Clinical trials
Toxicity clinical trials
Below are recruiting toxicity clinical trials, each written for real people, not researchers. We’re tracking 216 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05639933RecruitingPhase 2
Topical cream for EGFR inhibitor skin rash in cancer patients
This Phase 2 study tests a topical cream (HT-001) to treat skin rashes caused by EGFR inhibitors. It aims to see whether the cream is safe and can reduce rash symptoms and discomfort.
Irvine, CaliforniaAges 18 years+ - NCT05643014Recruiting
Study of chemical exposure in firefighters’ urine
This observational study looks at how common environmental chemicals may build up in firefighters, measured with urine samples before and after exposure. It may help researchers understand potential health risks in this job—even though you won’t receive study medicine.
Minneapolis, MinnesotaAges 18 years+ - NCT05652673Recruiting
Stopping immunotherapy after a good melanoma response
This trial studies whether it’s safe to stop nivolumab (an immunotherapy) after your melanoma has responded well to initial treatment with ipilimumab plus nivolumab. It may help some people avoid ongoing treatment side effects while still keeping the cancer controlled.
RotterdamAges 18 years+ - NCT05655780Recruiting
Irinotecan care guided by tumor genes and gut bacteria
This study looks at whether a patient’s tumor genetic makeup and gut bacteria activity can predict how well irinotecan-based treatment works and what side effects they might have. It may help personalize treatment to improve survival and quality of life for people with metastatic or unresectable colon cancer.
Maastricht, LimburgAges 18 years+ - NCT05727605Recruiting
Thinking changes after radiotherapy for brain and skull-base tumors
This trial studies how radiotherapy affects memory and thinking in adults with certain brain or skull-base tumors. It may help doctors understand who is most likely to have thinking changes and how to monitor or support patients.
GhentAges 18 years+ - NCT05817617Recruiting
Vitamin D use in head and neck cancer
This study looks at how taking vitamin D may affect side effects (toxicity) and outcomes in people with locally advanced head and neck squamous cell cancer. It may help improve comfort during treatment and track whether vitamin D changes prognosis.
Barletta, BATAges 18 years+ - NCT05840575Recruiting
Study of thinking changes in young people during cancer treatment
This study looks at how thinking and memory may change in children and young adults after a new cancer diagnosis, especially around chemotherapy. It may help doctors better understand and track brain-related side effects early.
CopenhagenAges 7–29 - NCT05921279Recruiting
Study heart events in people with breast cancer
This study looks at what heart-related side effects happen in women with breast cancer who are planned to receive chemotherapy. It may help doctors better understand and monitor these risks during treatment.
GalwayAges 18–90 - NCT05933733Recruiting
Salvage treatment for breast cancer that returned locally
This trial looks at how well “salvage” treatments work for breast cancer that has come back only in the local area (like the chest wall or nearby lymph nodes), without spreading to distant organs. It also tracks side effects to better understand the risks and benefits for patients who need additional treatment.
SeoulAges 18–100 - NCT05959720Recruiting
Teen-to-adult ALL study using a pediatric chemotherapy plan
This trial tests a treatment plan for newly diagnosed acute lymphoblastic leukemia (ALL) in people ages 16 to 50. It aims to see how well a “pediatric-style” regimen works, but it only fits certain genetic and health profiles.
São Paulo, São PauloAges 16–50 - NCT05968677Recruiting
Amino acids and flavonoids to reduce chemotherapy side effects
This trial tests whether a specific nutrition supplement (amino acids and flavonoids) can lessen chemotherapy side effects, support nutrition, and improve quality of life in people with non-metastatic breast cancer. It focuses on women who are receiving certain chemotherapy medicines and can eat by mouth and attend regular visits.
PaviaAges 50–70 - NCT06006806Recruiting
Proton therapy skin effects study for breast cancer
This study looks at how proton therapy affects the skin in people being treated for early-stage breast cancer. It aims to understand skin reactions better so doctors can reduce side effects.
