Clinical trials
TMJ clinical trials
Below are recruiting tmj clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07536399RecruitingPhase 3
Bone Marrow Treatment for Jaw Joint Pain Relief
This study tests whether injecting your own bone marrow cells into your jaw joint during a minimally invasive procedure can reduce pain and improve jaw function better than arthroscopy alone. It's for people with significant jaw pain that hasn't improved with conservative treatments like NSAIDs, physical therapy, and bite splints.
New York, New YorkAges 18–75 - NCT07600203Recruiting
Low-level laser therapy for chronic jaw pain
This study tests whether a special laser device called the Erchonia EVRL can reduce chronic jaw pain caused by TMJ (temporomandibular joint) disorders. You would receive laser treatment and rate your pain over time to see if the laser helps more than a placebo.
Acton, MassachusettsAges 22–75 - NCT07683650Recruiting
Hyaluronic acid and platelet gel for jaw joint disc pain
This study tests a mixture of hyaluronic acid (a natural lubricant) and platelet-rich fibrin (from your own blood) injected into the jaw joint to see if it helps people with a misaligned jaw disc and pain. It may improve jaw movement and reduce discomfort.
Al MansurahAges 18–45 - NCT07297459Enrolling by invitation
Surgery options for a jaw joint problem
This trial compares two types of surgery to treat a common jaw joint problem where the disc slips out of place. It looks at which procedure works better for reducing pain and improving function.
StockholmAges 18 years+ - NCT05816226RecruitingPhase 3
Topical cream for jaw joint pain
This Phase 3 study tests a skin-applied treatment (a cream or gel) to reduce pain in the jaw joint (TMJ). You may benefit if you have TMJ pain and can safely use the study medication without conflicting treatments.
San Francisco, CaliforniaAges 18 years+ - NCT06721104Recruiting
Balance and jaw health in autism
This study looks at balance, jaw joint function, and social skills in people with autism. It aims to understand how these areas are connected and could help improve care.
KirikkaleAges 4–21 - NCT07018791RecruitingPhase 3
Art-based pain test for jaw joint disorder patients
This trial tests if using art can help measure pain in people with temporomandibular joint disorders (TMD). It may offer a new way to understand and manage your pain without surgery.
Jeddah, Mecca RegionAges 18 years+ - NCT00932594Recruiting
New treatment approach for jaw joint problems
This trial studies a “serial” (step-by-step) treatment plan for temporomandibular disorders (TMJ), which can cause pain, clicking, and trouble opening your mouth. It may help by improving how your jaw joint moves and reducing symptoms.
Guangzhou, GuangdongAges 16–60 - NCT06782165Recruiting
Long-term follow-up of jaw joint surgery
This study follows up on patients who had jaw joint (TMJ) surgery. It looks at how the joint is doing after 6 months to predict long-term results. It may help understand if earlier checkups can guide care.
HuddingeAges 18 years+ - NCT06966557Recruiting
Nerve block for chronic jaw pain
This trial tests a nerve block treatment for people with long-term jaw pain that hasn't improved with other treatments. It aims to see if this injection can help reduce pain.
Haifa, NorthAges 18 years+ - NCT03991728Recruiting
TMJ implant registry for adults with a new jaw joint replacement
This registry is for adults getting an artificial (alloplastic) full replacement of the jaw joint (TMJ). It collects real-world information about your implant and care to help improve future outcomes.
São PauloAges 18 years+ - NCT07511959Enrolling by invitation
Blood-derived treatment for chronic jaw pain
This trial tests whether a treatment made from your own blood (platelet-rich plasma exosomes) can help relieve long-term jaw joint pain and improve function. If you qualify, you would receive injections directly into your jaw area.
WroclawAges 18 years+ - NCT05439330Recruiting
Dental MRI to help diagnose jaw, gum, and tooth problems
This study tests whether a special dental MRI can give useful pictures to diagnose jaw joint problems, tooth-related tissue changes, and gum/inflammation issues, and to help plan some dental implant treatments. If you need imaging for these reasons, the trial may help doctors choose the best next treatment by using clearer, dedicated scans.
