Clinical trials
Tuberculosis Infection clinical trials
Below are recruiting tuberculosis infection clinical trials, each written for real people, not researchers. We’re tracking 34 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05610098Recruiting
Study of gene activity in spinal tuberculosis
This trial looks at patterns of gene activity (from blood/tissue samples) in adults with spinal tuberculosis. The goal is to better understand the disease and how to tell different conditions apart, which may help future care.
Cape Town, Western CapeAges 18 years+ - NCT05756582Recruiting
Screening for hidden TB infection in hospital staff and students
This trial checks hospital workers and certain medical students to see how many have “latent TB,” meaning TB bacteria in the body that may not cause symptoms. The goal is to better understand who might need follow-up and prevention.
RomaAges 18–72 - NCT06033807Recruiting
Screening for hidden TB in school contacts
This study tests a program to find hidden (latent) tuberculosis infections in students who have been close to someone with active TB. It helps identify who might need treatment to prevent them from getting sick later.
Zunyi, GuiyangAges 13 years+ - NCT06221488Recruiting
TB testing for health workers at risk
This study tests health workers for tuberculosis (TB) infection to better understand who is at risk. It may help find ways to protect health workers from TB.
Cape TownAges 18–100 - NCT07086820Recruiting
Window prophylaxis for preventing TB in children
This trial tests if a short course of medication can prevent tuberculosis (TB) in children and teenagers who have been in close contact with someone who has active TB. The goal is to see if this approach can stop them from developing the disease.
Calama, AntofagastaAges 5–17 - NCT06728930Enrolling by invitation
New test for diagnosing latent and active TB
This study tests a new type of lab test to find TB bacteria more accurately. It is for people who are being checked for latent (hidden) TB infection, or who have just been diagnosed with active TB. The goal is to see if the new test can help doctors diagnose TB better and faster.
LondonAges 18 years+ - NCT06352970Recruiting
TB infection and placenta function study
This study looks at how tuberculosis (TB) infection might affect the placenta and its function during pregnancy. If you are pregnant and giving birth soon, researchers want to learn if TB changes how the placenta grows and works.
Addis AbabaAges 18 years+ - NCT01212003Recruiting
Study of how tuberculosis develops over time
This study follows people with suspected or confirmed tuberculosis (TB), whether they have inactive “latent” TB or active TB. It helps researchers better understand TB’s natural course and may improve future testing and care by allowing collection and storage of samples.
Bethesda, MarylandAges 2–100 - NCT04271397Recruiting
Testing immune blood markers in tuberculosis care
This study looks at immune system blood tests in adults being treated for active tuberculosis and/or latent tuberculosis infection. The goal is to see if these “immune biomarkers” can help guide or improve tuberculosis management.
LyonAges 18 years+ - NCT06764576Recruiting
Study for people with suspected tuberculosis or related infections
This trial is looking for adults who might have tuberculosis, a related infection called non-tubercular mycobacteriosis, or a hidden (latent) tuberculosis infection. You will provide a sample for testing, and the study will help doctors understand and manage these infections better.
BolognaAges 18 years+ - NCT05069688RecruitingPhase 1
Testing dolutegravir dosing in HIV and TB children
This study looks at the right way to dose dolutegravir (an HIV medicine) in young children who also have active tuberculosis (TB). Doctors will measure how the medicine moves through the body, especially when standard vs higher-dose rifampicin is used.
Ibadan, Oyo StateAges 4 weeks–5 years - NCT05022862Recruiting
Check how incentives and vDOT help latent TB treatment
This trial studies whether reminder-based “vDOT” and small economic incentives can help people complete treatment for latent (sleeping) tuberculosis. If you have latent TB and are starting a standard medicine plan, it may help you stay on track and finish safely.
Baltimore, MarylandAges 18 years+ - NCT05443178RecruitingPhase 1
Testing chloroquine added to tuberculosis treatment for safety
This Phase 1 study tests how safe and tolerable chloroquine is when given alongside standard tuberculosis medicine. It mainly involves healthy volunteers and helps researchers understand side effects and safe dosing.
ZurichAges 18–50 - NCT06289660Recruiting
Italian study on tuberculosis in children
This study follows children and teens with different stages of tuberculosis (TB) across Italy. It aims to learn more about how TB affects young people and improve care.
Florence, FirenzeAges 1 week–18 years - NCT04052022Recruiting
Study of TB flare-ups in people without HIV
This study looks at why some people with tuberculosis (TB) get worse or develop new inflammation after they initially start improving on treatment—called a “paradoxical reaction.” It collects blood and tissue samples to better understand these flare-ups and guide future care.
Bethesda, MarylandAges 18–99 - NCT07152639RecruitingPhase 3
New skin test for tuberculosis in people 3 and older
This trial tests a new skin test (EEC) to see if it can accurately detect tuberculosis infection in people aged 3 and older. It compares the test's results in healthy people, people with TB, and people with other lung diseases to check how well it works.
Beijing, Beijing MunicipalityAges 3 years+ - NCT05655702Recruiting
Drug use and infections study for tuberculosis control in Vietnam
This study looks at how injecting drug use is linked with infections, including tuberculosis, and aims to improve TB control. You may be asked to share information and provide tests related to recent drug use and injection sites.
HaiphongAges 18 years+ - NCT05590455RecruitingPhase 2
Testing a TNF-blocking drug to reduce death in HIV and TB meningitis
This Phase 2 trial studies whether a TNF-blocking medicine can lower the risk of death in people with HIV who also have TB meningitis. You would receive standard TB meningitis treatment plus the study drug, if you meet the criteria.
Rio de JaneiroAges 18 years+ - NCT05588492RecruitingPhase 4
Rifamycin treatment to prevent TB after kidney transplant
This study looks at whether a rifamycin-containing medicine plan is safe and effective at preventing latent (hidden) TB after a kidney transplant. If your TB test shows you likely have hidden TB, you would be offered treatment to reduce the chance it becomes active TB.
TaipeiAges 20 years+ - NCT05842161Recruiting
Help quitting smoking for people with HIV and TB care
This study supports quitting smoking while you are receiving HIV and/or TB care. It aims to improve engagement in care and smoking cessation for people who smoke daily.
RondeboschAges 18 years+ - NCT05947890RecruitingPhase 2
Testing an immune-boosting TB vaccine in people with or without HIV
This Phase 2 study tests MTBVAC, a TB vaccine candidate, to see if it is safe and whether it helps the immune system. It may be a fit if you’re eligible for TB and HIV-related vaccine safety testing and can follow study visits and testing.
Johannesburg, GautengAges 12–55 - NCT06338215Recruiting
Moderate drinking vs. abstention advice for adults
This study compares two approaches for adults who drink regularly: advice on drinking in moderation vs. advice to stop drinking entirely. The goal is to see which approach better prevents major diseases and early death over time.
Pamplona, NavarreAges 50–75 - NCT06498414RecruitingPhase 2/Phase 3
Shorter and safer treatment for latent TB
This trial tests a shorter, safer treatment for people with latent TB infection (TB germs in your body but not making you sick). The goal is to prevent you from getting sick with active TB later.
CotonouAges 5 years+ - NCT07164742Recruiting
Recovery help for lung health after TB treatment
This study tests whether a lung rehabilitation program (like physical therapy for your lungs) can help people who recently started TB treatment breathe and feel better. You need a smartphone and must be willing to attend sessions for 48 weeks.
MangaloreAges 18 years+
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Common questions
- Are there clinical trials for tuberculosis infection?
- Yes. Clin2 currently lists 34 recruiting tuberculosis infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tuberculosis infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tuberculosis infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.