Clinical trials
Treatment as Usual clinical trials
Below are recruiting treatment as usual clinical trials, each written for real people, not researchers. We’re tracking 319 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07161661Recruiting
Osteopathic treatment for chronic low back pain in veterans
This trial tests whether adding osteopathic manipulative treatment (OMT) to standard VA care helps reduce chronic low back pain. OMT involves a healthcare provider using their hands to move and stretch muscles and joints.
Hines, IllinoisAges 18 years+ - NCT05489068Recruiting
Motivational interviewing approach for people starting addiction treatment
This study compares two ways of having conversations when you begin outpatient addiction treatment. It tests whether a motivational interviewing style at intake improves your engagement and involvement in your care.
Albuquerque, New MexicoAges 18 years+ - NCT06269510Recruiting
Study to help alcohol-related liver disease patients drink less
This study is testing new ways to help people with alcohol-related liver disease reduce their drinking. Researchers will check if a program offered through your regular liver clinic can help you drink less and stay healthier.
Detroit, MichiganAges 18 years+ - NCT07486401Recruiting
Blood eosinophil-guided asthma care in primary care
This trial tests whether using a blood test (eosinophil count) to guide asthma treatment works better than usual care for people with mild to moderate asthma. If you have asthma and are on step 1-3 treatment, this study could help improve your symptom control.
SingaporeAges 21–65 - NCT07170007Recruiting
Physiotherapy after birth trauma for first-time mothers
This study tests a special physiotherapy program for first-time mothers who had a vaginal tear or episiotomy during childbirth. The goal is to see if it helps recovery better than standard care.
Ribeirão Preto, São PauloAges 18 years+ - NCT07168629Recruiting
Community health workers help you get lung cancer screening
This trial tests whether a community health worker can help you get a lung cancer screening. If you are at risk for lung cancer and go to certain community health centers, this program may help you get the screening you need.
Springfield, MassachusettsAges 50–80 - NCT06029270RecruitingPhase 2
Adding relatlimab to standard immunotherapy for nasopharyngeal cancer
This trial tests whether adding a new drug called relatlimab to the usual immunotherapy (nivolumab) helps people with nasopharyngeal cancer that has returned or spread. You will get standard chemotherapy plus nivolumab first, then if it works, you may be randomly assigned to get nivolumab alone or with relatlimab.
Dublin, CaliforniaAges 18 years+ - NCT06580041Enrolling by invitationPhase 4
Precision treatment for major depression
This trial tests a personalized approach to treating major depressive disorder using assessments and brain imaging to match you with the best therapy. It aims to improve outcomes by tailoring care to your specific needs.
San Francisco, CaliforniaAges 18 years+ - NCT05733767RecruitingPhase 2
Nurse-led help to quit smoking after heart or lung illness
This Phase 2 study tests a nurse practitioner–led program and medicine plan to help you stop smoking after certain heart or lung conditions. It may help you quit and stay smoke-free, while using lab testing (like breath measurements) to confirm progress.
Springfield, MassachusettsAges 18 years+ - NCT06886165Recruiting
New therapy for teens with multiple life problems
This trial tests a new therapy called AMBIT (Adaptive Mentalization-based Integrative Treatment) to help teens facing multiple challenges. It compares the new therapy to the usual care to see if it works and is practical.
Roskilde, Region SjællandAges 12–17 - NCT07014293Recruiting
Building resilience after lymphoma treatment
This study tests a program to help people who recently finished treatment for lymphoma build resilience and cope with the challenges of survivorship. It uses telehealth so you can join from home.
Boston, MassachusettsAges 18 years+ - NCT06047301Recruiting
Pathways: A hope program for advanced lung cancer patients
This study tests a program called 'Pathways' that helps people with advanced lung cancer set personal goals, manage mental health, and improve quality of life. It's for those who are already receiving IV cancer treatment and are feeling some distress.
