Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 942 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07770828RecruitingPhase 3
Gene therapy for advanced dry age-related macular degeneration
This trial tests an experimental gene therapy, OCU410, for people with geographic atrophy, an advanced form of dry AMD that causes blind spots in the center of vision. The study aims to see if this treatment can slow down the progression of the disease and help preserve remaining vision.
Phoenix, ArizonaAges 55 years+ - NCT07775391RecruitingPhase 1/Phase 2
Stem cell infusion for early menopause
This trial tests whether a single infusion of stem cells made from human umbilical cord tissue can help women with premature ovarian insufficiency (early menopause) by improving ovarian function and reducing menopause symptoms. Participants will continue their usual hormone replacement therapy during the study.
Beijing, Beijing MunicipalityAges 18–40 - NCT07769489RecruitingPhase 1
Comfort study of larger under-the-skin injections
This study checks if giving larger volumes of liquid under the skin (subcutaneous injection) at different speeds is comfortable and acceptable to healthy people. It aims to see how the body reacts to help make future injections more comfortable for patients.
Gentofte MunicipalityAges 18–64 - NCT07767630RecruitingEarly Phase 1
Targeted radiation therapy for relapsed neuroblastoma
This trial tests a new type of targeted radiation treatment for children and adults with neuroblastoma that has come back or not responded to other treatments. The radiation is attached to a substance that seeks out neuroblastoma cells, aiming to destroy them while limiting harm to healthy tissue.
Chengdu, SichuanAges 1–100 - NCT07765706RecruitingPhase 1
Testing an investigational medicine in healthy volunteers
This study tests a new medicine called INS1033 in healthy people to see if it is safe and how the body handles it. It is an early-stage study and does not involve treating any disease.
Salt Lake City, UtahAges 18–50 - NCT07760467RecruitingPhase 1
Study of an oral medication for safety in healthy adults
This study tests an investigational oral medication called TUL321 in healthy volunteers to see if it is safe and how the body handles it. It may help understand the drug's effects and is an early step in developing a new treatment.
Changsha, HunanAges 18–45 - NCT07758634RecruitingPhase 1/Phase 2
Study of an experimental treatment for high blood pressure
This trial tests a new treatment called CTX340 for high blood pressure that is hard to control even with multiple medications. The study aims to see if it is safe and effective.
Port Orange, FloridaAges 18–75 - NCT07758985RecruitingPhase 1
Testing a pill's safety and effect on mosquitoes in healthy adults
This study tests a new pill called lotilaner for safety and how well it works to kill mosquitoes that carry malaria. It is for healthy adults in Mali and may help future malaria prevention efforts.
BamakoAges 18–55 - NCT07759583Recruiting
Breathing exercises for smog-related pneumonia
This study tests two breathing techniques—Buteyko breathing and incentive spirometry—to see which better improves oxygen levels, breathing difficulty, exercise tolerance, and mucus clearance in people with pneumonia caused by air pollution.
Lahore, Punjab ProvinceAges 25–40 - NCT05674656RecruitingPhase 1/Phase 2
Testing dolutegravir and rilpivirine in HIV-positive children
This study checks how safe and well two HIV medicines work in children ages 6 to under 12. It also measures drug levels in the body to guide dosing and watch for side effects.
Long Beach, CaliforniaAges 6–12 - NCT07749651RecruitingPhase 1
Single-dose safety study of SHR-7012 in healthy adults
This study tests a single dose of a new drug called SHR-7012 in healthy volunteers to check if it is safe and how the body handles it. It is a first-in-human trial, so participants will be closely monitored.
Hangzhou, ZhejiangAges 18–55 - NCT07754474RecruitingPhase 1
Testing a new medicine for overweight or obesity
This study tests a new drug called BI 3034701 to see how well people tolerate different doses. It may help with weight loss and related health issues.
MannheimAges 18–74 - NCT07754331RecruitingPhase 1
Effect of hemodialysis on balcinrenone and dapagliflozin
This study is testing two investigational drugs, balcinrenone and dapagliflozin, in people with kidney failure who are on hemodialysis. The purpose is to see how your body processes these drugs when you are on dialysis, and to make sure they are safe.
Orlando, FloridaAges 18–80 - NCT07755436RecruitingPhase 1
Study of ARR-002 for advanced ovarian or endometrial cancer
This study tests an experimental drug called ARR-002 in people with advanced or metastatic ovarian, primary peritoneal, or fallopian tube cancer that has stopped responding to standard treatments. The goal is to see if it is safe and whether it shrinks tumors.
Orlando, FloridaAges 18 years+ - NCT07749768RecruitingPhase 1
Oral drug for ulcerative colitis safety study
This study tests an investigational oral drug for ulcerative colitis. It is an early-stage trial to check safety and how the drug is processed by the body in both healthy volunteers and patients with active ulcerative colitis.
Miami, FloridaAges 18–55 - NCT07744152RecruitingPhase 1
Testing a new drug for advanced solid tumours
This study tests a new drug called BI 3822971 for people with advanced cancer that has not responded to standard treatments. The goal is to find the best dose that is safe and well-tolerated.
LeuvenAges 18 years+ - NCT07747779Recruiting
Comparing two weight-loss surgeries for very high body weight
This study compares two types of weight-loss surgery to see how they affect hormones after a meal. It may help you choose a surgery that improves your health and weight loss.
Pathum Wan, BangkokAges 18–60 - NCT07734623Recruiting
Ultrasound treatment for severe opioid or amphetamine use disorder
This trial tests a low-intensity focused ultrasound treatment for people with severe opioid or amphetamine use disorder. The ultrasound targets a part of the brain linked to addiction, and the goal is to see if it is safe and helpful.
TaipeiAges 20–50 - NCT07735377RecruitingPhase 1
Study of SHR-6914 for Prostate Cancer
This study tests a new drug called SHR-6914 in men with prostate cancer that has spread. The goal is to see if it is safe and helps shrink or control the cancer, and to learn how the body processes it.
Guangzhou, GuangdongAges 18–80 - NCT07733089RecruitingPhase 1
Testing a new psoriasis drug for safety and effect
This trial tests a new study drug (ZP9830) to see if it is safe and works well for people with plaque psoriasis. You would receive the treatment for 8 weeks, and the study will check how your skin responds.
Leiden, South HollandAges 18–60 - NCT07736638RecruitingPhase 1
Testing safety and tolerability of ABBV-859 in healthy adults
This trial studies a new drug called ABBV-859 in healthy volunteers to see how safe it is and how the body processes it. It helps doctors decide the right dose for future studies.
Anaheim, CaliforniaAges 18–65 - NCT07737743RecruitingPhase 2
Testing DDY391 for Sjögren's disease
This study tests an experimental drug called DDY391 for people with Sjögren's disease. The goal is to see if it can reduce symptoms and improve quality of life, and to check for side effects.
Clearwater, FloridaAges 18–100 - NCT07729839RecruitingPhase 1
Study of ADB116 injection for healthy volunteers
This trial tests a new medicine called ADB116 in healthy people to see how safe it is and how the body processes it. The results will help decide the right dose for future studies.
Guangzhou, GuangdongAges 18–45 - NCT07726147RecruitingPhase 1
Testing a new allergy shot for Japanese cedar pollen
This trial tests a new allergy shot (ITI-9001) for people with Japanese cedar pollen allergy. It aims to see if the shot is safe and can reduce allergy symptoms. The study is for people who have not tried immunotherapy before.
Tokyo, Shinjuku-kuAges 18–65
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 942 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.