Clinical trials
Treatment as Usual clinical trials
Below are recruiting treatment as usual clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06651528Enrolling by invitation
Trauma support program for substance use and reentry
This study tests a program for people in correctional facilities who have experienced violence and are in substance use treatment. It helps you prepare for release by building a support system in the community.
Frankfort, KentuckyAges 18–99 - NCT06639477Recruiting
Mood and sleep improvement study for older adults
This study tests whether adding a sleep treatment to regular depression medication can improve both mood and sleep in adults aged 55 and older. It may help if you have ongoing depression, sleep problems, and are already taking antidepressant medication.
Los Angeles, CaliforniaAges 55 years+ - NCT06611878Recruiting
Music training for Alzheimer's patients at home
This trial tests whether intensive music training can help memory in people with Alzheimer's disease who live at home and are not musicians.
Buenos AiresAges 65 years+ - NCT06614868Recruiting
Stress counseling for LGBTQ+ individuals
This study tests a counseling program designed to help LGBTQ+ people cope with stress related to their identity. It may help you if you're looking for support dealing with the unique challenges of being a sexual minority.
Birmingham, AlabamaAges 18 years+ - NCT06593379Recruiting
Mobile app for suicidal thoughts
This study tests a mobile app designed to help veterans manage suicidal thoughts. Participation may provide extra support between mental health visits.
Durham, North CarolinaAges 18 years+ - NCT06592677Recruiting
Early support after trauma
This trial tests if early support from a municipal crisis team can help people who have been through a traumatic event. It may be a good option if you have symptoms of post-traumatic stress and want to see if extra support soon after the event can help you feel better.
Asker, AskerAges 16–99 - NCT06573476Recruiting
Smartphone app and peer coach for opioid treatment
This study tests whether a smartphone app and support from a peer recovery coach can help Black and Latinx individuals with opioid use disorder start buprenorphine treatment. The goal is to reduce overdose deaths and address racial gaps in care.
New York, New YorkAges 18–99 - NCT06531980Recruiting
Digital app for teens with mild to moderate anxiety
This trial tests a digital app to help teens with mild to moderate anxiety. If you are 13–16, live in Bergen, and feel anxious often, this app might help you manage your worries and get back to doing things you enjoy.
Bergen, VestlandAges 13–16 - NCT06526247Recruiting
Testing programs for intimate partner violence in Washington state
This study tests support programs for men who have been court-referred for intimate partner violence in Washington state. It also includes their partners to see how well the programs work.
Boston, MassachusettsAges 18 years+ - NCT05837676Recruiting
Problem-solving training for concussion symptoms
This trial tests whether a structured problem-solving skill program can improve mood and thinking symptoms after a concussion. It may help Veterans who have had concussion symptoms for several months and are currently feeling psychological distress.
Buffalo, New YorkAges 18 years+ - NCT06498648RecruitingPhase 1/Phase 2
Abemaciclib with gemcitabine for soft tissue sarcoma
This trial tests whether adding the targeted drug abemaciclib to standard chemotherapy (gemcitabine) works better against certain soft tissue sarcomas. It is for people whose tumors have a normal Rb gene, which may help the drug work.
Houston, TexasAges 18 years+ - NCT06499740Recruiting
Supporting teens with suicidal thoughts in primary care
This study tests a short, supportive conversation for teens with suicidal thoughts that happens in their regular doctor's office. It aims to help teens and their families get the right care without needing a hospital stay.
Centralia, WashingtonAges 10 years+ - NCT06013748Recruiting
Virtual reality therapy for voice hearing
This trial tests if virtual reality therapy can help people who hear distressing voices. It compares VR therapy to a waitlist to see if it gives you more control over the voices.
Groningen, Provincie GroningenAges 16 years+ - NCT06460220Enrolling by invitation
Online support for parents of suicidal teens
This study tests an online course for parents of teenagers who have had suicidal thoughts, to help them better support their child. It is for families already getting care at a specific clinic at Nationwide Children's Hospital.
Columbus, OhioAges 10–18 - NCT06466356Recruiting
Learning to prevent suicide after a crisis
This trial tests a short educational program to help people who have had a suicide attempt or serious suicidal thoughts. The goal is to reduce future risk by teaching coping skills and support strategies.
Levanger, TrøndelagAges 18–99 - NCT06442514Recruiting
Pain and Smoking Study: Phone Support for Veterans
This study tests a phone-based program to help Veterans with chronic pain quit smoking. If you're a VA patient who uses tobacco and has ongoing pain, you may be able to join and get support from home.
West Haven, ConnecticutAges 18 years+ - NCT06454136Enrolling by invitation
App-based support for teens after a suicide attempt
This trial tests a mobile app designed to help teenagers who have recently been hospitalized after a suicide attempt or serious suicidal thoughts. The goal is to see if the app can provide extra support and reduce future suicide attempts.
Hartford, ConnecticutAges 13–17 - NCT06432985Recruiting
Smoking cessation coaching for veterans with cancer
This study tests a counseling program to help veterans who smoke quit smoking, especially those undergoing cancer treatment or lung cancer screening. It may improve health outcomes during cancer care.
San Francisco, CaliforniaAges 18 years+ - NCT06434571RecruitingPhase 2
Comparing two sleep treatments for people with MS
This trial tests if talking with a sleep coach by video is better than a web-based program for improving sleep, reducing fatigue, and protecting the brain in people with multiple sclerosis (MS). Both treatments focus on changing thoughts and habits around sleep.
Kansas City, KansasAges 18–65 - NCT06430333RecruitingPhase 2
Sleep therapy to prevent depression in pregnancy
This study tests whether a sleep-focused therapy can help prevent depression in pregnant people who have insomnia. If you are 14–31 weeks pregnant and have trouble sleeping, this trial offers a program to improve your sleep and lower your risk of depression.
Novi, MichiganAges 18 years+ - NCT06353711Recruiting
Caring Connections youth suicide detection and support
This study looks at better ways to find and help youth who are thinking about suicide or hurting themselves, especially those who have had trouble getting mental health services. It uses a team approach to connect youth with care and support.
Charlotte, North CarolinaAges 13 years+ - NCT06345872Recruiting
Better sleep to help reduce opioid use for chronic pain
This study tests a sleep improvement program to help people with chronic widespread pain reduce or stop their opioid pain medication. If you want to cut back on opioids and have trouble sleeping, this treatment might be a good fit.
Tampa, FloridaAges 18 years+ - NCT06317662RecruitingPhase 2
Adding venetoclax and blinatumomab to chemo for infant leukemia
This trial tests adding two newer medicines (venetoclax and blinatumomab) to standard chemotherapy for infants with a specific type of leukemia. The goal is to see if this combination helps more babies stay cancer-free.
Birmingham, AlabamaAges Up to 12 months - NCT06309329Enrolling by invitation
Strength at Home for Veteran Parents: A Study
This study tests a program called Strength at Home for veteran parents. It helps improve parenting and reduce stress for veterans with PTSD who have a child between 3 and 12 years old.
Temple, TexasAges 18 years+
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Common questions
- Are there clinical trials for treatment as usual?
- Yes. Clin2 currently lists 315 recruiting treatment as usual studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment as usual trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment as usual trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.