Clinical trials
Surgical clinical trials
Below are recruiting surgical clinical trials, each written for real people, not researchers. We’re tracking 1,180 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06023641RecruitingPhase 2
Liposomal irinotecan for children with rhabdomyosarcoma
This trial tests a new way to treat rhabdomyosarcoma using a targeted drug (liposomal irinotecan) based on the tumor's genetic makeup and risk group. It aims to improve outcomes for children and young adults with intermediate or high-risk disease.
Palo Alto, CaliforniaAges Up to 22 years - NCT06025747RecruitingPhase 1
Abemaciclib plus radiation for liposarcoma before surgery
This trial tests a combination of the targeted drug abemaciclib and radiation therapy before surgery for people with a specific type of liposarcoma. The goal is to see if this combination can shrink the tumor and help make surgery more effective.
Seattle, WashingtonAges 18 years+ - NCT06009809Recruiting
Blood flow in kidney and gut arteries during heart surgery
This trial measures how blood flow changes in arteries feeding the kidney and gut while patients are on a heart-lung machine during heart surgery. It may help doctors better understand and prevent organ damage after surgery.
RomaAges 18 years+ - NCT06025253Recruiting
Negative pressure dressing after leg amputation
This trial tests a special wound dressing that applies gentle suction to the incision after major leg amputation. It aims to reduce wound complications and help the stump heal better.
Dublin, DublinAges 18 years+ - NCT06016855RecruitingPhase 4
Surgery before radiation therapy for neuroendocrine tumors
This trial tests if removing as much tumor as possible through surgery before a targeted radiation therapy (PRRT) can help people with well-differentiated neuroendocrine tumors that have spread to the liver. The goal is to see if this approach works better than radiation therapy alone.
Nashville, TennesseeAges 18 years+ - NCT06017817Recruiting
Light therapy for implant gum disease
This study tests a special light-activated treatment (antibacterial photodynamic therapy) to fight infection around dental implants. It may be an option for people with moderate to severe implant-related gum disease who are not smokers and do not have diabetes.
StockholmAges 18–85 - NCT04933435Recruiting
Image-guided radiation plus liver procedures for non-surgical liver cancer
This trial studies a combination approach—special, image-guided radiation and liver procedures—for liver cancer patients who cannot have surgery. It may help shrink tumors while protecting liver function by using planned, targeted treatment.
Durham, North CarolinaAges 18 years+ - NCT05987241RecruitingPhase 2/Phase 3
Using a blood test to guide immunotherapy after bladder/kidney cancer surgery
This study tests whether a blood test that detects tumor DNA can help guide the use of immunotherapy (nivolumab with or without relatlimab) after surgery for urothelial cancer. The goal is to see if starting immunotherapy based on the blood test results can prevent the cancer from coming back.
Phoenix, ArizonaAges 18 years+ - NCT05990062Recruiting
Better fitting prosthetic arms for amputees
This study is testing a new way to design prosthetic arms to make them fit better and work more naturally. It may help people who have used a prosthetic arm before and are looking for a more comfortable and functional device.
Pittsburgh, PennsylvaniaAges Any age - NCT06000943Recruiting
Bleeding and clot risk after heart valve procedure
This study looks at patients who had a TAVR procedure (a new valve put in the heart) to understand their risk of bleeding or clots over the next year. It tracks changes in blood thinner medications at 1 month, 90 days, and 1 year to help doctors personalize care.
AalstAges 18 years+ - NCT05964140RecruitingPhase 3
Testing antibiotics after jaw fracture surgery
This trial studies whether giving (or how giving) antibiotics affects outcomes after surgery for a broken lower jaw (mandible). It may help reduce infection risk and antibiotic-related side effects if the right approach is chosen for the right patients.
Blackburn, LancashireAges 18 years+ - NCT05972343Recruiting
Cooling treatment to shrink breast tumors without surgery
This trial tests a cooling-based procedure (called cryoablation) to destroy a breast cancer tumor in people who cannot or do not want surgery. It may help shrink the visible tumor without needing an operating room.
