Clinical trials
Toxicity clinical trials
Below are recruiting toxicity clinical trials, each written for real people, not researchers. We’re tracking 214 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06124599Recruiting
Early signs of menstrual toxic shock syndrome
This study looks at what happens in the days just before menstrual toxic shock syndrome starts. If you are a young woman who uses tampons or cups and recently got very sick with fever, rash, and low blood pressure during your period, you may be able to join as a case participant.
LyonAges 13–30 - NCT06387901Recruiting
Paclitaxel side effects in breast cancer: activity and body composition
This study looks at how physical activity and body composition affect the side effects of paclitaxel, a chemotherapy drug, in women with stage II or III breast cancer. It aims to help doctors understand who might have more or fewer side effects during treatment.
Brussels, JetteAges 18 years+ - NCT06484530RecruitingPhase 4
Gene-guided NAC to prevent TB drug liver injury
This trial tests whether a medicine called N-acetylcysteine (NAC) can help prevent liver damage caused by standard TB drugs. If you have a higher risk of liver injury based on your genes, you may be given NAC along with your TB treatment.
Bangkok Noi, BangkokAges 18–80 - NCT04920474Recruiting
Share blood and transplant samples for future research
This study builds a library of transplant and related medical samples to help scientists learn how to improve cell therapies and care for marrow injury. You may be included because you are a donor, receive a transplant or cell therapy, or are treated for marrow toxic injury at participating centers.
New Brighton, MinnesotaAges Any age - NCT07314801Enrolling by invitation
Financial impact of cancer in young adults
This study looks at how cancer treatment affects your finances and your recovery, especially for young adults. It involves a phone interview and some questionnaires to understand your experience.
Göttingen, Lower SaxonyAges 18–50 - NCT06086132Recruiting
Preventing heart damage from cancer treatment
This trial tracks how cancer treatments affect the heart. It may help doctors find ways to prevent heart problems during your treatment.
BolognaAges 18 years+ - NCT07061379Recruiting
Patient feedback in first-line lung cancer treatment study
This study collects patient feedback through questionnaires to see if it helps improve outcomes for people with advanced non-small-cell lung cancer starting chemo-immunotherapy. It may help your care team better understand how you are feeling.
Milan, ItalyAges 18 years+ - NCT07226440RecruitingPhase 1/Phase 2
Trial to help firefighters reduce PFAS with a gastrointestinal product
This trial tests if taking a special tablet twice daily can help male firefighters lower PFAS chemicals in their bodies. It involves three visits in the San Francisco Bay Area, at-home blood tests, and weekly text surveys over about 6.5 months.
San Francisco, CaliforniaAges 18 years+ - NCT06452485Recruiting
Re-irradiation with or without hyperthermia, or surgery only for recurrent breast cancer
This trial compares three treatment options for breast cancer that has come back in the chest or lymph nodes after previous radiation. It looks at adding hyperthermia (heating the tumor area) to re-irradiation, versus just re-irradiation or surgery alone, to see which offers better quality of life and survival with fewer side effects.
AmsterdamAges 18 years+ - NCT04700527RecruitingPhase 1/Phase 2
SCFA supplements during belly/pelvis radiation for cancer
This early-phase study tests whether an SCFA (fatty-acid) supplement can improve how patients tolerate radiation to the abdomen or pelvis. Participants are randomly assigned to receive the supplement or a comparison treatment, while they receive their planned radiation.
Chapel Hill, North CarolinaAges 18 years+ - NCT05258448Recruiting
Chemo-radiotherapy for advanced, non-surgical lung cancer
This trial studies treatment that combines chemotherapy and radiation for people with advanced lung cancer that cannot be removed with surgery. It may help improve cure chances for patients who can complete the study tests, including heart scans.
Odense CAges 18 years+ - NCT05417737Recruiting
Ozone therapy for chronic pain when standard treatments fail
This study offers a palliative (comfort-focused) ozone treatment to adults with chronic pain when usual treatments don’t work or are too risky. Researchers will check whether adding ozone can help symptoms and whether it’s safe for selected patients.
