Clinical trials
Stress Disorders, Traumatic clinical trials
Below are recruiting stress disorders, traumatic clinical trials, each written for real people, not researchers. We’re tracking 276 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06479447Recruiting
Patient-reported PTSD screening study
This trial is testing a simple way to check for PTSD symptoms using patient-reported questionnaires. It aims to help people who haven't been screened recently get the care they need.
Chicago, IllinoisAges 18 years+ - NCT06419959Recruiting
NightWare app for veterans with PTSD and sleep problems
This study tests a smartwatch app called NightWare that may reduce nightmares and improve sleep in veterans with PTSD. It could also help heart health by improving sleep quality.
Aurora, ColoradoAges 22–88 - NCT06381180RecruitingPhase 1/Phase 2
Cannabis for Veterans with PTSD
This study is testing whether cannabis can help veterans with PTSD feel better. It is for veterans who have used cannabis before and currently have PTSD symptoms.
Detroit, MichiganAges 19–69 - NCT06332209Recruiting
Telehealth vs. in-person therapy for trauma in Puerto Rican youth
This trial compares two ways of giving a type of therapy called Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) to children and teens in Puerto Rico who have been through a traumatic event and have post-traumatic stress symptoms. One group receives therapy in person at a clinic, and the other group receives therapy through video calls (telehealth), to see which works better.
Charleston, South CarolinaAges 7–18 - NCT06294106Recruiting
Brain stimulation for PTSD in veterans and first responders
This study tests a new type of brain stimulation (eTMS) to help reduce PTSD symptoms in veterans and first responders. It uses an MRI to guide the treatment, and aims to see if it can improve your quality of life.
Roanoke, VirginiaAges 18–65 - NCT06266364Recruiting
Vagus nerve stimulation for treatment-resistant PTSD
This study tests if stimulating the vagus nerve with an implanted device can help adults with chronic PTSD who haven't gotten better with standard treatments. You would have the device implanted and then follow the study plan for several months.
Austin, TexasAges 22–79 - NCT06218381Recruiting
Brief exposure for PTSD in combat veterans
This study tests a very brief exposure therapy to help U.S. combat veterans with PTSD. It is designed for veterans who have not had recent mental health treatment and experienced combat trauma within the last 10 years.
Los Angeles, CaliforniaAges 18–50 - NCT06194851RecruitingPhase 2
Oxytocin nasal spray plus couples therapy for Veterans with PTSD
This study tests whether a nasal spray of oxytocin (a natural hormone) can boost the effects of a brief couples therapy for Veterans with PTSD. You and your partner would receive either the spray or a placebo (inactive spray) during therapy sessions to see if it helps reduce PTSD symptoms and improve relationship satisfaction.
San Diego, CaliforniaAges 18 years+ - NCT06162741Recruiting
Brief mindfulness training for Veterans in primary care
This study tests whether brief mindfulness training offered in VA primary care can help Veterans with symptoms of PTSD, depression, or anxiety. It aims to see if this approach works well in everyday clinic settings.
Phoenix, ArizonaAges 18 years+ - NCT06179485Enrolling by invitation
Ketamine vs. Etomidate for emergency breathing tube: long-term study
This study compares how two common medicines (ketamine and etomidate) used during emergency breathing tube placement affect long-term recovery. It is only for patients already enrolled in another related trial.
Birmingham, AlabamaAges 18 years+ - NCT05560113Recruiting
Study uses brain stimulation to disrupt fear memory in PTSD
This study tests a brain stimulation approach to affect how fear memories “stick” after they are formed. If you have PTSD, it may help reduce fear-related learning, but you must meet several safety and health criteria.
Atlanta, GeorgiaAges 18–65 - NCT03755401Recruiting
Therapy trial for PTSD after prior treatment didn’t fully help
This trial studies a specific talk-therapy approach (psychodynamic psychotherapy) for people with post-traumatic stress disorder (PTSD) who still have significant symptoms despite prior treatment. You may be able to join if your PTSD symptoms are in a moderate range and you can safely participate without urgent safety risks or certain other conditions.
