Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 947 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07744373Recruiting
Breast milk study for infant food tolerance
This study looks at cells and molecules in breast milk that may affect how babies develop tolerance to foods. If you are a mother exclusively breastfeeding and your baby is under 9 months old, you may be able to join.
IstanbulAges birth–9 months - NCT05706129RecruitingPhase 1/Phase 2
Testing targeted imaging and therapy for advanced solid tumors
This early-phase study tests two radioactive medicines that first help doctors see tumors and, in some parts of the study, treat them. It may help people with advanced, hard-to-remove cancers that have a specific tumor marker (CA IX).
MelbourneAges 18 years+ - NCT05202964Recruiting
Study comfort and safety with oral antibiotics for bone joint infection
This trial studies how tolerable (comfortable) and safe oral antibiotic treatment is for infections in bones or joints. It may help confirm whether taking antibiotics by mouth for at least 6 weeks is well tolerated during treatment.
LyonAges 18 years+ - NCT05318534RecruitingPhase 1
Testing a new medicine for Cold Agglutinin Disease
This Phase 1 study checks whether an investigational medicine is safe and tolerable, and how the body processes it. For people with Cold Agglutinin Disease, it also looks at early blood markers of whether the disease responds.
LeedsAges 18 years+ - NCT04762641RecruitingPhase 1
First-dose safety study of ABL503 for advanced cancers
This Phase 1 trial tests the safety and side effects of ABL503 and finds the best dose to study next. It is for people with advanced cancer that is growing despite prior treatment options.
Duarte, CaliforniaAges 18 years+ - NCT04234724Recruiting
Study of how ANGPTL3 gene variants affect body functions
This study looks at how different ANGPTL3 gene versions may change normal body measurements (such as blood and metabolism). It may help researchers understand why these genetic differences affect health, especially related to fats (lipids) in the body.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07297394Recruiting
How the immune system supports early pregnancy
This study looks at how the immune system helps the body accept a pregnancy. It involves blood samples from people who are pregnant or going through IVF/ICSI, or who have had a miscarriage.
BaselAges 18 years+ - NCT03457402Recruiting
Training kids to wait for bigger rewards
This study tests a learning task (with a tablet) to help children practice waiting for a bigger reward instead of acting on impulse right away. It may be useful for young children who show very high impulsivity or hyperactivity.
Sacramento, CaliforniaAges 3–6 - NCT06815107Recruiting
Ureteral double-J stent tolerance study
This study looks at why some people have trouble tolerating a ureteral double-J stent, a small tube placed in the ureter to help urine drain. Researchers will ask about symptoms to find risk factors for poor tolerance, which may help future patients.
AmiensAges 18 years+ - NCT06271343Recruiting
Kidney transplant tolerance study
This trial is testing a way to help your body accept a kidney transplant without needing lifelong anti-rejection drugs. It is for people getting a kidney from a living donor who is a relative and has a compatible blood type.
Nantes, Loire-AtlantiqueAges 18 years+ - NCT06972069RecruitingEarly Phase 1
Building tolerance to a new kidney with Sip-Tego
This study tests a new combination of medicines (Sip-Tego) to help your body accept a living donor kidney without needing lifelong anti-rejection drugs. It is for people with advanced kidney failure who are getting a first or second transplant.
Boston, MassachusettsAges 18–65 - NCT02969798Recruiting
Study of prediabetes with abnormal sugars and medicines
This study looks at adults with prediabetes—specifically abnormal fasting and/or 2-hour blood sugar tests—to see whether a treatment helps improve sugar control. You may also be compared with people who have normal blood sugar (the control group).
San Antonio, TexasAges 18–65 - NCT04199676Recruiting
Testing blood sugar after delivery for gestational diabetes
This study checks your blood sugar shortly after birth (on day 0 or day 1) to see how well glucose testing works for people who had gestational diabetes. The results may help guide follow-up care and reduce the risk of longer-term blood sugar problems.
Long Beach, CaliforniaAges 18 years+ - NCT05398276Recruiting
Coaching for exercise anxiety through body-sensation exposure
This study tests whether a behavioral training approach that helps you become more comfortable with body sensations during exercise can reduce exercise anxiety. It may help people who are less active because they feel anxious when exercising.
East Brunswick, New JerseyAges 40 years+ - NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05575882Recruiting
Skin cream trial to prevent relapses in very dry eczema skin
This trial tests whether a cosmetic cream can reduce eczema flare-ups and is comfortable/safe to use on very dry, irritated, eczema-prone skin. It’s mainly for children who have had recent flare-ups and moderate eczema severity.
Ciudad Autónoma de Buenos Aire, Ciudad Autónoma de Buenos AireAges 6 months–15 years - NCT05998772Recruiting
How sugar affects Parkinsons symptoms
This study looks at how sugar levels might change the way Parkinsons disease feels. If you have mild to moderate Parkinsons, you may be able to join and help researchers learn more about the role of food in your symptoms.
KielAges 50–80 - NCT06529874Recruiting
Pain, balance, and strength in children with sickle cell
This study looks at how children (ages 9-14) with sickle cell anemia or who are healthy handle pressure, balance, and strength. It aims to understand pain and movement better to help improve care.
GizaAges 9–14 - NCT06752122RecruitingPhase 1
Safety study of RCS-21 in healthy volunteers
This study is testing a new inhaled drug called RCS-21 in healthy volunteers to see if it's safe and how the body handles it. You will be closely monitored and may receive either the drug or a placebo.
HanoverAges 18–64 - NCT06912048Recruiting
How nerves signal the body in health and overweight
This study looks at how your brain sends signals to your body, comparing healthy people and those who are overweight. You'll help researchers understand differences in nerve communication.
UlmAges 18 years+ - NCT06964620RecruitingEarly Phase 1
Sanggua Tablets for prediabetes and mild type 2 diabetes
This trial tests whether Sanggua Tablets, an herbal medicine, can help people with prediabetes or mild type 2 diabetes improve their blood sugar control without needing other medications.
Wuhan, HubeiAges 18–70 - NCT07073781Recruiting
Probiotics for Brain & Blood Sugar in Overweight Young Adults
This study tests whether taking a probiotic (a 'good bacteria' supplement) can help brain function (thinking, memory) and improve blood sugar control in overweight adults who have higher-than-normal blood sugar. If you're between 18-40, overweight, and don't have diabetes, you may be able to join.
Leeds, Greater ManchesterAges 18–40 - NCT07144527Recruiting
NMN supplement for exercise in healthy older adults
This trial tests whether a supplement called nicotinamide mononucleotide (NMN) can help healthy adults aged 60 to 80 improve their exercise tolerance. You'll take the supplement and do supervised cycling sessions to see if it boosts your stamina.
Beverly Hills, CaliforniaAges 60–80 - NCT07269041RecruitingPhase 1/Phase 2
Immune tolerance after liver transplant
This trial tests a way to help your body accept your liver transplant without needing lifelong anti-rejection drugs. It uses your living donor's stem cells to train your immune system to not attack the new liver.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 947 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.