Clinical trials
Type 2 Diabetes (T2DM) clinical trials
Below are recruiting type 2 diabetes (t2dm) clinical trials, each written for real people, not researchers. We’re tracking 229 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06863532Recruiting
Comparing two add-on treatments for type 2 diabetes
This trial compares adding a new pill (cofrogliptin) to increasing your current metformin dose, for people whose blood sugar is still too high despite taking an SGLT2 inhibitor and a low dose of metformin. The goal is to see which option works better and is safer.
Hangzhou, ZhejiangAges 18–74 - NCT07329231Recruiting
Quinoa for early type 2 diabetes control
This study tests whether adding quinoa to your diet can help manage blood sugar and improve how your body uses insulin. It focuses on people recently diagnosed with type 2 diabetes.
Jinan, ShandongAges 20–70 - NCT07317115Recruiting
Comparing a new surgery to a diabetes drug for weight loss
This trial compares a new surgical procedure (duodeno-ileostomy) to a medication (semaglutide) for people with obesity and type 2 diabetes. It aims to see which approach works better for weight loss and blood sugar control.
Westmount, QuebecAges 18 years+ - NCT07314684RecruitingPhase 4
Semaglutide's effect on inflammation in type 2 diabetes
This study tests whether the diabetes medication semaglutide can reduce inflammation and improve blood vessel health in people with type 2 diabetes who have no significant heart artery blockages. If you have diabetes and are at moderate to high heart risk but haven't had heart problems, this could help understand the medicine's extra benefits beyond blood sugar control.
Caserta, CasertaAges 18–85 - NCT07309094Recruiting
Effects of a diabetes drug on fat tissue in kidney disease
This trial tests whether a GLP-1 receptor agonist (a type of diabetes medication) can improve fat tissue health in people with chronic kidney disease who also have type 2 diabetes, cardiovascular disease, or obesity. It may help protect your kidneys and overall health.
Valencia, ValenciaAges 18–90 - NCT07303803RecruitingPhase 2
Testing Chiglitazar for fatty liver with diabetes
This trial tests a new oral medication, Chiglitazar, for people who have both type 2 diabetes and a fatty liver condition called MASH (fatty liver with inflammation and scarring). It aims to see if the drug can help improve liver health and diabetes control.
Beijing, Beijing MunicipalityAges 18–75 - NCT07286500Recruiting
Sex, diabetes, and low blood sugar risk
This study looks at how sexual activity affects blood sugar levels and the risk of low blood sugar (hypoglycemia) in adults with diabetes who use insulin and a continuous glucose monitor. By participating, you'll help researchers understand the safety of sexual activity for people with diabetes.
WarsawAges 18 years+ - NCT07285330Recruiting
Dietitian or Day Hospital for Type 2 Diabetes Control
This trial compares two ways to help people with type 2 diabetes improve their blood sugar control: working with a dietitian-nutritionist or attending a day hospital program. It's for people who are on insulin but not getting enough results from current care.
Vilafranca del Penedès, BarcelonaAges 18 years+ - NCT07270731RecruitingPhase 1
Study of a new medicine for type 2 diabetes and healthy volunteers
This study tests a new medicine (NNC9733-0001) to see how it works in healthy people and in people with type 2 diabetes. It helps researchers understand safety and how the body processes the drug.
NeussAges 18–64 - NCT07275788RecruitingPhase 1
Study of REGEND003 for type 2 diabetes with kidney disease
This trial tests a new treatment, REGEND003, for people who have both type 2 diabetes and chronic kidney disease. The goal is to see if it can help manage these conditions together.
ShanghaiAges 30–75 - NCT07272343RecruitingPhase 4
Semaglutide vs. diet changes for new type 2 diabetes
This study compares a weekly injection called semaglutide with a calorie-restricted diet to see which helps control blood sugar better. If you have just been diagnosed with type 2 diabetes and have overweight, this trial might help you choose a treatment path.