New York, New YorkAges 18–70 - NCT05788302Recruiting
Studying prolonged exposure for PTSD and how it helps
This trial studies how a therapy called “prolonged exposure” works for people with post-traumatic stress disorder (PTSD). You may be able to join if you have PTSD, are interested in starting prolonged exposure, and meet other safety and participation rules.
Boston, MassachusettsAges 18 years+ - NCT06044675RecruitingPhase 2
MDMA plus therapy for PTSD – a study with a partner
This study tests whether MDMA, combined with a type of talk therapy called CBCT (cognitive behavioral conjoint therapy), is more effective than CBCT alone for treating PTSD. You and a close partner will both participate in therapy sessions and take MDMA together.
Toronto, OntarioAges 18–80 - NCT06035809Recruiting
Smart treatment study for PTSD using brain activity feedback
This study tests a new therapy called SMART, which uses brain imaging to help regulate arousal linked to PTSD. It aims to see if combining brain feedback with therapy reduces PTSD symptoms.
London, OntarioAges 18–65 - NCT06002633Recruiting
Alcohol effects and brain responses in PTSD
This study explores how people with PTSD respond to alcohol and how their brains handle approach or avoidance situations. You may participate if you drink alcohol occasionally and are between 21 and 60 years old.
Austin, TexasAges 21–60 - NCT05974631Recruiting
Treatments for suicidal Veterans with PTSD
This study tests two types of therapy to help Veterans with PTSD who are struggling with suicidal thoughts and self-harm. It compares a treatment called DBT (Dialectical Behavior Therapy, which helps with emotions) with another called PE (Prolonged Exposure, which helps with trauma).
Minneapolis, MinnesotaAges 18 years+ - NCT05929911Recruiting
Talk therapy for PTSD in people living with HIV
This trial tests whether trauma-focused psychodynamic talk therapy can reduce symptoms of post-traumatic stress disorder (PTSD) in people who also live with HIV. It may help by offering structured therapy alongside stable medication.
The Bronx, New YorkAges 18–65 - NCT05600868Enrolling by invitation
Testing dual attention during EMDR therapy for PTSD
This study tests whether adding “dual attention” to EMDR therapy helps people with high PTSD symptoms. If you have significant PTSD symptoms, this approach may improve how well the therapy works, but it depends on safety and recent treatment history.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05563805Recruiting
Virtual reality adventure training for movement and fitness
This study uses a virtual reality “adventure” game that gets you moving to train exercise skills and coordination. It’s designed for U.S. military veterans who can walk on their own and don’t have certain vision, balance, or medical limits.
Arlington, TexasAges 18–45 - NCT05441280RecruitingPhase 2
Pimavanserin to improve sleep in veterans with PTSD
This Phase 2 trial studies pimavanserin, a medicine meant to improve insomnia, in veterans who also have PTSD. It may help reduce problems with falling asleep, staying asleep, or waking too early that affect daytime functioning.
Houston, TexasAges 18–64 - NCT05358067Recruiting
Testing a symptom rating tool after recent trauma
This study looks at how well a clinician’s rating scale (a questionnaire-based score) matches patients’ symptoms after a traumatic event. It may help improve how quickly and accurately symptoms are tracked in the days after trauma.
ArrasAges 18 years+ - NCT05149534Recruiting
Brain stimulation plus writing therapy for PTSD symptoms
This trial tests whether a type of brain stimulation (rTMS) combined with a structured writing therapy can reduce PTSD symptoms in veterans. It may help by boosting how the brain processes traumatic memories while you work through them in writing.
Temple, TexasAges 18–60 - NCT04953273Recruiting
Case management support for adult women after violence
This study tests an organized “case management” plan for adult women who seek medical/forensic help after experiencing serious violence or threats. The goal is to improve how support and next steps are organized after the incident.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for stress disorders, traumatic?
- Yes. Clin2 currently lists 276 recruiting stress disorders, traumatic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stress disorders, traumatic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stress disorders, traumatic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.