1,180 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06270407RecruitingPhase 4
Tranexamic acid for fewer complications in plastic surgery
This study tests whether applying tranexamic acid directly to the skin during plastic surgery reduces bleeding or other complications compared to a placebo. It may help you heal better after your procedure.
VejleAges 18 years+ - NCT06239272RecruitingPhase 1/Phase 2
Personalized treatment for NRSTS in children and young adults
This trial tests a personalized treatment plan for children and young adults with a type of soft tissue sarcoma (NRSTS). It uses a combination of surgery, targeted radiation, and two drugs (pazopanib and selinexor) to fight cancer while reducing side effects. The study is looking for people who have not been treated before for this sarcoma.
Atlanta, GeorgiaAges Up to 30 years - NCT06240780Enrolling by invitation
Incrediwear recovery study for ACL and MCL surgery
This trial tests whether wearing Incrediwear clothing helps you recover faster after arthroscopic knee surgery for ACL or MCL tears. It is designed for people about to have surgery and who want to improve their healing process.
Oklahoma City, OklahomaAges 18–65 - NCT04268849RecruitingPhase 3
IV vs oral iron after weight-loss surgery
This Phase 3 study compares taking iron through an IV versus by mouth to treat iron-deficiency anemia after Roux-en-Y gastric bypass or sleeve gastrectomy. The goal is to see which method works better and is safer for improving iron levels and blood counts.
Baltimore, MarylandAges 18 years+ - NCT06186401RecruitingPhase 1
Experimental immune cell therapy for a specific type of brain cancer
This trial tests a personalized immune cell treatment for a glioblastoma brain tumor that has a specific marker called EGFRvIII. The cells are made in a lab and given by infusion, and the study aims to see if they can safely target and attack the tumor.
San Francisco, CaliforniaAges 18 years+ - NCT06192771Recruiting
Swallowing and speech therapy after tongue cancer surgery
This trial tests whether starting speech and swallowing therapy early after surgery helps people with tongue cancer recover their ability to eat and talk. It is for patients having part of their tongue removed and rebuilt with a tissue flap.
Toronto, OntarioAges 18 years+ - NCT06182059Recruiting
Pain after knee replacement study
This study looks at long-term pain after total knee replacement surgery. It may help understand why some people have persistent pain and find ways to prevent it.
Monza, Monza BrianzaAges 18–85 - NCT06178497Recruiting
5-Year Check-In After ACL Repair
This study checks on people who had ACL (anterior cruciate ligament) repair surgery 5 years ago to see how well their knee is doing. It looks at a specific type of ACL tear (a 'proximal' tear) and helps doctors understand long-term results.
Lille, Choisir Une RégionAges 18 years+ - NCT06178484Recruiting
Surgery versus rehabilitation for a torn ACL
This study compares two ways to treat a tear of the anterior cruciate ligament (ACL) near the top of the knee. It looks at whether having surgery is better than a non-surgical approach with physical therapy. You may be eligible if your tear is recent and you have no other knee injuries.
Lille, Choisir Une RégionAges 18 years+ - NCT06133374Recruiting
Genetic testing accuracy: needle biopsy vs. surgery
This study compares genetic testing results from a small needle biopsy to those from the surgically removed thyroid tissue. It aims to see if the biopsy alone can accurately predict the cancer's genetics, which could help guide treatment decisions.
Calgary, AlbertaAges 18 years+ - NCT06101979Enrolling by invitation
Fortiva Tissue Matrix for hernia repair study
This study is testing a material called Fortiva Tissue Matrix in hernia repair surgery. Researchers want to see if it works well and is safe.
Great YarmouthAges 18 years+ - NCT06101745RecruitingPhase 2/Phase 3
Trial to see ureters during abdominal or pelvic surgery
This trial tests a dye called Nizaracianine Triflutate that helps surgeons see the ureters (tubes from kidneys to bladder) during surgery. It aims to make surgery safer by reducing the risk of accidentally injuring the ureters.
Los Angeles, CaliforniaAges 18 years+ - NCT06103136Recruiting
Maestro surgery registry for laparoscopic procedures
This trial is a registry that collects information from people having laparoscopic surgery. It helps doctors understand how the Maestro system works in real-world use.
