Clinical trials
Toxicity clinical trials
Below are recruiting toxicity clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05959720Recruiting
Teen-to-adult ALL study using a pediatric chemotherapy plan
This trial tests a treatment plan for newly diagnosed acute lymphoblastic leukemia (ALL) in people ages 16 to 50. It aims to see how well a “pediatric-style” regimen works, but it only fits certain genetic and health profiles.
São Paulo, São PauloAges 16–50 - NCT07138222Recruiting
Immune therapy and fertility in women and men with melanoma
This study looks at how immune checkpoint inhibitors (a type of immunotherapy) affect fertility and hormone health in premenopausal women and men with melanoma. It aims to understand and manage these side effects while you receive treatment.
Sydney, New South WalesAges 18–60 - NCT07095439RecruitingPhase 2
Sandwich treatment for stage 2 and 3 rectal cancer
This trial tests a new way of giving radiation and chemotherapy before surgery for rectal cancer that hasn't spread. It aims to see if this 'sandwich' approach is safe and works better than standard treatment.
CairoAges 18–70 - NCT07077239Recruiting
Adaptive radiation after prostate surgery to lower side effects
This trial tests a precise, short-course radiation treatment (stereotactic body radiotherapy) after prostate removal surgery that adapts to your body each day to reduce side effects. It is for people whose prostate cancer has high-risk features or a rising PSA after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT05655780Recruiting
Irinotecan care guided by tumor genes and gut bacteria
This study looks at whether a patient’s tumor genetic makeup and gut bacteria activity can predict how well irinotecan-based treatment works and what side effects they might have. It may help personalize treatment to improve survival and quality of life for people with metastatic or unresectable colon cancer.
Maastricht, LimburgAges 18 years+ - NCT07057284Enrolling by invitation
Dentofacial effects of proton therapy for childhood head and neck cancer
This study looks at how proton beam therapy (a precise type of radiation) affects the teeth and face in children and teens who had head or neck cancer. The goal is to understand these long-term effects and help improve future care.
ManchesterAges 2–32 - NCT07064330Recruiting
Blood test for immune markers in skin cancer patients on cemiplimab
This trial is testing whether a new blood test can predict how well the drug cemiplimab works for skin cancer and if it causes side effects. It may help doctors better match treatments to patients.
Salamanca, SalamancaAges 18 years+ - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT07030998Recruiting
Using smartwatch data to find early signs of infection in kids with cancer
This trial uses an Apple Watch and a smartphone app to track health data and detect early signs of infection in children and teens getting cancer treatment. The goal is to catch problems early so they can be treated quickly.
Parkville, VictoriaAges 5–18 - NCT07018622RecruitingPhase 2
Protecting kidneys from platinum chemotherapy damage
This trial tests a way to protect your kidneys while you receive platinum-based chemotherapy (cisplatin or carboplatin) for a solid tumor. It may help reduce the risk of kidney damage so you can complete your treatment more safely.
México, TlalpanAges 18 years+ - NCT04496024Recruiting
How ofloxacin levels may affect older adults with bone infections
This study looks at whether blood levels of the antibiotic ofloxacin in people over 65 are linked to side effects, in older adults hospitalized for bone and joint infections. It may help doctors choose safer doses, especially when switching from IV treatment to pills.
AmiensAges 65 years+ - NCT06311968RecruitingPhase 2
Proton radiation after surgery for thymus tumors
This trial tests a type of precise radiation called proton therapy after surgery for thymus tumors. It may help reduce the chance of the tumor coming back while limiting side effects to nearby organs.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06950073Recruiting
Second radiation treatment for lung cancer in the chest
This study tests whether giving a second course of radiation to the chest (called retreatment) can control lung cancer that has come back or a new cancer that started there. People who have already had radiation to their chest and are healthy enough for more may be eligible.
Aarhus, JutlandAges Any age - NCT06923397Recruiting
Stopping long sitting time during lymphoma chemo (iSTAND Trial)
This study looks at whether taking short, frequent breaks from sitting can help people with lymphoma who are starting chemotherapy feel better and have fewer side effects. If you join, you'll get a wearable activity tracker and text reminders to stand up and move gently throughout your day.
Boston, MassachusettsAges 18 years+ - NCT06036706Recruiting
Radiation types and thinking skills for skull base meningioma
This study compares different radiation methods for treating a slow-growing, non-cancerous brain tumor at the base of the skull. It aims to see which approach best protects memory and thinking abilities.
CaenAges 20–65 - NCT06909201Recruiting
Lung MRI scan to study radiation treatment effects
This study uses a special MRI scan with xenon gas to see how radiation therapy affects your lungs. It may help doctors better understand treatment response and side effects.
Houston, TexasAges 18 years+ - NCT05933733Recruiting
Salvage treatment for breast cancer that returned locally
This trial looks at how well “salvage” treatments work for breast cancer that has come back only in the local area (like the chest wall or nearby lymph nodes), without spreading to distant organs. It also tracks side effects to better understand the risks and benefits for patients who need additional treatment.
SeoulAges 18–100 - NCT06888817RecruitingPhase 3
Bevacizumab vs steroids for brain radiation injury
This trial tests if bevacizumab works better than steroids for people with brain swelling caused by radiation. If you have this condition and meet certain health requirements, you may join.
AmsterdamAges 18 years+ - NCT06055179Recruiting
Herbal medicine for diarrhea from irinotecan chemo
This study tests if a Chinese herbal formula (XCHT) can reduce diarrhea caused by the chemo drug irinotecan. If you are getting irinotecan and already had troublesome diarrhea, you may be able to join and get supportive treatment.
Guangzhou, GuangdongAges 18–75 - NCT06868459Enrolling by invitation
Study of PED-TAE treatment for thyroid disease
This study tracks people who have already received a new type of thyroid treatment called PED-TAE (pressure-enabled embolization) using the TriNav system. It aims to see how well this procedure works for various thyroid conditions, including overactive thyroid, large goiters, and benign nodules causing symptoms.
Jacksonville, FloridaAges 18–89 - NCT04053439Recruiting
Testing blood-clone risk to prevent chemotherapy complications
This study looks at a specific genetic/production change in blood-forming cells (“clonal hematopoiesis”) to understand who is more likely to have complications from lymphoma chemotherapy. It may help doctors predict risk and possibly reduce harmful side effects.
Toronto, OntarioAges 60 years+ - NCT06840652Enrolling by invitation
Baclofen for alcohol withdrawal in liver disease
This trial tests if baclofen, a medicine for alcohol dependence, is safe and works for people with chronic liver disease who are actively drinking. It may help you stop drinking alcohol safely.
Sabadell, BarcelonaAges 18–75 - NCT06830863RecruitingPhase 1/Phase 2
Skin rash treatment for people taking cancer drugs
This study tests a new cream, ATR04-484, to see if it can help with skin rashes caused by certain cancer medications (EGFR inhibitors, KRAS inhibitors, or MEK inhibitors). If you have a moderate to severe rash on your face or other areas from these drugs, this trial may offer a new way to ease your symptoms.
Hot Springs, ArkansasAges 18 years+ - NCT06831669Recruiting
Predicting rectal cancer treatment response and side effects
This study uses metabolomics (analysis of small molecules in your body) to predict how well your rectal cancer will respond to treatment and whether you may experience side effects. It focuses on patients receiving total neoadjuvant therapy (treatment before surgery).
Guishan, TaoyuanAges 20 years+
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Common questions
- Are there clinical trials for toxicity?
- Yes. Clin2 currently lists 208 recruiting toxicity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a toxicity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a toxicity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.