Jiangxi, NanchangAges 18–75 - NCT07252765Recruiting
Nutritional Drink for Diabetes with Malnutrition Risk
This study is testing whether a special diabetes drink (high in calories, protein, and fiber) helps people with type 2 diabetes who are at risk of malnutrition. If you have diabetes and have been prescribed this drink, you may be able to join.
Santander, CantabriaAges 18 years+ - NCT07250789Recruiting
Brain Care Study: Screen and help for thinking decline in type 2 diabetes
This study screens older adults with type 2 diabetes for early signs of memory or thinking problems, and offers a program to help keep the brain healthy. It aims to find out if a combination of lifestyle changes, mental exercises, and medical support can slow cognitive decline.
CopenhagenAges 65 years+ - NCT07244003RecruitingPhase 4
Testing metformin with two newer diabetes drugs
This trial is testing if adding a combination of SGLT-2 inhibitor and GLP-1 receptor agonist to metformin can improve blood sugar control in people with type 2 diabetes who are not meeting their goals on metformin alone or with one other pill.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07241221Recruiting
Myo-inositol supplement for diabetes in pregnancy
This study tests whether taking a supplement called myo-inositol (a natural vitamin-like substance) during pregnancy can help manage blood sugar in women with type 2 diabetes. It may improve outcomes for you and your baby.
Singapore, SingaporeAges 21–45 - NCT07241325Recruiting
Emotional health and quality of life in type 2 diabetes
This study looks at how adults with type 2 diabetes feel emotionally and mentally, and how their health affects their daily life. Participants will fill out questionnaires about their mood, well-being, and quality of life.
TaipeiAges 18 years+ - NCT07246421Recruiting
Glucagon resistance in fatty liver and diabetes
This study looks at how people with fatty liver and type 2 diabetes respond to glucagon, a hormone that helps control blood sugar. It may help researchers understand a condition called 'glucagon resistance' and find better treatments.
AarhusAges 30–70 - NCT04501406RecruitingPhase 2
Low-dose pioglitazone for fatty liver disease in people with type 2 diabetes
This Phase 2 study tests whether low-dose pioglitazone can improve NASH, a type of fatty liver disease, in adults who also have type 2 diabetes. You may be able to join if your diabetes medicines and lab tests meet specific safety and stability requirements.
Gainesville, FloridaAges 21–75 - NCT06912321Recruiting
Brain Circuit Study for Type 2 Diabetes
This study uses MRI scans to look at a specific brain circuit (the Papez loop) in people with type 2 diabetes. It aims to understand how diabetes might affect brain networks related to memory and emotion.
Nanjing, JiangsuAges 45–70 - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT07197775Enrolling by invitation
Endogenex PULSE Registry: Tracking long-term outcomes
This registry collects information from people with type 2 diabetes who have already been treated with the Endogenex System. It helps researchers learn how the treatment works over time.
Quincy, MassachusettsAges 18 years+ - NCT07193459RecruitingPhase 3
Study of an oral tablet for type 2 diabetes
This trial tests an experimental daily tablet for adults with type 2 diabetes who are not currently on any diabetes medication. It aims to see if the tablet can safely lower blood sugar levels over time.
Beijing, Beijing MunicipalityAges 18–75 - NCT07195045Recruiting
Thai PainPREDICT validation study for diabetes nerve pain
This study tests a tool (PainPREDICT) to predict nerve pain in people with diabetes. It aims to identify those at risk so treatment can start early.
Pathum Wan, BangkokAges 18 years+ - NCT07187479Recruiting
Testing a new insulin approach for kidney disease and diabetes
This study tests a new approach to help your body use insulin better, which may improve blood sugar control and slow down kidney disease. It is for people with advanced chronic kidney disease and type 2 diabetes who are not yet on dialysis.
Phoenix, ArizonaAges 18 years+
Hear when a new Type 2 Diabetes (T2DM) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for type 2 diabetes (t2dm)?
- Yes. Clin2 currently lists 229 recruiting type 2 diabetes (t2dm) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 2 diabetes (t2dm) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 2 diabetes (t2dm) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.