Clinical trials
TNF clinical trials
Below are recruiting tnf clinical trials, each written for real people, not researchers. We’re tracking 39 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06062875RecruitingPhase 2
Testing a drug for enlarged prostate symptoms
This trial tests whether a drug called adalimumab (a TNF blocker) can improve symptoms of an enlarged prostate. It is for men aged 45-80 with a large prostate and bothersome urinary symptoms who have not used this type of medication before.
Glenview, IllinoisAges 45–80 - NCT06585982Recruiting
Synbiotics for MAFLD: gut health and liver fat study
This trial tests whether taking a synbiotic (a mix of helpful bacteria and fiber) can improve insulin levels and reduce inflammation in people with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD). It may help by changing the balance of bacteria in your gut.
Semarang, SemarangAges 25–55 - NCT06642207Recruiting
Comparing two biologic drugs for ankylosing spondylitis
This study compares two types of biologic drugs (IL-17 inhibitors vs. anti-TNF drugs) in people with ankylosing spondylitis (a form of arthritis affecting the spine) who have already tried standard treatments. The goal is to see which drug works better for controlling symptoms.
SohagAges 16–60 - NCT06653634RecruitingPhase 4
Optimizing treatment for kids with JIA in remission
This trial tests whether children with juvenile idiopathic arthritis (JIA) who have been doing well for over a year can safely reduce their medications. The goal is to find the best way to keep arthritis under control while avoiding unnecessary treatments.
BergenAges 2–17 - NCT06793085Recruiting
Inflammation Proteins in PCOS Study
This study looks at inflammation-related proteins in women with PCOS to understand what causes the condition. If eligible, you’d help researchers learn more about PCOS, which could lead to better treatments.
KrakowAges 18–45 - NCT06838143Recruiting
Ilaris real-world study for periodic fevers and sJIA
This study watches how people with certain periodic fever syndromes or a severe type of childhood arthritis (sJIA) do on the medicine Ilaris during their regular doctor visits. It collects information to see how well the medicine works in everyday care.
SeoulAges 2–100 - NCT06960564Recruiting
Hyaluronic acid injection for knee osteoarthritis
This study tests whether a hyaluronic acid injection (a natural lubricant for joints) can reduce inflammation markers in the knee for people with osteoarthritis. It may be a good option if you have moderate knee pain that hasn't improved with other treatments.
IstanbulAges 45–75 - NCT07166315Recruiting
Comparing new treatments for arthritis of the spine or joints
This study looks at how well different newer medications work for people with axial spondyloarthritis or psoriatic arthritis. It focuses on those just starting treatment with bimekizumab, risankizumab, guselkumab, upadacitinib, or a TNF inhibitor.
Bath, SomersetAges 18 years+ - NCT07170904Recruiting
Diet, inflammation, and zinc in women of childbearing age
This study looks at how diet, inflammation, zinc levels, and body composition relate to each other in women of different ethnic backgrounds living in Jakarta. It aims to understand nutrition and health patterns in this group.
Jakarta Pusat, DKI JakartaAges 19–49 - NCT07545317Recruiting
IL-23 Inhibitors for Active Crohn's Disease
This study follows patients with moderate-to-severe Crohn's disease who are starting a newer type of biologic medication called IL-23 inhibitors (guselkumab or risankizumab). Researchers want to understand how well these drugs work in real-world clinical practice and compare their effectiveness to other treatments.
Guangzhou, GuangdongAges 18–75 - NCT03358693Recruiting
Study of inflammation patterns in chronic skin diseases
This study looks at molecular (body-level) signatures in people with chronic inflammatory skin conditions. You may help researchers understand what drives inflammation, while receiving standard (already approved) systemic treatment through routine care.
KielAges Any age - NCT07554820RecruitingPhase 4
Heart Protection in Rheumatoid Arthritis With New Medications
This study compares two treatment approaches for people with active rheumatoid arthritis who also have heart disease risk factors. It tests whether a newer drug called tofacitinib, combined with cholesterol medication, can better protect the heart than traditional TNF-inhibitor treatments.
Lahore, Punjab ProvinceAges 50–85 - NCT07389772Enrolling by invitation
Immune markers in tooth retreatments for diabetics
This study tests whether different ways of activating the immune system during root canal retreatment affect levels of certain immune markers (TLR9, IL6, IL10, TNF-alfa) in people with type 2 diabetes. If you need a repeat root canal on a front tooth or lower premolar, you may be able to join.
Kirikkale, KırıkkaleAges 18–50 - NCT07380373Enrolling by invitation
Testing markers in body fluids for lung injury in children
This study looks at two substances in saliva and lung fluid—called IL-6 and TNF-α—in children with severe lung failure (ARDS) who are on a breathing machine. Measuring these markers may help doctors better understand the condition and guide treatment.
CairoAges 1–10 - NCT04646187Enrolling by invitationPhase 4
Lowering biologic doses for Crohn’s and ulcerative colitis
This trial tests whether people with Crohn’s disease or ulcerative colitis who are currently well-controlled can safely use less-frequent anti-TNF medicine. It may help reduce treatment intensity while keeping inflammation under control.
GhentAges 12–25
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Common questions
- Are there clinical trials for tnf?
- Yes. Clin2 currently lists 39 recruiting tnf studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tnf trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tnf trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.