Las Palmas, Las PalmasAges 18 years+ - NCT05512169Recruiting
Genetic study in Indian children with newly diagnosed leukemia
This study looks at genetic (DNA) differences to understand acute lymphoblastic leukemia (ALL) in Indian children and how treatments may fit better. You may be able to join if your child is newly diagnosed, meets the study’s treatment plan rules, and provides consent.
New DelhiAges 1–18 - NCT05530655RecruitingEarly Phase 1
Finding the best lisinopril dose to prevent urine side effects
This early study tests which dose of lisinopril works best to help prevent urinary toxicity (urine/burning/urinary side effects) after radiation treatment for prostate cancer. If it’s effective for you, it could make radiation easier to tolerate.
Rochester, New YorkAges 18–70 - NCT05559164RecruitingPhase 2
Statins to protect the heart during HER2 breast cancer treatment
This trial tests whether a cholesterol medicine (a statin) can lower the risk of heart damage in people receiving HER2-targeted breast cancer therapy. If you qualify, you may be given a statin and followed with heart tests and blood work to watch for safety and benefit.
Elizabeth, New JerseyAges 18 years+ - NCT05635929Recruiting
Topical treatment to reduce mouth sores during or after radiation
This study tests a new cream/gel applied to the mouth to lower the chance of severe mouth sores in people receiving radiation for head and neck cancer. It also looks at how treatment affects quality of life using patient questionnaires.
Madrid, MadridAges 18 years+ - NCT05743426Recruiting
Tracking outcomes and side effects in GI and sarcoma cancers
This study follows adults with gastrointestinal cancer or sarcoma to better understand how patients do after treatment and what side effects happen. It may help researchers improve care for future patients by documenting real-world outcomes and toxicities.
Chapel Hill, North CarolinaAges 18 years+ - NCT05761756Recruiting
Study of oxygen side effects in otherwise healthy adults
This study looks at what happens in the body when oxygen levels are too high, to better understand the mechanism of oxygen toxicity. You may be eligible if you are a healthy, non-smoking adult without certain medical conditions.
Durham, North CarolinaAges 18–45 - NCT05885048Recruiting
Testing how cancer treatments affect future fertility
This study looks at how treatments that can harm ovaries or testicles (like certain chemotherapy, radiation, and immune therapies) may affect fertility. It may help you and others by measuring hormone levels (and in some cases sperm) before and during/after treatment.
BernAges 14–50 - NCT05981573Recruiting
Measuring methadone doses for chronic pain
This trial is for people with chronic pain who take daily methadone. It aims to measure how much methadone is in your body to help doctors find the right dose.
Lemon Grove, CaliforniaAges 18–70 - NCT06274268Recruiting
Sarcopenia and cancer treatment side effects study
This study looks at how muscle loss (sarcopenia) might affect side effects from cancer treatments. If you are starting a new cancer treatment, a CT scan before treatment can help doctors predict your risk of side effects.
ChambéryAges 18 years+ - NCT06119490RecruitingEarly Phase 1
Methylprednisolone and JAK inhibitor for severe skin reaction
This trial tests a combination of a steroid (methylprednisolone) and a JAK inhibitor to treat toxic epidermal necrolysis, a severe skin reaction. The goal is to see if adding the JAK inhibitor helps improve outcomes and safety.
Fuzhou, FujianAges 18–70 - NCT06503380Recruiting
Managing blood side effects from breast cancer targeted drugs
This study looks at how well current methods manage low blood cell counts (low platelets, low white blood cells, and low red blood cells) that can happen from targeted therapies for breast cancer. If you have breast cancer and are getting or have gotten a targeted therapy, this trial could help improve care for side effects like these.
Shanghai, Not US/CanadaAges Any age - NCT06639165Recruiting
Radiation outcomes in children and young adults with pediatric cancers
This study looks back at past patients and follows new patients to understand how well radiation therapy works and what side effects it causes in children, teens, and young adults (and some older adults with childhood-type cancers) treated at the Pediatric Radiotherapy Unit in Aviano. It helps doctors learn more about the benefits and risks of radiation for these cancers.
Aviano, PordenoneAges Any age
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Common questions
- Are there clinical trials for toxicity?
- Yes. Clin2 currently lists 214 recruiting toxicity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a toxicity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a toxicity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.