Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 942 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07815678RecruitingPhase 1/Phase 2
Safety study of an oral medication in people with normal or higher weight
This study tests a new oral medication called ACCG-2671 to see how safe it is and how your body handles it. It's an early-stage trial, so the main focus is on safety and tolerability. The study has different parts: one for people with normal weight and one for people with higher weight who are already taking a GLP-1 injection for weight loss.
Cypress, CaliforniaAges 25–75 - NCT07817251RecruitingPhase 3
Switching From Semaglutide to Cagrisema in Type 2 Diabetes
This study looks at how people with type 2 diabetes tolerate switching from a weekly semaglutide injection (like Ozempic or Wegovy) to a new experimental medicine called Cagrisema. The goal is to see if the switch is safe and effective.
Gilbert, ArizonaAges 18 years+ - NCT06207552RecruitingEarly Phase 1
Gene therapy study for children with Fabry disease
This study tests a new gene therapy for children aged 7 to 17 with Fabry disease. The treatment aims to fix the faulty gene that causes the condition, which may help reduce symptoms and prevent organ damage.
ShanghaiAges 7–18 - NCT07812259RecruitingEarly Phase 1
Pain relief injection after parotid gland surgery
This trial tests whether injecting a numbing medicine plus an anti-inflammatory steroid into the parotid gland area after surgery can reduce pain and improve recovery for people having a benign parotid tumor removed.
NîmesAges 18 years+ - NCT07802379Recruiting
Tube feeding tolerance with different blood pressure medications in the intensive care unit
This study looks at how critically ill patients on a breathing tube and receiving nutrition through a tube tolerate their feeding, depending on the dose of medications given to manage their blood pressure. It aims to see if feeding works well while patients are on these medications.
IstanbulAges 18 years+ - NCT07802405RecruitingPhase 1
Testing a new drug alone or with ruxolitinib for myelofibrosis
This trial is testing a new drug called WJ01024, which may help treat myelofibrosis. It can be taken alone or with ruxolitinib, a standard treatment for this condition. The study checks safety and how well it works.
Zhengzhou, HenanAges 3 weeks+ - NCT07805356RecruitingPhase 3
Study of encaleret for chronic hypoparathyroidism
This study tests a new medicine called encaleret for people with chronic hypoparathyroidism, a condition where the body has too little parathyroid hormone, leading to low calcium levels. The medicine aims to improve calcium balance and reduce the need for daily calcium and vitamin D supplements.
Reno, NevadaAges 16 years+ - NCT07804615RecruitingPhase 2
Investigational drug for tremor from Parkinson's disease
This study is testing an investigational drug for Parkinson's-related tremor (shaking). It aims to see if the drug can help reduce tremor in people whose symptoms are not fully controlled by current treatment.
Scottsdale, ArizonaAges 18–65 - NCT07807111RecruitingPhase 1/Phase 2
Gene therapy for advanced rod-cone dystrophy
This study tests a new gene therapy for people with advanced rod-cone dystrophy, a genetic condition that causes progressive vision loss. The treatment is given as an injection into the eye, and the study aims to see if it is safe and if it can help improve or preserve vision.
GhentAges 18 years+ - NCT07801495RecruitingPhase 2
Study of an investigational medicine for moderate to severe psoriatic arthritis
This trial tests an investigational drug (DDY391) in people with moderate to severe psoriatic arthritis. The goal is to see how well it works and if it is safe, which might help reduce joint pain and skin symptoms.
Memphis, TennesseeAges 18–100 - NCT07807865RecruitingPhase 3
Testing a new anxiety medication for safety
This study is testing a new medication for generalized anxiety disorder. It will check if the drug is safe and well-tolerated when taken alone or alongside your current anxiety treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07802964RecruitingPhase 1
Early study of HRS-4139 in healthy adults
This trial studies an investigational medicine called HRS-4139 in healthy adults. The purpose is to see how safe it is, how the body processes it, and how it affects the immune system.