Denver, ColoradoAges 18–100 - NCT06083844RecruitingPhase 2
Keytruda + Avastin + chemo for ovarian cancer with minimal remaining disease
This trial tests a combination of three drugs—pembrolizumab (Keytruda, an immunotherapy), bevacizumab (Avastin, a blood-vessel blocker), and oral cyclophosphamide (a chemotherapy pill)—for women with high-grade ovarian cancer who have only tiny bits of disease left after finishing their initial treatment.
New York, New YorkAges 18 years+ - NCT06096220Enrolling by invitationPhase 4
Study of two treatments for jaw cysts
This trial tests if applying 5-fluorouracil or Carnoy's solution during surgery helps treat odontogenic keratocysts (a type of jaw cyst) and reduce the chance they come back.
BelgradeAges 18–70 - NCT05929768RecruitingPhase 3
Shorter chemo plus immunotherapy without anthracyclines for early TNBC
This Phase 3 trial tests whether a shorter course of chemotherapy plus immunotherapy can work as well as standard treatment for early-stage triple-negative breast cancer. It avoids anthracycline drugs and may help reduce exposure to those medicines if the shorter plan is effective and safe.
Birmingham, AlabamaAges 18 years+ - NCT06075316Recruiting
Tracking recovery after chest surgery using patient check-ins
This study tests a simple way to track your recovery after major chest surgery by checking in with you through a phone call or online survey. You'll help doctors see how you're doing and improve care for future patients.
Chapel Hill, North CarolinaAges 18–99 - NCT06069479Recruiting
Surgery vs. watching: study for kids with trigonocephaly
This study compares two approaches for children with trigonocephaly (a condition where the skull has a triangular shape): surgery or careful monitoring without surgery. The goal is to understand which approach leads to better clinical results, emotional well-being, and lower costs.
RotterdamAges Up to 8 years - NCT06077422Enrolling by invitationPhase 2/Phase 3
Comparing two pain blocks for heart surgery recovery
This trial compares two types of pain blocks (Exparel vs. Marcaine) given during heart surgery to see which one provides better pain relief. If you are scheduled for a heart surgery through a small or full chest incision, you may be able to join.
New Brunswick, New JerseyAges 18 years+ - NCT04219956Recruiting
Low-sugar diet aims to reduce belly-surgery pain
This study tests whether a special diet low in polyamines (a food-related substance) can reduce pain after major abdominal surgery. It compares pain control while you use a patient-controlled morphine pump or take opioid tablets by mouth after surgery.
BrestAges 18 years+ - NCT06038227Recruiting
Robotic vs. VATS surgery for early lung cancer
This study compares two types of minimally invasive surgery—robotic-assisted (da Vinci) and VATS—for people with early-stage non-small cell lung cancer. The goal is to see which approach might work better and help patients recover faster.
CopenhagenAges 18 years+ - NCT05836844Recruiting
Anchorsure device check for prolapse surgery safety and performance
This trial evaluates how well and how safely the Anchorsure transvaginal device works when used to suspend (support) the top part of the vaginal area during surgery for apical pelvic organ prolapse. It may help improve surgical outcomes and identify risks for people like you needing this type of prolapse operation.
La RochelleAges 50 years+ - NCT06039085Recruiting
Electrical sensing for real-time cancer margin check during prostate surgery
This study tests a new device that uses tiny electrical sensors to help surgeons check if all the cancer has been removed during prostate cancer surgery. It could give real-time feedback so the surgeon can remove leftover cancer right away.
Lebanon, New HampshireAges 18 years+ - NCT05992857Recruiting
Omentum wrap to prevent leaks after Whipple surgery
This trial tests if wrapping a flap of abdominal tissue (omentum) around the arteries during Whipple surgery (pancreaticoduodenectomy) can reduce the risk of a serious leak. It may help patients who have a higher fistula risk score (7 or more) during their open surgery.
ClichyAges 18 years+
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Common questions
- Are there clinical trials for surgical?
- Yes. Clin2 currently lists 1,180 recruiting surgical studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a surgical trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a surgical trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.