Blood-derived treatment for chronic jaw pain
Part of Bones, joints & muscles, Brain & nervous system, Mouth & dental, Pain clinical trials.
This trial tests whether a treatment made from your own blood (platelet-rich plasma exosomes) can help relieve long-term jaw joint pain and improve function. If you qualify, you would receive injections directly into your jaw area.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have had jaw joint or muscle pain or dysfunction for more than 3 months
- Your jaw problem has been diagnosed using standard criteria (DC/TMD)
- You do not have cancer, a severe autoimmune disease, or uncontrolled diabetes
- You are not pregnant, and do not have a bleeding disorder or serious heart condition
- You are not taking blood thinners (anticoagulants) and do not have an active infection or recent antibiotic use
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether injecting your own bone marrow cells into your jaw joint during a minimally invasive procedure can reduce pain and improve jaw function better than arthroscopy alone. It's for people with significant jaw pain that hasn't improved with conservative treatments like NSAIDs, physical therapy, and bite splints.
This study tests a new treatment for a common jaw joint problem called disc displacement. It compares a concentrated growth factor from your own blood to standard care to see which helps more with pain and jaw movement.
This trial tests whether acupuncture can help relieve jaw pain caused by a condition called temporomandibular disorder (TMD). If you've had jaw pain for at least 3 months and are between 18 and 70, you may be able to join.
This study is testing whether a physiotherapy (physical therapy) program can help people who have pain and tenderness in their jaw joint. It might be a good fit if you are a young adult with a recent jaw joint problem on one side.
This study tests whether injecting iPRF (a therapy made from your blood growth factors) into the jaw joint can reduce symptoms from mild to moderate jaw joint degeneration. It’s being compared against standard care for people who currently are not on other jaw-joint treatments.
This study tests whether injections of platelet-rich plasma (a substance made from your own blood) can reduce pain in the jaw muscles. If you have had jaw muscle pain for at least 3 months, this treatment might help.
Hear when a new Temporomandibular Disorders (TMD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.