Clinical trials
Tobacco Cessation clinical trials
Below are recruiting tobacco cessation clinical trials, each written for real people, not researchers. We’re tracking 77 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06930547Recruiting
Smoking cessation education for recovery
This study tests whether education classes can help people who are in recovery from mental health issues quit smoking. It is for people registered with a Community Mental Health Center who smoke daily.
Erzurum, ErzurumAges 18 years+ - NCT07489443Recruiting
Helping pregnant women reduce tobacco and cannabis use
This study is testing a program to help pregnant women and new mothers cut back on or quit using tobacco and cannabis. It’s designed to see if the program is easy to use and helps improve health for both mom and baby.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05415761Recruiting
Mobile phone support to help you quit smoking in clinic
This study tests different texting/app-based ways to help people quit smoking, especially those who may have less access to care. You may be assigned to one approach and get support through your phone.
Gainesville, FloridaAges 21 years+ - NCT07049757Recruiting
Healthy Family Project: Reducing tobacco smoke in Chinese American homes
This study helps Chinese American families reduce tobacco use and secondhand smoke exposure. Smokers, family members, and community health workers are all welcome.
San Francisco, CaliforniaAges 18 years+ - NCT06837220Recruiting
Smoking cessation program for people in community behavioral health
This study tests a smoking cessation program designed for people who receive care at community behavioral health centers in Chicago. If you're a daily smoker interested in quitting, you may be able to join and get support to help you stop.
Chicago, IllinoisAges 18–26 - NCT05515354RecruitingPhase 4
Smoking quit plan matched to your menstrual cycle phase
This Phase 4 study tests a smoking-quit treatment plan timed to your menstrual cycle. It may help you quit smoking and learn how quitting support works for people who menstruate regularly.
Toronto, OntarioAges 18–40 - NCT07553962Recruiting
How couples support each other when quitting smoking
This study looks at how couples who both smoke can help each other quit. Researchers want to understand the ways partners support one another during a smoking cessation attempt, which may help improve quit success rates.
Denver, ColoradoAges 18 years+ - NCT06876831Recruiting
Lung cancer screening for current and recent smokers
This study aims to create a program to help people get screened for lung cancer while they are in the hospital. It is for people who are at higher risk due to their age and smoking history.
New York, New YorkAges 50–80 - NCT06901713Recruiting
Help quitting smoking with CBT and mindfulness
This trial tests a smoking cessation program that combines cognitive behavioral therapy (CBT) and mindfulness audio to help you quit or reduce smoking. You'll receive digital materials to support you.
HangzhouAges 18–65 - NCT05233228RecruitingPhase 2
Phone-based coaching to help you quit smoking in Laos
This study tests a mobile phone program that gives personalized help to support quitting smoking. If you’re eligible, it may help you plan a quit date and stick with quitting using the app.
ChampasakAges 18–65 - NCT06651684Recruiting
Quit smoking help for parents with social needs
This trial tests if health navigators can help parents who smoke and have unmet social needs to quit smoking. If you smoke and face challenges like trouble paying bills or finding childcare, this program may support you.
Montreal, QuebecAges 18 years+ - NCT04604509RecruitingPhase 4
Smoking quit plan using counseling and nicotine-free medicines
This trial tests whether a quit program that combines counseling with medicines (nicotine replacement, varenicline, or bupropion) helps people stop or cut down smoking. It’s also delivered through telehealth, with repeated check-ins to see how well the plan works and whether it’s safe for you.
Houston, TexasAges 18 years+ - NCT07402642Recruiting
Early Education to Lower Heart Attack Risk Factors
This trial tests if personalized education after a heart attack helps patients lower their future risk of heart problems. It focuses on people who had an emergency procedure to open blocked arteries.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT04903028Recruiting
Brain stimulation to help people quit smoking
This study tests whether a type of brain stimulation (rTMS) can help people stop smoking. It targets brain circuits involved in cravings, aiming to support quitting safely.
Charleston, South CarolinaAges 22–70 - NCT07292883RecruitingPhase 2
Accelerated TMS for smoking cessation
This trial tests whether a rapid form of brain stimulation (TMS) can help people stop smoking. It is designed for adults who are ready to quit within the next month.
Penetanguishene, OntarioAges 18 years+ - NCT06832085RecruitingPhase 4
Comparing stop-smoking medications for adult smokers in Ontario
This study compares three different stop-smoking treatments—nicotine patches, cytisine, or varenicline—to see which works best. If you want to quit or cut down in the next six months, this could help you find the right medication.
Ottawa, OntarioAges 18 years+ - NCT06617312RecruitingPhase 2
Cytisinicline and brain response to smoking cues
This study tests how a medicine called cytisinicline (similar to a plant-based stop-smoking aid) affects brain activity when you see or think about smoking. It may help researchers understand how the medicine works, even if you aren't ready to quit right now.
Los Angeles, CaliforniaAges 18–65 - NCT06566703Recruiting
Testing a program to help quit smoking in tribal communities
This study tests a program called ANSOS to help people who smoke and are American Indian quit. You'd take part in Zoom sessions and be in the study for one year to see how well the program works.
Bethlehem, PennsylvaniaAges 18 years+ - NCT05836103Recruiting
Texting on your phone to help you quit smoking
This trial tests whether smartphone texting messages can help young adults stop smoking. If you’re planning to quit soon, the messages may support you during the quitting process.
Baltimore, MarylandAges 18–30 - NCT05814055RecruitingPhase 2
Kava to help quit smoking by easing stress and sleep issues
This Phase 2 study tests whether kava can help people quit smoking, especially by reducing stress and improving sleep during tobacco abstinence. You may be offered kava as part of a quitting support plan and monitored for safety and progress.
Gainesville, FloridaAges 21–75 - NCT05766553Recruiting
Virtual reality mindfulness to reduce cigarette cravings
This trial tests whether guided mindfulness meditation in virtual reality can lower cigarette cravings and help people quit smoking. It may help by reducing urges to smoke during stressful moments.
IteuilAges 18–75 - NCT03912194RecruitingPhase 3
Training to help you quit smoking sooner and feel better
This Phase 3 study tests a quit-training program that teaches how to handle urges and negative feelings when you start cutting back or stopping smoking. You may benefit by improving your chances of quitting and reducing stress during withdrawal.
Birmingham, AlabamaAges 18 years+ - NCT07592793Enrolling by invitation
Community Health Worker Perspectives on New Programs
This study asks community health center workers and partner staff about their experiences implementing a new health program. Your feedback helps researchers understand what works and what challenges exist in delivering care in community settings.
Boston, MassachusettsAges 18 years+ - NCT07491627Enrolling by invitation
Nicotine's effect on gum disease treatment in smokers and non-smokers
This study looks at how smoking and nicotine affect the success of gum disease treatment. It compares results between smokers and non-smokers who have gum disease.
Liège, LiegeAges 18 years+
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Common questions
- Are there clinical trials for tobacco cessation?
- Yes. Clin2 currently lists 77 recruiting tobacco cessation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tobacco cessation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tobacco cessation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.