Knoxville, TennesseeAges 18 years+ - NCT06029218Recruiting
Comparing one vs two proton beams for bone and spine tumors
This trial is testing whether using only one proton beam per day is as safe and effective as using two beams for treating certain bone and spine tumors. It may help reduce treatment time and side effects.
NiceAges 18 years+ - NCT06033183Recruiting
Study of radiation sensitivity in children with cancer
This study looks at how children's bodies respond to radiation therapy for certain cancers. By analyzing blood samples, researchers hope to learn why some children experience more side effects, which could help personalize future treatments.
CaenAges 3–18 - NCT06036706Recruiting
Radiation types and thinking skills for skull base meningioma
This study compares different radiation methods for treating a slow-growing, non-cancerous brain tumor at the base of the skull. It aims to see which approach best protects memory and thinking abilities.
CaenAges 20–65 - NCT06039735Recruiting
Heart ultrasound study in multiple myeloma treated with RVd
This study looks at how a new heart ultrasound test can measure heart side effects and overall outcomes in people with multiple myeloma who are treated with the RVd drug combination. It may help doctors better understand heart risks during treatment.
Jinan, ShandongAges 18–70 - NCT06041477RecruitingPhase 3
Combining treatments for liver cancer before surgery
This study tests whether giving targeted therapy and immunotherapy at the same time or one after the other is better for shrinking liver tumors that can't be removed right now but might be removable after treatment.
Guangzhou, GuangdongAges 18–75 - NCT06044623RecruitingPhase 3
Tailoring cancer pill dosing for older adults with breast cancer
This trial is testing whether adjusting the dose of a targeted therapy (CDK 4/6 inhibitor) based on a geriatric assessment can be as effective and safer for people aged 70 and older with advanced hormone receptor-positive, HER2-negative breast cancer. It aims to find the best dose to balance benefits and side effects.
HelsinkiAges 70 years+ - NCT06052683Recruiting
Comparing radiation side effects for low-risk prostate cancer
This trial compares two types of radiation therapy (SBRT and LDR brachytherapy) for men with low-risk or favorable intermediate-risk prostate cancer. The goal is to see which treatment causes fewer side effects.
Québec, QuebecAges 18 years+ - NCT06055179Recruiting
Herbal medicine for diarrhea from irinotecan chemo
This study tests if a Chinese herbal formula (XCHT) can reduce diarrhea caused by the chemo drug irinotecan. If you are getting irinotecan and already had troublesome diarrhea, you may be able to join and get supportive treatment.
Guangzhou, GuangdongAges 18–75 - NCT06059586Recruiting
Pre-hab program for women getting pelvic radiation for cancer
This trial tests a pre-rehabilitation (pre-hab) program to help women stay stronger before and during pelvic radiation for certain cancers. The goal is to see if it improves quality of life and reduces treatment side effects.
Avon, IndianaAges 18 years+ - NCT06081517Recruiting
Study of fairness in genetic cancer testing
This study looks at how well precision medicine (treatments based on your tumor's genes) is used for people with cancer. Researchers want to see if there are differences in who gets this kind of testing and treatment, so they can make it more fair for everyone.
Indianapolis, IndianaAges 18 years+ - NCT06114589Recruiting
Predicting radiation side effects in breast cancer
This study is looking for biomarkers (genetic clues) to predict how patients will react to radiation after breast-conserving surgery. It aims to create a model that can personalize treatment to reduce side effects.
Aviano, PordenoneAges 18 years+ - NCT06159660Recruiting
Lung Imaging to Reduce Radiation Side Effects
This trial tests a new way to plan radiation therapy for lung cancer by using a special imaging technique (functional lung imaging) to see which parts of your lungs work best. The goal is to reduce damage to healthy lung tissue while still targeting the cancer.
St Leonards, New South WalesAges 18 years+
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Common questions
- Are there clinical trials for toxicity?
- Yes. Clin2 currently lists 216 recruiting toxicity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a toxicity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a toxicity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.