Clinical trials · Massachusetts
Traumatic Brain Injury clinical trials in Massachusetts
We’re tracking 12 recruiting traumatic brain injury studies with a site in Massachusetts — including Phase 1, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT04124029Recruiting
Study how mild brain injuries may relate to dementia
This study looks at how past mild traumatic brain injury may contribute to brain changes seen in chronic traumatic encephalopathy (CTE) and Alzheimer’s disease (AD). It may help researchers understand risk and brain markers by comparing people with mild or moderate TBI, people with mild memory problems, and healthy controls.
Boston, MassachusettsAges 30–90 - NCT04400266RecruitingPhase 4
Buspirone and melatonin for depression after a brain injury
This trial studies whether the medicines buspirone and melatonin can reduce depression symptoms in people who had a mild or moderate traumatic brain injury (TBI) at least 3 months ago. It may help if you have ongoing depression after TBI and can safely take study medications and attend regular visits, including MRI scans.
Charlestown, MassachusettsAges 18–64 - NCT06109909Recruiting
Brain training for light sensitivity after mild head injury
This study tests if a type of brain training called neurofeedback can help reduce sensitivity to light in people who have had a mild traumatic brain injury, also known as a concussion, at least 6 months ago.
Boston, MassachusettsAges 18–65 - NCT06839079Recruiting
Brain training for trauma survivors with head injury
This study tests a cognitive rehabilitation program for people with traumatic brain injury who have also experienced war, violence, or other trauma. It aims to improve memory and thinking skills using exercises and strategies.
Boston, MassachusettsAges 18–65 - NCT06504238Recruiting
Non-invasive monitoring for acute brain injury
This trial tests special cameras and sensors that check your brain without surgery. It may help doctors watch for brain swelling and other problems more safely.
Boston, MassachusettsAges 18 years+ - NCT06848140Recruiting
Brain stimulation for word-finding problems after TBI
This study tests whether non-invasive brain stimulation can help people with chronic traumatic brain injury (TBI) find words more easily. It involves sessions at Beth Israel Deaconess Medical Center in Boston.
Boston, MassachusettsAges 18–85 - NCT05826912Enrolling by invitationPhase 2
Testing new treatment for acute brain injury after a fall or hit
This study tests an investigational treatment to improve outcomes after a recent non-penetrating traumatic brain injury (like a fall or car crash). It uses early CT/MRI imaging and a blood test soon after injury to see who benefits and how well the treatment works.
Boston, MassachusettsAges 18–65 - NCT06860828Enrolling by invitation
Football players and brain health study: DIAGNOSE CTE
This study looks at brain changes in former college and professional football players, people with memory problems, and healthy controls. It aims to learn more about chronic traumatic encephalopathy (CTE) and Alzheimer's disease.
Boston, MassachusettsAges 50 years+ - NCT04296604Recruiting
tDCS brain stimulation to improve thinking and mood
This study tests whether a non-surgical brain stimulation called tDCS can improve “executive function,” which means skills like planning, focus, and decision-making. It is designed for people with several mental health and substance-use conditions, and it may help you if those skills are affected by your diagnosis.
Boston, MassachusettsAges 18–65 - NCT06142435Recruiting
Eye scan to detect and monitor mild brain injury
This study uses a retinal scanner to see if it can detect and track brain injury after a mild head trauma (concussion). If you are between 18 and 45 years old and had a head injury within the past two weeks, this test might help doctors learn more about your injury without invasive procedures.
Boston, MassachusettsAges 18–45 - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT06883006RecruitingPhase 1
Sleep extension study for recent concussion recovery
This trial tests whether extending sleep helps young adults recover from a recent concussion. If you are 18-35 and had your first or second concussion 2-3 weeks ago, you may be able to join.
North Andover, MassachusettsAges 18–35
Traumatic Brain Injury trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting traumatic brain injury studies listed above.
- Massachusetts General Hospital · 4 studies
- VA Boston Healthcare System Jamaica Plain Campus · 3 studies
- Boston Medical Center · 2 studies
- Beth Israel Deaconess Medical Center
- Boston University
- Merrimack College
What taking part in a traumatic brain injury study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Traumatic Brain Injury trials in other states
Common questions
- Are there traumatic brain injury clinical trials in Massachusetts?
- Yes. We're currently tracking 12 recruiting traumatic brain injury studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a traumatic brain injury study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a traumatic brain injury trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New traumatic brain injury studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.