Clinical trials
Thoracic Diseases clinical trials
Below are recruiting thoracic diseases clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05877300RecruitingPhase 1
Test a new esophagus implant to rebuild a short esophagus segment
This Phase 1 study tests the safety and feasibility of a new esophagus implant for people who need only a short (about 6 cm or less) section of their esophagus rebuilt after serious injury or scarring. If it does not work, you must be willing to have a planned “rescue” surgery later.
Los Angeles, CaliforniaAges 18 years+ - NCT02860364Recruiting
Checking different cooling levels during part of heart surgery
This trial compares two cooling temperatures during an “aortic hemiarch” operation to see which approach is safer and better for brain protection. It may help guide surgeons on the best cooling strategy for some planned heart surgeries.
Boston, MassachusettsAges 18 years+ - NCT07640828Recruiting
Digital Models to Improve Aortic Stent Graft Outcomes
This study uses computer models and artificial intelligence to better understand how aortic stent grafts (TEVAR) work in patients. Researchers will analyze your medical imaging to create a digital copy of your aorta, which may help doctors predict long-term success and improve future patient care.
MilanAges 18 years+ - NCT04080492Recruiting
Quality of life study for heart disease patients
This study asks people with certain heart conditions to complete follow-up questionnaires to better understand how their quality of life changes over time. It may help improve how care plans are made and supported for patients and their families.
Cleveland, OhioAges 18–70 - NCT03209674Recruiting
Registry tracking outcomes after heart and chest surgery
This is a registry that collects information from people who have heart or chest (thoracic) surgery. It may help doctors understand what improves outcomes after surgery, but it usually does not test a new drug.
Neuilly-sur-Seine, Île-de-France RegionAges Any age - NCT06493227Recruiting
Extended use of bleeding control drugs after heart surgery
This trial is for hospitals, not patients. Hospitals that do many open heart surgeries and whose doctors agree to use certain bleeding control drugs (fibrinolysis inhibitors) as per the study protocol can participate.
Saint PetersburgAges 18 years+ - NCT07407933RecruitingPhase 1/Phase 2
YL201 with other cancer drugs for advanced solid tumors
This trial tests a new drug, YL201, combined with other cancer treatments for people with a certain type of advanced lung cancer (extensive-stage small cell lung cancer). It may help shrink tumors or slow their growth.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05931783Recruiting
Compare two ways to use an artery during heart bypass
This study compares two surgical techniques for heart bypass: using the left internal thoracic artery in one specific way versus another. It may help improve how well the bypass works in people who need bypass surgery for multiple blocked heart arteries.
GrazAges 18–80 - NCT06377033Recruiting
Using health records to advance genomic medicine for all
This study uses electronic health records to learn how to improve genomic medicine across a diverse health system. It may help make DNA-based healthcare more accessible and effective for people with certain conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06758700RecruitingPhase 2
Teniposide for advanced small cell lung cancer with c-Myc
This trial tests a chemotherapy drug called teniposide for people with a specific type of advanced small cell lung cancer that has gotten worse after prior treatment. The goal is to see if teniposide helps shrink tumors or slow the cancer's growth.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07158879Recruiting
Skin Reactions from Thoracic Implant Dressing Study
This trial studies skin reactions caused by dressings used on chest implantable ports (small devices under the skin to deliver chemo). It is for adults starting their first chemo, who have a chest port.
ParisAges 18–100 - NCT05587439Recruiting
Study of inherited genetic risk in lung and related cancers
This study looks for inherited (family-passed) genetic changes that may raise the risk of lung cancer and related thoracic cancers. It may help people and families understand their genetic risk by collecting health information and sometimes specimens from patients and relatives.
Boston, MassachusettsAges 18 years+ - NCT04770571Enrolling by invitation
Study of posterior neck and upper-back spine fixation systems
This trial studies specific surgical hardware used to stabilize the back of the neck and upper back during spine surgery. It may help surgeons compare outcomes for people needing fixation for trauma, instability, failed prior fusion, tumors, or certain degenerative conditions.
Orange, CaliforniaAges 18 years+ - NCT06177925RecruitingPhase 2
Immunotherapy plus chemoradiation for limited spread SCLC
This trial tests a combination of an immunotherapy drug (adebrelimab) plus standard chemotherapy and radiation for people with extensive-stage small cell lung cancer that has only spread to a few places. The goal is to see if this approach can help control the cancer better.
GuangzhouAges 18–75 - NCT06988943Recruiting
Finding lung cancer early with CT screening in Guangzhou communities
This study is testing a way to find lung cancer early by offering free CT scans to people in certain communities in Guangzhou. It helps catch cancer before symptoms start.
Guangzhou, GuangdongAges 40–74 - NCT06658730Recruiting
A study to check long-term safety of a Gore thoracic stent graft
This registry study tracks patients who have or will receive a Gore thoracic stent graft to see how well the device performs over time. It helps doctors understand the device's long-term benefits and any possible complications.
Tucson, ArizonaAges 18 years+ - NCT06373497RecruitingEarly Phase 1
Heart artery health after chest radiation using PET scan
This study looks at how radiation therapy to the chest affects the arteries in your heart. It uses a special PET scan (with a safe radioactive tracer) to check for early signs of inflammation or plaque buildup, which can help doctors find ways to protect your heart during cancer treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT05366140Recruiting
Implanet Jazz spine fusion for adults needing thoracolumbar stabilization
This trial looks at using the Implanet Jazz system during spine fusion surgery for adults who need stabilization in the middle-to-lower back. It may help patients by improving how well the fused spine heals and stays in place.
Lexington, KentuckyAges 18–100 - NCT05628948Recruiting
Donate blood for a heart and metabolism research biobank
This study builds a “biobank,” which is a collection of blood and related samples, to support future research on heart and metabolic (sugar/body-fat) conditions. It may help researchers better understand these diseases and improve future prevention and treatments.
Cleveland, OhioAges 18 years+ - NCT07391293Recruiting
Genetic aortic diseases and heart risks observational study
This study looks at people with genetic aortic diseases to understand risk factors for heart complications. By joining, you help researchers learn more about these conditions and how to better manage them.
MilanAges 14–60 - NCT06630702Recruiting
Spinal cord stimulation for freezing gait in advanced Parkinson's
This trial tests if a small device placed near your spine (spinal cord stimulation) can help improve freezing of gait in people with advanced Parkinson's whose medicines aren't enough. It also aims to reduce leg pain if you have it.
Hsinchu, Hsinchu CityAges 40–85 - NCT05309707Recruiting
Branched stents for certain aortic arch problems
This study looks at using special branched stent-grafts to treat problems in the aortic arch (such as aneurysm or certain tears). It focuses on how well this approach works and how patients do over follow-up visits.
MadridAges 18–90 - NCT07323732RecruitingPhase 2
BIO 300 and radiation for lung cancer with lung scarring
This trial tests if adding BIO 300 to chest radiation is safe and helps people who have both non-small cell lung cancer (early stage) and interstitial lung disease (scarring of the lungs). It aims to find better treatment options for this specific group.
Basking Ridge, New JerseyAges 18 years+ - NCT07488026Recruiting
Brain stimulation for mobility in Parkinson's disease
This trial tests if a type of brain stimulation (transcranial magnetic stimulation) applied to different areas of the brain can improve walking and movement in people with Parkinson's disease. The goal is to see which stimulation site works best for reducing freezing of gait and improving daily mobility.
Recife, PernambucoAges 40 years+
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Common questions
- Are there clinical trials for thoracic diseases?
- Yes. Clin2 currently lists 50 recruiting thoracic diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thoracic diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thoracic diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.