AarhusAges 18 years+ - NCT05447338Recruiting
Manual therapy for neck pain with limited neck motion
This trial tests whether hands-on/manual physical therapy helps people with neck pain and reduced neck movement. It may help improve motion and reduce symptoms if your neck pain fits the trial’s type and severity.
CórdobaAges 25–50 - NCT05710952Recruiting
Orthodontic braces study and how they affect jaw joints
This study looks at whether multi-attachment orthodontic treatment (either on the front or back of teeth) changes the temporomandibular joint, which is the jaw joint. The researchers will assess your jaw joint using a tool called Modjaw.
MontpellierAges 18 years+ - NCT06619574Recruiting
Testing the dental compass for jaw joint positioning
This study tests a new tool called a Dental Compass that helps dentists place your jaw joint back in the right position more accurately and quickly. It may help relieve TMJ pain and improve jaw function.
Gainesville, TexasAges 18–90 - NCT06694532RecruitingPhase 1/Phase 2
Arthrocentesis with hyaluronic acid for TMJ disorders
This trial tests two types of hyaluronic acid (high vs low molecular weight) given during a jaw joint procedure (arthrocentesis) to see which better relieves pain and improves jaw function in people with TMJ disorders.
AsyutAges 18–100 - NCT06748651RecruitingPhase 1
Allocetra injection for jaw joint arthritis
This study tests a new injection called Allocetra directly into the jaw joint to treat pain and inflammation in temporomandibular joint osteoarthritis. Eligible participants must have MRI-confirmed inflammation and meet basic health requirements.
Ramat GanAges 18–60 - NCT06782191Recruiting
Arthroscopic treatments for jaw joint disc displacement
This trial tests two types of jaw joint surgery for people with a displaced disc that still moves. It compares a simpler procedure (flushing the joint) with a more involved one (surgical repair) to see which helps more with pain and jaw function.
HuddingeAges 18 years+ - NCT06782178Recruiting
Comparing two jaw joint procedures for limited mouth opening
This study compares two minimally invasive procedures (arthroscopy using a tiny camera vs. arthrocentesis using a needle to flush the joint) to see which works better for people with a displaced jaw disc that limits mouth opening. It might help you if simple treatments haven't worked.
HuddingeAges 18 years+ - NCT07211711Recruiting
Splint therapy for tinnitus linked to jaw joint issues
This trial tests if a custom mouthpiece (occlusal splint) can relieve ringing in the ears (tinnitus) that started along with jaw or face pain (TMD). It aims to see if stabilizing the jaw helps reduce both the noise in your ears and the discomfort.
São Paulo, São PauloAges 18 years+ - NCT07676695Recruiting
Jaw Device and Sound Waves for Class II Malocclusion
This trial tests a special jaw repositioning device (Twin-Block) combined with low-intensity sound waves (LIPUS) to help treat a class II malocclusion (when the lower jaw is set back) in children and teens. It aims to improve jaw alignment and joint outcomes.
CairoAges 10 months–1.2 years - NCT07477873Enrolling by invitation
Emotions and jaw surgery recovery study
This study looks at how patients feel emotionally and physically before and after jaw surgery. It uses special software and questionnaires to track emotions, and checks the jaw joint and muscles after surgery. The goal is to see how these relate to recovery in patients having planned jaw surgery.
Kaunas, KaunoAges 18 years+ - NCT07469345Enrolling by invitation
Teeth Grinding and Pelvic Pain in Young Men
This study looks at how teeth grinding (bruxism) is linked to pelvic pain, erectile function, and anxiety in young adult men. It aims to understand if these issues are connected, which could help develop better treatments.
KonyaAges 18–30
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Common questions
- Are there clinical trials for tmj?
- Yes. Clin2 currently lists 25 recruiting tmj studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tmj trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tmj trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.