Clinical trials
Tobacco Use Cessation clinical trials
Below are recruiting tobacco use cessation clinical trials, each written for real people, not researchers. We’re tracking 105 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06395415Recruiting
Mobile health program for young adult e-cigarette users
This study tests a mobile health program to help young adults ages 18–26 who use e-cigarettes regularly to reduce or quit. It uses text messages to support you, and you'll need to be interested in changing your vaping habits.
Chicago, IllinoisAges 18–26 - NCT06678789Recruiting
Testing low vs high nicotine pouches for smokers
This study compares how low and high nicotine pouches affect adult smokers who want to try a tobacco-free option. You'll attend two visits in Charleston to check health markers.
Charleston, South CarolinaAges 21 years+ - NCT06118502Recruiting
Adaptive quit-smoking treatment for early relapse
This trial tests a flexible treatment approach for smokers who want to quit and are at risk of relapsing early. It aims to help you stay smoke-free by adjusting the support you get.
Charleston, South CarolinaAges 21 years+ - NCT05846841Recruiting
Personalized quit-smoking support in primary care
This study tests a personalized tobacco (smoking) treatment plan delivered in primary care to help reduce cravings and smoking. It may help you quit or smoke less using options like nicotine patches/lozenges or varenicline, chosen to fit your needs.
St Louis, MissouriAges 18 years+ - NCT07161050Recruiting
Low nicotine and price effects on illegal cigarette buying
This study looks at how low-nicotine cigarettes and higher cigarette prices affect people's choices to buy illegal or cheaper cigarettes. It may help understand how to reduce smoking.
Roanoke, VirginiaAges 21 years+ - NCT06909500Recruiting
Vaping cessation app for young adults
This trial tests a smartphone app called ACT on Vaping to help young adults quit vaping. It may help you if you are ready to stop using e-cigarettes and want support through a digital tool.
Seattle, WashingtonAges 18–30 - NCT07059377RecruitingPhase 3
Semaglutide to help smokers with diabetes quit
This study tests if the diabetes drug semaglutide can help people with type 2 diabetes stop smoking more easily. Participants will get either semaglutide or a placebo to see if it improves quit rates.
Ottawa, OntarioAges 18 years+ - NCT06598397RecruitingPhase 4
Quit smoking help for people with HIV in NYC
This study is testing different ways to help people with HIV quit smoking. It combines medication, coaching, and text messages to find the most affordable and effective support.
New York, New YorkAges 18 years+ - NCT03495024RecruitingPhase 4
Varenicline for quitting smoking in people with schizophrenia
This trial tests whether varenicline helps people with schizophrenia or schizoaffective disorder stop smoking. It also looks at related nervous-system side effects that can happen with some anti-psychotic medicines.
Philadelphia, PennsylvaniaAges 18–75
Hear when a new Tobacco Use Cessation trial opens
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Common questions
- Are there clinical trials for tobacco use cessation?
- Yes. Clin2 currently lists 105 recruiting tobacco use cessation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tobacco use cessation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tobacco use cessation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.