Changsha, HunanAges 18–55 - NCT07803965RecruitingPhase 2
Study of an injection for severe acute pancreatitis
This trial tests an investigational medicine called SGC001 given as an injection to people with severe acute pancreatitis, a serious inflammation of the pancreas. The study aims to see if the drug is safe and helpful, and to gather early information on how it works.
ChengduAges 18–75 - NCT06508216RecruitingPhase 1/Phase 2
New drug combo for early relapsed triple-negative breast cancer
This trial tests experimental drugs for people with triple-negative breast cancer that came back within 12 months of finishing initial treatment. The goal is to see if these drugs are safe and can shrink or slow the cancer.
VillejuifAges 18 years+ - NCT07798609RecruitingPhase 1/Phase 2
Testing SFL-0821 for people with FSHD
This study is testing a new medicine, SFL-0821, to see if it is safe and useful for people with FSHD. It may help if it works, but it is still experimental.
Concord, New South WalesAges 18–65 - NCT07794748RecruitingPhase 3
Pneumococcal vaccine study for adults aged 18 to 49
This study tests a new pneumococcal vaccine to see if it is safe and triggers a good immune response. It may help protect you from infections like pneumonia, but you must not have had any pneumococcal vaccine since age 5.
Birmingham, AlabamaAges 18–49 - NCT06519552RecruitingPhase 1
Gene therapy study for adults with MPS type I
This study tests a new gene therapy called JWK008 for adults with MPS type I. The goal is to see if it is safe and can help improve symptoms. You may be able to join if you are 18 or older and have not had serious side effects from enzyme replacement therapy.
Chengdu, SichuanAges 18 years+ - NCT07792239RecruitingPhase 2
Study of budiodarone for atrial fibrillation
This study tests a new medicine, budiodarone, to help control atrial fibrillation (an irregular heartbeat) in people who haven't been helped by other treatments. It may reduce the time spent in AF and improve symptoms.
GdyniaAges 18–80 - NCT07786779RecruitingPhase 1
Safety study of an injectable drug in healthy adults
This study tests a new injectable medication to see if it is safe and how the body processes it. It is looking for healthy adults to participate and will monitor for side effects and study how the drug works.
Beijing, Beijing MunicipalityAges 18–55 - NCT07789964RecruitingPhase 1
Testing a biosimilar of Taltz in healthy adults
This study tests a biosimilar version of Taltz (SB35) against the original in healthy adults. It checks how the drug is absorbed and if it is safe, without causing serious side effects, helping to ensure the biosimilar works the same way.
Busan, BusanAges 19–55 - NCT07789899RecruitingPhase 1
Safety study of a new investigational drug in healthy volunteers
This trial tests a new medicine to see how the body handles it and whether it is safe. It is for healthy people, not for treating a disease, and helps researchers decide if the drug can move to the next stage of testing.
CambridgeAges 18–55 - NCT07777484RecruitingPhase 1
Study of TRB-001 vaccine for Parkinson's disease after prior immunotherapy
This study tests an experimental vaccine called TRB-001 in people with Parkinson's disease who have already received a previous immunotherapy targeting alpha-synuclein. The goal is to see if the vaccine is safe and how it affects the immune system and the disease.
ViennaAges 18 years+ - NCT07780383RecruitingPhase 1
Single-dose study for healthy adults and early Alzheimer's participants
This trial tests a new investigational drug, BMS-986446, given as a single dose to healthy volunteers and multiple doses to people with early Alzheimer's disease. It aims to understand how the drug moves in the body, its safety, and whether it triggers an immune response, which could help guide future treatment for Alzheimer's.
Anaheim, CaliforniaAges 18–80 - NCT07778524RecruitingPhase 1
Alpelisib challenge test for body weight study
This study tests a single dose of a drug called alpelisib to see how it affects body weight and metabolism. It may help researchers understand how the drug could be used for weight-related conditions.
New York, New YorkAges 18–70
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 942 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.