Clinical trials
Treatment as Usual clinical trials
Below are recruiting treatment as usual clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05859204Enrolling by invitation
Exercise groups to improve mental health in hospital
This study tests whether joining structured exercise groups while you’re an inpatient in a psychiatric unit can improve mood, mental wellbeing, and overall comfort. It’s designed to be adjustable for different mobility needs and to be safe for participating patients.
Baltimore, MarylandAges 18 years+ - NCT04937309Recruiting
Vagus nerve stimulation for nausea from chemo
This trial tests a non-invasive device that stimulates a nerve in your ear to help prevent nausea caused by chemotherapy. It is for people with breast cancer who are about to start a specific type of chemo (anthracycline and cyclophosphamide).
BloisAges 18 years+ - NCT05031364Recruiting
CBT skills coaching for youth with autism and emotional needs
This study tests a therapy program (called CBT) that helps children with autism who also struggle with emotional or behavioral regulation. It aims to reduce emotional outbursts and improve coping while receiving care through community providers.
Culver City, CaliforniaAges 6–14 - NCT05079464Recruiting
Exercise plus brain stimulation to improve memory in early impairment
This trial tests whether a supervised exercise program, paired with brain stimulation, can improve thinking and memory in people with early “vascular” cognitive problems (not dementia). It may help your brain function before memory loss becomes more severe.
Toronto, OntarioAges 50 years+ - NCT05142683Recruiting
Test an integrated care plan for teens with depression
This study tests whether a structured, coordinated care pathway helps teens (and their caregivers) manage depression better than usual care. It aims to see if targeted treatment and follow-up improve depression symptoms over time.
Toronto, OntarioAges 13–18 - NCT05162794Recruiting
Laparoscopic surgery for endometriosis: does it help or harm?
This study compares whether a minimally invasive surgery to remove endometriosis tissue helps relieve pelvic pain, or causes unwanted effects. You may be asked to rate your pain and follow the study plan around the time of surgery.
Horsens, Central JutlandAges 18–50 - NCT05198830RecruitingPhase 2
Adding TRC102 to standard chemoradiation for stage III lung cancer
This Phase 2 trial tests whether adding TRC102 to standard chemotherapy plus radiation can improve outcomes for people with stage III non-squamous, non-small cell lung cancer. It is designed for newly staged patients and aims to help the immune system work better while treating the tumor.
Buena Park, CaliforniaAges 18 years+ - NCT05208190RecruitingPhase 4
Clozapine to prevent violence in schizophrenia
This trial tests whether clozapine can reduce repeat violent behavior in people with schizophrenia or schizoaffective disorder. Participants are randomly assigned to clozapine or usual care to see which approach works better for preventing violence.
Los Angeles, CaliforniaAges 18–65 - NCT05415007Recruiting
Support program for parents and teens after a new cancer diagnosis
This study tests a brief program meant to reduce anxiety and build resilience in families when a child was newly diagnosed with cancer. It involves both the parent and the child (ages 8–17) and requires consent/assent and English ability.
San Francisco, CaliforniaAges 8–18 - NCT05493254Recruiting
Telehealth help to quit smoking in primary care visits
This study tests a phone/video-based program to help people quit smoking through primary care. It may help you get support and track your progress remotely.
Charleston, South CarolinaAges 18 years+ - NCT05540288RecruitingPhase 3
Nalmefene vs placebo to reduce cravings in behavioral addictions
This study tests whether nalmefene, a non-opioid medicine, can reduce craving episodes in people with behavioral addictions like gambling, food addiction, or sexual addiction. Participants keep tracking cravings weekly, and compare the nalmefene effect against a placebo in addition to their usual care.
BesançonAges 18 years+ - NCT05577585Recruiting
Ketamine treatment for obsessive-compulsive disorder symptoms
This study tests whether ketamine can reduce obsessive-compulsive disorder (OCD) symptoms and how it affects stress and thinking. It also compares ketamine to usual care to see if benefits and side effects differ.
