Clinical trials
Treatment as Usual clinical trials
Below are recruiting treatment as usual clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06972368Recruiting
Home brain stimulation for depression in borderline personality disorder
This trial tests whether a gentle brain stimulation device (tDCS) used at home can help with depression in people with borderline personality disorder. If you have BPD and current depression, you may be able to participate from home using your smartphone.
Montreal, QuebecAges 18–65 - NCT05577585Recruiting
Ketamine treatment for obsessive-compulsive disorder symptoms
This study tests whether ketamine can reduce obsessive-compulsive disorder (OCD) symptoms and how it affects stress and thinking. It also compares ketamine to usual care to see if benefits and side effects differ.
Vienna, State of ViennaAges 18 years+ - NCT06880796Enrolling by invitation
Mindfulness therapy for serious mental illness
This trial tests whether mindfulness-based therapy helps people with serious mental illnesses like schizophrenia or mood disorders. You'll learn mindfulness skills in a group setting at your community mental health center.
Providence, Rhode IslandAges 18 years+ - NCT06884943RecruitingPhase 2
AI tool to help kids generalize speech skills
This study tests if an AI-powered system can help children ages 9 to 17 generalize the speech sounds they learned in a previous study. It's for kids who already completed the VISIT trial and showed some progress.
Bloomfield, New JerseyAges 9–17 - NCT06869057Recruiting
Improving diabetes care after hospital discharge
This study tests a redesigned discharge process to help people with type 2 diabetes manage their health after leaving the hospital. It focuses on patients who also have unmet social needs, like food or housing issues.
Worcester, MassachusettsAges 18 years+ - NCT06859060Recruiting
Improving health for people with serious mental illness
This study helps people with serious mental illness like schizophrenia or bipolar disorder who also have chronic health conditions (e.g., diabetes, overweight) get better overall care. It focuses on improving health and wellness through preventive medical care in Puerto Rico.
Mayagüez, Puerto RicoAges 21 years+ - NCT06863909Enrolling by invitation
Journaling plus cognitive behavioral therapy for better results
This trial explores whether adding journaling to your regular cognitive behavioral therapy sessions helps you feel better more quickly. You keep seeing your therapist as usual, just add a few minutes of writing each day.
TübingenAges 18–65 - NCT06864715Recruiting
Preventing depression after a stroke with behavioral activation
This study tests if a talking therapy called behavioral activation can prevent depression in older adults who have had a stroke and have low income. It is for people who are not already severely depressed and live at home.
Houston, TexasAges 55 years+ - NCT06853925Recruiting
Online program for thyroid cancer symptom management
This study tests a web-based program to help people with thyroid cancer manage symptoms from radioactive iodine (RAI) treatment and improve their quality of life. It is for those who have had RAI within the past three years and are experiencing mild to moderate symptoms.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06837311Recruiting
Smoking cessation after stroke via smartphone monitoring
This study tests a smartphone-based program that helps people who recently had a stroke quit smoking. It uses digital monitoring and support as part of your regular post-stroke follow-up to lower the risk of another stroke.
BordeauxAges 18–80 - NCT06831942Recruiting
Suicide prevention counseling for adults 65 and older
This study tests a short counseling program for older adults (65+) who have recently attempted suicide or had serious suicidal thoughts. The program is designed to help reduce the risk of future suicide attempts. It is offered alongside your regular mental health care.
BoråsAges 65 years+ - NCT06832605Recruiting
Mindfulness classes by video to prevent depression relapse
This trial tests an 8-week mindfulness-based cognitive therapy program delivered via video call to help people with a history of depression prevent future episodes. It may help you learn skills to manage low mood and reduce the chance of relapse.
Elche, AlicanteAges 18 years+ - NCT06829953Recruiting
App-based study for teens with depression
This study is testing whether a smartphone app can help teens who feel depressed and have lost interest in things. It's looking for youth aged 12–18 with moderate to severe depression who are willing to use the app.
Philadelphia, PennsylvaniaAges 12–18 - NCT06811116RecruitingPhase 1/Phase 2
Sapanisertib plus cabozantinib for advanced liver cancer
This trial studies a combination of two drugs for advanced liver cancer with a specific gene change. The goal is to see if adding sapanisertib to the usual cabozantinib treatment helps people live longer without their cancer growing.
Irvine, CaliforniaAges 18 years+ - NCT06779838Enrolling by invitation
Group EFT for eating difficulties in student counselling
This trial tests if group Emotional Freedom Techniques (a type of talking therapy that combines focusing on emotions with tapping on certain body points) can help students with eating concerns. You might join if you have mild to moderate eating or body image issues and are already linked with your school's counselling service.
Royal Tunbridge Wells, KentAges 18 years+ - NCT06770582RecruitingPhase 2
Adding immunotherapy to radiation for bladder cancer
This trial tests whether adding the immunotherapy drug pembrolizumab to radiation therapy works as well as or better than the usual chemotherapy given with radiation for a type of bladder cancer that has not invaded the muscle. It is for people whose cancer came back or has high-risk features and who would otherwise need to have their bladder removed.
Tucson, ArizonaAges 18 years+ - NCT04244721Recruiting
Parent training program for children with autism
This trial tests whether a parent-led program (with PACT) can improve autism-related symptoms in children. It focuses on giving parents structured support, and it compares outcomes after families complete the program.
BronAges 1.5 years–3 years - NCT06290167Recruiting
Dual-task rehab for memory concerns in older adults
This study tests a new rehab program that combines physical and mental tasks for older adults with early memory issues. It aims to help improve daily function and possibly slow decline.
Milan, MIAges 65 years+ - NCT06722027Recruiting
Spiritual health program for healthcare teams
This study looks at whether a program focused on spiritual health can help healthcare teams feel less stressed and more connected. It is for employees working in cancer care or intensive care at Emory.
Atlanta, GeorgiaAges 18 years+ - NCT05935722Recruiting
Home parenting support for parents of young children
This study tests a home-based parenting support program designed for parents who have learning or attention differences (like autism or ADHD). It aims to give tailored strategies to help you manage parenting daily challenges for children aged 0 to 9.
EnköpingAges Any age - NCT06675461Enrolling by invitation
Brief talk therapy for suicidal patients with borderline personality disorder
This trial tests a short talk therapy for people with borderline personality disorder who come to the emergency department after hurting themselves or thinking about suicide. The goal is to see if this brief help can ease suicidal thoughts and keep you safer.
Toronto, OntarioAges 16 years+ - NCT06678672Recruiting
Help for veterans who smoke before major surgery
This study tests a program to help veterans who smoke quit before a planned major surgery. The program uses rewards to encourage quitting, and it may improve surgery outcomes.
San Francisco, CaliforniaAges 18 years+ - NCT05840198Recruiting
Dog-assisted therapy for youth in residential care
This study tests whether a structured therapy program with a canine (dog) can improve outcomes for youth receiving residential inpatient services. If you qualify, you would be asked to complete baseline tasks and, if assigned, attend at least one of the dog-therapy sessions over about 6 weeks.
Chicago, IllinoisAges 8–18 - NCT06654037RecruitingPhase 1
Testing abemaciclib plus 5-FU for advanced colorectal cancer
This trial is testing whether adding a targeted drug called abemaciclib to the standard chemotherapy 5-FU can help people with a specific type of advanced colorectal cancer (MSS) that has stopped responding to other treatments. The goal is to see if this combination is safe and effective.
Irvine, CaliforniaAges 18 years+
Hear when a new Treatment as Usual trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for treatment as usual?
- Yes. Clin2 currently lists 315 recruiting treatment as usual studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment as usual trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment as usual trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.