Clinical trials
Toxicity clinical trials
Below are recruiting toxicity clinical trials, each written for real people, not researchers. We’re tracking 216 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04754672Recruiting
Exercise training to improve outcomes in advanced colon cancer
This trial studies whether supervised exercise—either aerobic fitness training or muscle-strength training—can improve outcomes for people with metastatic colorectal cancer. It compares which approach is most helpful and checks whether it’s safe during first-line chemotherapy.
's-HertogenboschAges 18 years+ - NCT04807114Recruiting
Blood or tissue testing to find markers for lung cancer treatment
This study uses detailed “single-cell” testing to look for markers that can predict how well immunotherapy works and what side effects may happen. It is for people with non-small cell lung cancer starting standard first-line treatment.
LeuvenAges 18–120 - NCT04807127Recruiting
Testing blood and lung fluid markers for lung side effects
This study tries to find early warning markers in lung fluid collected during a bronchoscopy (a camera test of the airways). The goal is to better spot and understand lung inflammation that can happen after immune checkpoint cancer treatments.
Leuven, Flemish BrabantAges 18–120 - NCT04822077Recruiting
Proton beam treatment for thymus tumors
This trial studies proton radiotherapy (a type of radiation) for cancers of the thymus, like thymoma or thymic carcinoma. It may help improve tumor control while limiting radiation exposure to nearby organs.
Umeå, NorrlandAges 18 years+ - NCT04831437RecruitingPhase 2
Tested split-course chemo radiation for cervical cancer side effects
This Phase 2 trial looks at a “split” (hypo-fractionated) schedule of chemotherapy plus radiation for cervical cancer, followed by brachytherapy. It aims to see how well the treatment works and what side effects happen, especially toxicity.
TehranAges 18–85 - NCT04831970Recruiting
Ablative radiation after prostate surgery for early recurrence
This trial studies a targeted, high-intensity radiation approach given after prostate removal surgery when prostate cancer seems to be coming back locally. It may help control the disease in the pelvis while avoiding treatment that could cause more side effects.
Rozzano, MIAges 18–90 - NCT04856488RecruitingPhase 3
Lugol’s iodine solution before thyroid surgery for overactive thyroid
This trial tests whether taking Lugol’s iodine solution before thyroid surgery is safe and helpful for people with Graves’ disease or toxic nodular goiter (overactive thyroid). It may be aimed at improving surgical readiness and outcomes by reducing thyroid activity before the operation.
Solna, Stockholm CountyAges 18–75 - NCT04902846Recruiting
Checking kidney side effects from immune cancer medicines
This study looks at how immune checkpoint medicines (sometimes combined with other treatments like chemotherapy) may affect the kidneys. It may help doctors better prevent or manage kidney side effects in people starting these therapies.
SalamancaAges 18–100 - NCT06888817RecruitingPhase 3
Bevacizumab vs steroids for brain radiation injury
This trial tests if bevacizumab works better than steroids for people with brain swelling caused by radiation. If you have this condition and meet certain health requirements, you may join.
AmsterdamAges 18 years+ - NCT05061342Recruiting
Cancer or healthy volunteers share health and imaging survey data
This study collects information about how cancer care affects daily life, treatment side effects, and quality of life, and it stores imaging and related data for future research. You might be able to take part if you’re scheduled for treatment at the center (or you’re a healthy volunteer) and can complete the questionnaires.
Shenzhen, GuangdongAges 18 years+ - NCT05127148Recruiting
Real-world study of pediatric-like treatment for Ph-negative ALL
This study follows how well a “pediatric-style” treatment plan works in teens and young adults with Ph-negative acute lymphoblastic leukemia (ALL) in real-world care. It mainly aims to understand outcomes and safety for patients who fit the specific leukemia and health criteria.
Paraná, Entre Ríos ProvinceAges 18–40 - NCT05165056Recruiting
Light therapy to prevent vaginal side effects from radiation
This study tests whether photobiomodulation (a light-based therapy) can help prevent and lessen vaginal problems caused by radiation for endometrial cancer. If you get radiation to the pelvis, the trial aims to improve comfort and reduce tightening or damage over time.