Vienna, State of ViennaAges 18 years+ - NCT05620719Recruiting
Study delayed headache after head injury in veterans
This study looks at treatment for ongoing headache that starts or gets worse after a mild or moderate head/neck injury in veterans or active-duty service members. It may help by testing an approach aimed at reducing headache burden and improving daily functioning.
Los Angeles, CaliforniaAges 18–70 - NCT05624931Recruiting
Helping pregnant women stay on PrEP after starting it
This study tries to reduce the psychological barriers that make it hard for pregnant or postpartum women to keep taking PrEP. It may help by offering support tailored to stress, trauma symptoms, or depression—especially soon after PrEP is started.
Boston, MassachusettsAges 15 years+ - NCT05726721Recruiting
Study of treatment targets for binge eating disorder
This trial studies how binge eating disorder behaves during treatment and compares patterns over time. It may help by improving future treatment approaches for people with binge eating disorder.
Aarhus, Central JutlandAges 18 years+ - NCT05762705Recruiting
Mobile game app to help you take PrEP
This trial tests whether a mobile gaming app can help people stick with PrEP (HIV prevention) so doses aren’t missed. It may help you stay on track during the first month after starting or restarting PrEP.
Boston, MassachusettsAges 15–34 - NCT05793151Recruiting
Guided care to start cancer treatment on time after surgery
This trial tests a navigation program (help from a care coordinator) versus usual care to help people start the recommended “next-step” treatments (like radiation, sometimes with chemo) on time after surgery. It’s for certain stages of squamous cell cancer in the head and neck area where late treatment could matter.
St Louis, MissouriAges 18 years+ - NCT05796401RecruitingPhase 3
Personalized care program for early psychosis outcomes
This trial tests whether a personalized care plan improves day-to-day functioning for people in the early stages of psychosis. It aims to see if adding structured support after a recent diagnosis can help you function better.
BrestAges 15–30 - NCT05803382RecruitingPhase 1
Adding a new drug to capecitabine for metastatic colorectal cancer
This Phase 1 study tests a new anti-cancer drug (ZEN003694) added to the usual chemotherapy capecitabine. It is for adults with colorectal cancer (and possibly other cancers) that has spread or cannot be removed and has continued despite prior standard treatment.
Irvine, CaliforniaAges 18 years+ - NCT05837676Recruiting
Problem-solving training for concussion symptoms
This trial tests whether a structured problem-solving skill program can improve mood and thinking symptoms after a concussion. It may help Veterans who have had concussion symptoms for several months and are currently feeling psychological distress.
Buffalo, New YorkAges 18 years+ - NCT05840198Recruiting
Dog-assisted therapy for youth in residential care
This study tests whether a structured therapy program with a canine (dog) can improve outcomes for youth receiving residential inpatient services. If you qualify, you would be asked to complete baseline tasks and, if assigned, attend at least one of the dog-therapy sessions over about 6 weeks.
Chicago, IllinoisAges 8–18 - NCT05842161Recruiting
Help quitting smoking for people with HIV and TB care
This study supports quitting smoking while you are receiving HIV and/or TB care. It aims to improve engagement in care and smoking cessation for people who smoke daily.
RondeboschAges 18 years+ - NCT05851950Recruiting
Group CBT to reduce rumination in psychosis
This trial tests a structured group therapy (rumination-focused CBT) to help reduce repetitive negative thinking (“rumination”) that can worsen symptoms in people with psychosis. It may help you feel less stuck in unhelpful thoughts and improve day-to-day functioning while you continue your usual care.
CopenhagenAges 18–37 - NCT05861752Recruiting
Study of sexual risk behaviors and mental health patterns
This case-control study looks at people with specific sexual behavior-related conditions (like certain paraphilias, compulsive sexual behavior, or sex during sleep) to understand factors linked with risk for sexual violence. The goal is to learn what patterns may be involved so better help and prevention strategies can be developed.
Stockholm, Stockholm CountyAges 18 years+
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Common questions
- Are there clinical trials for treatment as usual?
- Yes. Clin2 currently lists 315 recruiting treatment as usual studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment as usual trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment as usual trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.