Lexington, KentuckyAges 18 years+ - NCT06218472Recruiting
Early day hospital treatment for teens with anorexia
This study tests whether starting day hospital treatment early helps teenagers with anorexia nervosa improve their eating habits and supports their families. It is for adolescents who have had anorexia for less than one year and are not severely underweight.
Paris, IDFAges 12 years+ - NCT05613985Recruiting
Ultrasound light added to usual care for infected diabetic foot ulcers
This trial tests whether adding the VULNOFAST Plus/VULNOLIGHT system to usual care can heal infected diabetic foot ulcers more safely and effectively. It compares the added treatment plus usual care versus usual care alone.
ArezzoAges 18 years+ - NCT05627674Enrolling by invitation
Help improve lung cancer screening and quitting support uptake
This study tests a “precision” approach to help people who are newly eligible for lung cancer screening actually get screened and start smoking-cessation treatment. If it works, it could make screening and quitting help easier to access and more engaging.
St Louis, MissouriAges 18 years+ - NCT07101887Recruiting
Comparing two surgeries for thumb arthritis pain and function
This trial tests if a thumb joint replacement works better than the standard surgery for reducing pain and improving hand use in people with thumb arthritis (grades I to III).
BarcelonaAges Any age - NCT06515236Enrolling by invitation
A study of depression treatment for teens from minority groups
This study is testing a new way to help teens (ages 12–18) from racial or ethnic minority groups who are feeling depressed. It looks at how working with a specially trained therapist can improve their mental health.
New Haven, ConnecticutAges 12 years+ - NCT06786832Recruiting
Trial for fatigued patients in primary care
This trial studies severe fatigue that started at a specific time and is not due to another illness. It aims to find better ways to diagnose, treat, and support people with long-term fatigue in primary care.
Stockholm, GustavsbergAges 18–67 - NCT07091734RecruitingPhase 2
Tirzepatide for partial lipodystrophy: a new treatment study
This trial is testing a medication called tirzepatide (Mounjaro) to see if it can help people with a rare fat disorder called familial partial lipodystrophy. The study hopes to improve blood sugar control and lower triglycerides, which are often high in this condition.
Ann Arbor, MichiganAges 18 years+ - NCT06618638Recruiting
Shared Decision Tool for ADPKD Treatment
This study helps people with ADPKD and moderate kidney damage decide together with their doctor whether to start a treatment called tolvaptan. It tests a shared decision-making tool to see if it helps patients understand their options better.
Anyang-si, Gyeonggi-doAges 18–80 - NCT07563244Recruiting
Computer Brain Training for Confusion in Older Adults
This study tests whether using a computer program to do brain exercises can help older adults recover from delirium—a state of confusion that sometimes happens after hospitalization. The goal is to see if this mental stimulation helps people think more clearly and recover faster.
Reus, TarragonaAges 60 years+ - NCT06965010Enrolling by invitation
Tracking Care in Opioid Treatment Programs
This study tests whether tracking your progress with regular check-ins (measurement-based care) helps improve treatment for people starting medication for opioid use disorder at a treatment program.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05053867RecruitingPhase 3
Inhaled drug to treat lung bleeding in ventilated cancer patients
This Phase 3 study tests whether inhaled tranexamic acid can reduce lung bleeding (pulmonary hemorrhage) in people with cancer who are on a breathing machine. If you qualify, you may receive the study drug to help stop bleeding in the lungs.
Houston, TexasAges 18 years+ - NCT06980103Recruiting
Decision aid for RAI in thyroid cancer
This trial offers a decision aid to help you choose whether to have radioactive iodine (RAI) treatment after thyroid cancer surgery. You may qualify if you have intermediate-risk thyroid cancer and haven't yet made a decision about RAI.
Washington D.C., District of ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for treatment as usual?
- Yes. Clin2 currently lists 319 recruiting treatment as usual studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment as usual trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment as usual trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.