Genk, LimburgAges 18 years+ - NCT05203250Recruiting
Registry for people treated with heavy particles at CNAO
This registry collects information from people who received heavy particle treatments at the CNAO center. It helps researchers understand outcomes over time, as long as you can understand the study and agree in writing.
PaviaAges Any age - NCT05223413Recruiting
Remote arm treatment to protect the heart during chemo
This trial studies whether a simple “remote conditioning” treatment on the arm can help protect the heart while you receive chemotherapy that includes anthracyclines. If you’re at higher risk for heart damage from chemo, this may reduce risk and help monitor heart function over time.
AarhusAges 18–99 - NCT05245487Recruiting
Study of blood samples in older people with relapsed lymphoma
This study looks at blood (“hematopoietic”) information in people age 60+ with relapsed B-cell non-Hodgkin lymphoma who need an additional round of treatment. It may help researchers understand changes in the body during active lymphoma therapy.
CopenhagenAges 60 years+ - NCT05269485RecruitingPhase 1/Phase 2
Hypofractionated radiation for stage III lung cancer
This trial studies a radiation treatment schedule called “hypofractionated radiotherapy” for people with locally advanced (stage III) non-small cell lung cancer who cannot have surgery. It aims to see whether this radiation approach works well and is tolerable for your cancer stage.
Hefei, AnhuiAges 18–70 - NCT05331066Recruiting
Tracking side effects from immunotherapy using multiple tests
This study looks at how side effects happen in people receiving immune checkpoint inhibitor immunotherapy for solid cancers. It uses multiple types of tests to better understand these toxicities and may help improve safety and care in the future.
Chelsea, LondonAges 18 years+ - NCT05345587Recruiting
Digital monitoring plus proactive medication review during oral cancer treatment
This trial tests whether combining regular medication safety checks with electronic tracking of side effects can improve quality of life and help reduce economic burden for people taking cancer pills. It’s for people starting oral cancer therapy and using connected technology to report symptoms.
Brive-la-GaillardeAges 18 years+ - NCT05354765Recruiting
Collect immune cells by lymphapheresis to study cancer response
This trial studies how changing your immune system (with earlier treatments) affects cancer by collecting immune cells from your blood using a process called lymphapheresis. It may help researchers find better ways to monitor immune-related responses and side effects.
ParisAges 18 years+ - NCT05394428Recruiting
Study sexual side effects after pelvic radiation in women
This study looks at sexual side effects after pelvic radiation for certain cancers of the female reproductive organs. It may help improve how these problems are understood and managed after treatment.
Atlanta, GeorgiaAges 18 years+ - NCT05426252RecruitingPhase 1/Phase 2
Lower-toxicity bone marrow conditioning for high-risk thalassemia
This trial tests a modified, lower-toxicity preparation (conditioning) before a bone marrow transplant in children and teens with high-risk thalassemia. It aims to reduce treatment side effects while still allowing transplant success for people who need a donor.
Toronto, OntarioAges 1–18 - NCT05465031RecruitingPhase 4
Testing heart-protection medicine during breast cancer treatment
This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.
Opole, Opole VoivodeshipAges 18 years+ - NCT05590130Recruiting
Test two oxygen targets using different oxygen monitors
This study compares how much oxygen is needed and how well oxygen levels stay in a safe range after heart surgery in the ICU. It also tests whether using different oxygen monitors affects oxygen flow and oxygenation.
Québec, QuebecAges 18 years+ - NCT05626530RecruitingPhase 4
Letermovir to prevent CMV after transplant illness
This trial studies whether letermovir can help prevent CMV (a common virus after transplant) from coming back after you’ve already been treated. If you qualify, you may be offered letermovir as “secondary prevention” and followed for about 6 months.
Boston, MassachusettsAges 18–75
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Common questions
- Are there clinical trials for toxicity?
- Yes. Clin2 currently lists 216 recruiting toxicity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a toxicity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a toxicity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.