Clinical trials
Tobacco Cessation clinical trials
Below are recruiting tobacco cessation clinical trials, each written for real people, not researchers. We’re tracking 87 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04865276Recruiting
Quit tobacco with a phone-based support program
This study tests a phone (mHealth) program designed to help people stop using tobacco. You may be assigned to either the program or a comparison group, based on your location and the study plan.
Londrina, ParanáAges 18 years+ - NCT06438549Recruiting
Community health workers help pregnant smokers quit
This study tests whether adding a community health worker to your prenatal care team can help pregnant women quit smoking. It's for women who are ready to make a quit plan and are getting care at certain hospitals.
Loma Linda, CaliforniaAges 18 years+ - NCT05415371Enrolling by invitation
Smoking help program for pregnant women in Medicaid
This study tests a smoking-cessation program for pregnant people who smoke while using Medicaid. It may help reduce smoking during pregnancy through structured support calls.
Oklahoma City, OklahomaAges 18–105 - NCT05445804RecruitingPhase 1
Oral cannabidiol (CBD) to help you quit tobacco
This Phase 1 study tests whether taking oral CBD can help people quit tobacco. It also checks safety and helps researchers learn how people respond to the treatment while they practice quitting.
Baltimore, MarylandAges 18–65 - NCT06883097Recruiting
Quitting smoking with HIV: A smoking cessation trial
This study tests whether nicotine replacement therapy (like patches or gum) can help people living with HIV quit smoking. You'll be part of a program that supports your quit attempt while you receive care for HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT07129590Recruiting
Trauma-informed care to help pregnant people quit smoking
This study tests whether a trauma-informed care approach can help pregnant people who have experienced trauma to quit smoking. The study involves clinicians and patients working together to improve smoking cessation support.
San Francisco, CaliforniaAges 18 years+ - NCT07148232RecruitingPhase 4
Helping people experiencing homelessness quit smoking
This study tests an extended program to help people who are homeless and smoke at least 5 cigarettes a day quit smoking. It provides nicotine replacement therapy (like patches or gum) and support over time.
San Francisco, CaliforniaAges 18 years+ - NCT05805722Recruiting
Tobacco quit program for cancer patients and recent quitters
This study offers a structured tobacco-cessation program for people with a history of cancer who currently use tobacco or quit recently. It tests approaches to help you stop using tobacco and stay quit while you’re getting care or recovering.
Richmond, VirginiaAges 18 years+ - NCT06501209Enrolling by invitation
Counseling to help you quit tobacco
This study tests if a special counseling method (called 5A-5R) helps people quit tobacco. If you are an adult who uses tobacco daily and wants to quit, you may be able to join.
DhakaAges 18 years+ - NCT06881069Recruiting
Text-based tobacco cessation support for low-income Utahns
This study tests a text-message program to help people who use tobacco quit. It's designed for adults living in low-income areas in Utah who visit certain clinics.
Salt Lake City, UtahAges 18 years+ - NCT06042361Enrolling by invitation
Making smoke-free housing fairer for residents
This study aims to make smoke-free policies more equitable in affordable housing communities. If you live in one of the six selected properties in Massachusetts, Maryland, or New York, you may be able to participate in a survey or a group discussion.
Boston, MassachusettsAges 18 years+ - NCT05627674Enrolling by invitation
Help improve lung cancer screening and quitting support uptake
This study tests a “precision” approach to help people who are newly eligible for lung cancer screening actually get screened and start smoking-cessation treatment. If it works, it could make screening and quitting help easier to access and more engaging.
St Louis, MissouriAges 18 years+ - NCT06127589Recruiting
Quit for Kids: help parents quit smoking and protect children
This study offers a program to help parents who smoke quit for good, while protecting their young children from secondhand smoke. It uses text messaging and support to make quitting easier.
Hong KongAges 18 years+ - NCT06798324RecruitingPhase 4
Brain stimulation plus smoking cessation medication for quitting smoking
This trial tests whether combining brain stimulation (tDCS) with a smoking cessation medication (varenicline) helps people quit smoking. You would attend daily visits for two weeks.
Toronto, OntarioAges 18–85 - NCT05863923Enrolling by invitation
Text message program to help people with HIV quit smoking
This study tests a texting program that sends messages to help people living with HIV who smoke quit smoking. It may help you reduce tobacco use using regular, motivational text messages.
Worcester, MassachusettsAges 18 years+ - NCT05786547RecruitingPhase 3
Varenicline plus support to help quit tobacco in HIV care
This Phase 3 trial tests a quit-smoking program using varenicline (a medicine) plus additional support, for people with HIV who currently use tobacco. It may help you stop smoking or using tobacco and stay quit with safer, guided care.
Aurora, ColoradoAges 18 years+ - NCT07098065Recruiting
Health warnings and counseling to help you quit smoking
This trial tests whether health warnings and counseling can help smokers quit. You'll get support during visits to your local pharmacy.
DhakaAges 18–90 - NCT06851936Recruiting
Help quitting tobacco for cancer survivors and their caregivers
This study tests a program to help people with a history of cancer and their family caregivers quit using tobacco or nicotine products. You may help researchers learn what works best for supporting quitting in this group.
Gainesville, FloridaAges 18 years+ - NCT06451081Recruiting
Helping Hong Kong smokers quit with a text-based program
This study tests a new program that uses text messages to help people who smoke daily to quit. It is designed for Hong Kong residents who can read Chinese and own a smartphone.
Hong KongAges 18 years+ - NCT06609369RecruitingPhase 2
Sleep and smoking relapse study
This study tests whether improving sleep can help people quit smoking and avoid relapse. It uses brain scans, a quitting medication, and counseling.
New Haven, ConnecticutAges 18–65 - NCT07080788Recruiting
Native American Pain Risk Study: Smoking Cessation
This study looks at how quitting smoking affects pain in Native American adults. Eligible participants are daily smokers who own a smartphone and do not have heart problems or chronic pain.
Tulsa, OklahomaAges 18 years+ - NCT07501624Enrolling by invitation
Pharmacist-led tobacco treatment for HIV patients
This study works with pharmacists at six Ryan White HIV clinics to help people with HIV quit smoking or using tobacco. If you have HIV, are 21 or older, and have already met with a pharmacist about tobacco, you may be able to join.
Charleston, South CarolinaAges 21 years+ - NCT07031024Recruiting
Quit smoking help in the hospital
This trial studies a program to help smokers quit, offered to anyone over 18 who smokes at least one cigarette (or equivalent) a day, regardless of their reason for visiting the hospital or other substance use. If you are a current smoker, you can join to get support for quitting.
Nice, Alpes MaritimesAges 18 years+ - NCT07571018Recruiting
Mobile app to help young adults quit tobacco
This study tests a new smartphone app designed to help people aged 18–30 quit tobacco and nicotine products. Researchers want to learn if the app works and how to improve it based on your feedback and daily experiences.
Las Cruces, New MexicoAges 18–30
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Common questions
- Are there clinical trials for tobacco cessation?
- Yes. Clin2 currently lists 87 recruiting tobacco cessation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tobacco cessation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tobacco cessation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.