St Louis, MissouriAges 18 years+ - NCT05954858Recruiting
Surgical flap to help treat glioblastoma by bypassing the blood-brain barrier
This trial tests a surgical technique that places a tissue flap near a glioblastoma surgery site to help medicines reach the brain more effectively. You might be considered if you are planning major brain tumor surgery and meet specific health, imaging, and lab requirements.
New York, New YorkAges 18 years+ - NCT05966961Recruiting
Compare two stitches to close surgical wounds
This trial compares two types of dissolvable stitches to close wounds after abdominal (belly) surgery done through open surgery or small incisions. It aims to see which stitch option works better or is safer for healing and recovery.
NaplesAges 18 years+ - NCT05932017Enrolling by invitation
Compare two ways to see during gum surgery
This trial compares two tools surgeons use to see during gum (periodontal) surgery: magnifying loupes versus a videoscope. It may help improve how the procedure is done for people with more severe gum disease.
Dallas, TexasAges 18 years+ - NCT05920382Recruiting
Radiofrequency treatment for long-term knee pain after knee surgery
This trial studies whether a radiofrequency procedure can reduce chronic knee pain after knee replacement surgery. It may help people who still have bothersome pain between 6 months and 5 years after their operation, as long as their pain pattern and medications are stable.
Barcelona, CataloniaAges 18 years+ - NCT05901545RecruitingPhase 1
Test an iodine-labeled drug to map neck lymph nodes
This Phase 1 study tests a labelling of panitumumab with iodine (111In) to see how well it can identify lymph nodes in head and neck cancer before surgery. The goal is to improve lymph node staging (which can help guide treatment), with the main focus on safety and early performance.
Nashville, TennesseeAges 19 years+ - NCT05890677Recruiting
Surgery versus conservative care for chronic breast-related arm swelling
This trial compares microsurgery to standard conservative therapy for long-lasting arm swelling caused by prior breast cancer. It may help people who still have swelling despite months of decongestive treatment by improving quality of life.
New Haven, ConnecticutAges 18 years+ - NCT05879250RecruitingPhase 2
WP1066 plus radiation for newly diagnosed glioblastoma
This trial tests whether the study drug WP1066 combined with radiation can better control newly diagnosed glioblastoma, a fast-growing brain tumor. It also aims to check safety and how well tumors respond by using brain scans.
Chicago, IllinoisAges 18 years+ - NCT05898932Recruiting
Help improve BPH care using patient health questionnaires
This study tests a better way to manage benign prostatic hyperplasia (BPH) by using your answers to regular health questionnaires. It may help your care team make more informed decisions about your symptoms and treatment over time.
Glenview, IllinoisAges 50 years+ - NCT05867927Recruiting
Robotic gynecologic surgery study for eligible adults
This trial studies robotic surgery technology for women who need a gynecologic procedure and are good candidates for the Intuitive Surgical system. It may help doctors improve how these surgeries are done, and it requires you to follow the study steps and consent to participate.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05858411Recruiting
Biologic gum treatments added to non-surgical cleaning
This trial studies whether adding a biologic medicine to standard non-surgical gum (periodontal) treatment can improve deep gum pockets in certain bone defects. It may help people whose gum disease has specific “intrabony” defects, but you must meet several health and medication rules.
TiranaAges 18 years+ - NCT05852158RecruitingPhase 4
Antibiotics to prevent infection after jaw surgery
This trial tests whether giving antibiotics can lower the chance of infection after orthognathic (jaw) surgery. It may help by preventing post-surgery infections, but participation depends on your health history and medication allergies.
Halifax, Nova ScotiaAges 16 years+ - NCT05817175Recruiting
Registry for breast reconstruction using pre-pectoral implants
This trial is a registry that collects information from adults having breast reconstruction after mastectomy. It focuses on reconstruction done with pre-pectoral implants (sometimes with a tissue expander), to help doctors better understand outcomes and care over time.
Buenos AiresAges 18 years+
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Common questions
- Are there clinical trials for surgical?
- Yes. Clin2 currently lists 1,180 recruiting surgical studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a surgical trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a surgical trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.